Effect of L-NAME, an inhibitor of nitric oxide synthesis, on cardiopulmonary function in human septic shock [PDF]
, 1998 STUDY OBJECTIVES: We tested the effects of continuous infusion of N(G)-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide (NO) synthesis, on cardiovascular performance and pulmonary gas exchange in patients
Avontuur, J.A.M. +4 more
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The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice [PDF]
, 2016 There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator.
Bukoski RD +6 more
core +2 more sources
Nitric oxide synthase inhibition attenuates cardiac response to hemodilution with viscogenic plasma expander. [PDF]
, 2014 Background and objectivesIncreased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution.
Cabrales, Pedro, Chatpun, Surapong
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Nitric oxide modulation of glutamatergic, baroreflex, and cardiopulmonary transmission in the nucleus of the solitary tract [PDF]
, 2005 The neuromodulatory effect of NO on glutamatergic transmission has been studied in several brain areas. Our previous single-cell studies suggested that NO facilitates glutamatergic transmission in the nucleus of the solitary tract (NTS).
Colombari, Eduardo +3 more
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Исследования и практика в медицине, 2018 Aim. To study the effect of non-selective inhibitor of NO-synthase N-nitro-L-arginine methyl ester (L-NAME) and substrate of nitric oxide synthesis L-arginine on the activity of cathepsins B, L, H and its subcellular distribution in liver, kidney and lung
M. A. Fomina, A. A. Terent'ev
doaj +1 more source
EXPERIMENTAL PARTICIPATION OF PHARMACOLOGICAL SUBSTANCES IN MECHANISMS OF LEAD ACETATE TOXICITY
Фармация и фармакология (Пятигорск), 2023 The aim of the work is to study pharmacological substances that play a role of eNOS expression regulators in the modification of lead intoxication effects in the experiment.Materials and methods.
S. G. Dzugkoev +4 more
doaj +1 more source
A newly discovered interference of the central nitrergic system on oxytocin-induced hypophagia in layer-type chickens [PDF]
The Iranian Journal of Veterinary Science and Technology, 2021 Various neurochemical pathways are participating in the regulation of food intake in mammals and birds. Both oxytocin (OT) and nitric oxide (NO) are known as hypophagic agents in birds.
Morteza Zendehdel +5 more
doaj +1 more source
Effect of injection of L-NAME on drinking response [PDF]
Brazilian Journal of Medical and Biological Research, 1999 The drinking behavior responses to centrally administered N G-nitro-L-arginine methyl ester (L-NAME; 10, 20 or 40 microg/microl), an inhibitor of nitric oxide synthase, were studied in satiated rats, with cannulae stereotaxically implanted into the lateral ventricle (LV) and subfornical organ (SFO).
Saad, W.A. +4 more
openaire +7 more sources
Biology Open, 2021 The contractions of Chelonoidis carbonaria aortic rings induced by electrical field stimulation (EFS) are not inhibited by blockade of the voltage-gated sodium channels by tetrodotoxin but almost abolished by the α1/α2-adrenoceptor antagonist ...
José Britto-Júnior +10 more
doaj +1 more source
Effects of NO synthase inhibitors on the synovial microcirculation in the mouse knee joint [PDF]
, 1999 Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses.
Krombach, F. +3 more
core +1 more source