Results 21 to 30 of about 713,418 (262)

Participation of kinins in the inhibitory action of captopril on acute hypertension induced by L-NAME in anesthetized rats

Brazilian Journal of Medical and Biological Research, 1997
The aim of the present study was to investigate the role of bradykinin in the inhibitory action of captopril in hypertension induced by L-NAME in anesthetized rats.
R. Soares de Moura, M. Cardoso
doaj   +1 more source

Açaí (Euterpe oleracea Mart) seed extract protects against maternal vascular dysfunction, hypertension, and fetal growth restriction in experimental preeclampsia

Hypertension in Pregnancy, 2020
Objective To investigate whether Euterpe oleracea Mart. (açaí) seed extract (ASE) prevents maternal cardiovascular changes and intrauterine growth restriction (IUGR) in experimental preeclampsia (PE).
Alexandre de Souza da Silva, Douglas Val Quintans Nunes, Lenize Costa dos Reis Marins de Carvalho, Izabelle Barcellos Santos, Matheus Pontes de Menezes, Graziele Freitas de Bem, Cristiane Aguiar da Costa, Roberto Soares de Moura, Angela Castro Resende, Dayane Teixeira Ognibene   +9 more
doaj   +1 more source

Sympathetic activation in rats with L-NAME-induced hypertension [PDF]

Brazilian Journal of Medical and Biological Research, 2007
We evaluated the hemodynamic pattern and the contribution of the sympathetic nervous system in conscious and anesthetized (1.4 g/kg urethane, iv) Wistar rats with L-NAME-induced hypertension (20 mg/kg daily). The basal hemodynamic profile was similar for hypertensive animals, conscious (N = 12) or anesthetized (N = 12) treated with L-NAME for 2 or 7 ...
Biancardi, V.C., Bergamaschi, C.T., Lopes, O.U., Campos, R.R.   +3 more
openaire   +5 more sources

The analgesic effects of L-arginine and its antagonist LNAM

The Iraqi Journal of Veterinary Medicine, 2012
L-arginine-Nitric oxide pathway plays an important role in a series of neurobiological functions underlying behaviors including analgesic effect and has shown a role in pain feeling which is a mediator with modulation effect in dorsal root of ...
Farid J. Al-Tahan, Muhannad A. A. Al-Bayati, Salma J. Askar   +2 more
doaj   +3 more sources

Сhanges in subcellular distribution of lysosomal cysteine proteinases activity in parenchymatous organs of rats under the action of nitric oxide synthesis modulators

Исследования и практика в медицине, 2018
Aim. To study the effect of non-selective inhibitor of NO-synthase N-nitro-L-arginine methyl ester (L-NAME) and substrate of nitric oxide synthesis L-arginine on the activity of cathepsins B, L, H and its subcellular distribution in liver, kidney and lung
M. A. Fomina, A. A. Terent'ev
doaj   +1 more source

EXPERIMENTAL PARTICIPATION OF PHARMACOLOGICAL SUBSTANCES IN MECHANISMS OF LEAD ACETATE TOXICITY

Фармация и фармакология (Пятигорск), 2023
The aim of the work is to study pharmacological substances that play a role of eNOS expression regulators in the modification of lead intoxication effects in the experiment.Materials and methods.
S. G. Dzugkoev, F. S. Dzugkoeva, O. I. Margieva, A. E. Khubulova, I. V. Mozhaeva   +4 more
doaj   +1 more source

A newly discovered interference of the central nitrergic system on oxytocin-induced hypophagia in layer-type chickens [PDF]

The Iranian Journal of Veterinary Science and Technology, 2021
Various neurochemical pathways are participating in the regulation of food intake in mammals and birds. Both oxytocin (OT) and nitric oxide (NO) are known as hypophagic agents in birds.
Morteza Zendehdel, Mina Khodadadi, Homeyra Zandiyeh, Kasra Mokhtarpouriani, Behrouz Rahmani, Ali Baghbanzadeh   +5 more
doaj   +1 more source

The basal release of endothelium-derived catecholamines regulates the contractions of Chelonoidis carbonaria aorta caused by electrical-field stimulation

Biology Open, 2021
The contractions of Chelonoidis carbonaria aortic rings induced by electrical field stimulation (EFS) are not inhibited by blockade of the voltage-gated sodium channels by tetrodotoxin but almost abolished by the α1/α2-adrenoceptor antagonist ...
José Britto-Júnior, Felipe Fernandes Jacintho, Rafael Campos, David Halen Araújo Pinheiro, Guilherme M. Figueiredo Murari, Valéria B. de Souza, André A. Schenka, Fabíola Z. Mónica, Ronilson Agnaldo Moreno, Edson Antunes, Gilberto De Nucci   +10 more
doaj   +1 more source

The L-NAME effects in acute experimental peritonitis

Science and Innovations, 2022
The article presents the results of research to study the course of experimental peritonitis in rats under administration of non-selective NO-synthase inhibitor, Nώ-nitro-L-arginine methyl ester (L-NAME). It has been shown that administration of L-NAME results in increase in the severity of in-toxication, reaction of leukocytes of blood and peritoneal ...
E. Gusakovskaya, N. Maksimovich
openaire   +1 more source

Hesperidin, a citrus flavonoid, protects against l-methionine-induced hyperhomocysteinemia by abrogation of oxidative stress, endothelial dysfunction and neurotoxicity in Wistar rats

Pharmaceutical Biology, 2017
Context: Hesperidin (HSP), a flavanoglycone found in citrus fruits, has antioxidant, anti-inflammatory and neuroprotective properties. Objective: This study evaluates the protective effect of HSP on l-methionine-induced hyperhomocysteinemia (HHcy) in ...
B. Hemanth Kumar, B. Dinesh Kumar, Prakash V. Diwan   +2 more
doaj   +1 more source