Effect of L-NAME, an inhibitor of nitric oxide synthesis, on cardiopulmonary function in human septic shock [PDF]
, 1998 STUDY OBJECTIVES: We tested the effects of continuous infusion of N(G)-nitro-L-arginine methyl ester (L-NAME), an inhibitor of nitric oxide (NO) synthesis, on cardiovascular performance and pulmonary gas exchange in patients
Avontuur, J.A.M. +4 more
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Nitric oxide synthase inhibition attenuates cardiac response to hemodilution with viscogenic plasma expander. [PDF]
, 2014 Background and objectivesIncreased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution.
Cabrales, Pedro, Chatpun, Surapong
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The analgesic effects of L-arginine and its antagonist LNAM
The Iraqi Journal of Veterinary Medicine, 2012 L-arginine-Nitric oxide pathway plays an important role in a series of neurobiological functions underlying behaviors including analgesic effect and has shown a role in pain feeling which is a mediator with modulation effect in dorsal root of ...
Farid J. Al-Tahan +2 more
doaj +3 more sources
A newly discovered interference of the central nitrergic system on oxytocin-induced hypophagia in layer-type chickens [PDF]
The Iranian Journal of Veterinary Science and Technology, 2021 Various neurochemical pathways are participating in the regulation of food intake in mammals and birds. Both oxytocin (OT) and nitric oxide (NO) are known as hypophagic agents in birds.
Morteza Zendehdel +5 more
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Исследования и практика в медицине, 2018 Aim. To study the effect of non-selective inhibitor of NO-synthase N-nitro-L-arginine methyl ester (L-NAME) and substrate of nitric oxide synthesis L-arginine on the activity of cathepsins B, L, H and its subcellular distribution in liver, kidney and lung
M. A. Fomina, A. A. Terent'ev
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EXPERIMENTAL PARTICIPATION OF PHARMACOLOGICAL SUBSTANCES IN MECHANISMS OF LEAD ACETATE TOXICITY
Фармация и фармакология (Пятигорск), 2023 The aim of the work is to study pharmacological substances that play a role of eNOS expression regulators in the modification of lead intoxication effects in the experiment.Materials and methods.
S. G. Dzugkoev +4 more
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The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice [PDF]
, 2016 There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator.
Bukoski RD +6 more
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Effect of injection of L-NAME on drinking response [PDF]
Brazilian Journal of Medical and Biological Research, 1999 The drinking behavior responses to centrally administered N G-nitro-L-arginine methyl ester (L-NAME; 10, 20 or 40 microg/microl), an inhibitor of nitric oxide synthase, were studied in satiated rats, with cannulae stereotaxically implanted into the lateral ventricle (LV) and subfornical organ (SFO).
Saad, W.A. +4 more
openaire +7 more sources
Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone [PDF]
, 2014 Background: Nearly 50% of patients with heart failure (HF) have preserved LV ejection fraction, with interstitial fibrosis and cardiomyocyte hypertrophy as early manifestations of pressure overload.
Coelho‐Filho, Otavio R. +6 more
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Toxic effects of methoxychlor on the episodic prolactin secretory pattern: Possible mediated effects of nitric oxide production [PDF]
, 2006 Background This work addresses the issue of whether methoxychlor (MTX) exposure may modify the ultradian secretion of prolactin through changes in the synthesis of nitric oxide (NO) induced by Nω-nitro-L-arginine methyl ester (L-NAME) in the hypothalamic-
Anunciación Lafuente +3 more
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