Results 71 to 80 of about 714,437 (290)

Curcumin reduces inflammation process in mice model preeclampsia

Majalah Obstetri dan Ginekologi
HIGHLIGHTS • Increased oxidative stress results in increased iNOS in pre-eclampsia. • COX-2 expression in the placenta of women suffering from preeclampsia increases and is associated with increased thromboxane production.   ABSTRACT Objective:
Bambang Rahardjo, Agung Widyalaksono, Irfani Baihaqi   +2 more
doaj   +1 more source

Renoprotective Effects of Melatonin in Young Spontaneously Hypertensive Rats with L-NAME

Pediatrics and Neonatology, 2014
Nitric oxide (NO) deficiency occurs in humans and animals with hypertension and chronic kidney disease (CKD). An inhibitor of NO synthase, NG-nitro-l-arginine methyl ester (L-NAME) exacerbates kidney damage in the adult spontaneously hypertensive rat ...
Ming-Chou Cheng, Ting-Hsin Wu, Li-Tung Huang, You-Lin Tain   +3 more
doaj   +1 more source

Gebe ve gebe olmayan wistar albino sıçanlarda l-name, L-name+ dekzametazon ve L-name+ dekzametazon kombinasyonunun perifer kan basıncına etkileri

, 2021
The study investigated the effects of the L-NAME and dexamethasone (DEXA) on blood pressure of rats from a Wistar albino rat colony seemingly resistant to L-NAME hypertension. For this, two simultaneous experiments using a total of 62 pregnant and non-pregnant Wistar albino rats were carried out.
openaire   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Intrastriatal pre-treatment with L-NAME protects rats from diquat neurotoxcity. [PDF]

Annals of agricultural and environmental medicine : AAEM, 2012
Contact herbicide diquat (DQ), redox cycling compound, mediates its systemic toxicity throughout the enlarged production of free radicals. Target organs are liver and kidney in humans. To-date, the mechanism of DQ-induced neurotoxicity has not been rationalized.The objectives of the study were to examine the ability of DQ to induce oxidative stress (OS)
Đukić, Mirjana, Jovanović, Marina, Ninković, Milica, Stevanović, Ivana, Ćurčić, Marijana, Topić, Aleksandra, Vujanović, Dragana, Đurđević, Dragan   +7 more
openaire   +2 more sources

Изучение эффектов сочетанного применения эналаприла и лозартана с милдронатом при L-NAME-индуцированной эндотелиальной дисфункции [PDF]

, 2011
Результаты изучения эндотелио- и кардиопротективных эффектов милдроната, эналаприла, лозартана и их комбинации при L-NAME-индуцированной эндотелиальной дисфункции у самцов белых крысyesКурский государственный медицинский ...
Дронова, Т. А., Корокин, М. В., Покровская, Т. Г., Покровский, М. В., Юдина, Н. В.   +4 more
core   +1 more source

Pharmacological efficacy of an inhibitor of arginase-2 KUD975 with L-NAME-induced endothelial dysfunction [PDF]

, 2017
The study of endotelio- and cardioprotective activity of finished dosage forms - tablets, film-coated, containing 10 mg of phenolic nature KUD-975, was shown a statistically significant decrease in blood pressure and the coefficient of endothelial ...
Gudyrev, O. S., Korokin, M. V., Kudryavtsev, K. V.   +2 more
core   +2 more sources

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source

CORRECTION OF EXPERIMENTAL L-NAME-INDUCED PRE-ECLAMPSY BY INHIBITOR OF ARGINASE L-NORVALINE AND ITS COMBINATIONS WITH PREPARATIONS OF STANDARD TREATMENT SCHEME

Кубанский научный медицинский вестник, 2014
Experimental L-NAME-induced pre-eclampsia model in rats was achieved by L-NAME administration from 14 to 20 pregnancy days. Blood pressure elevation, gestational proteinuria, placenta microcirculation impairing, vascular tone dysregulation, and L ...
O. S. Poljanskaja, M. V. Pokrovsky
doaj  

Potential effects of L-NAME on alcohol-induced oxidative stress

World Journal of Gastroenterology, 2005
Nitric oxide (NO) is a highly reactive oxidant synthesized from L-arginine by nitric oxide synthase (NOS). NO may cause injury through the generation of potent radicals. Nw- nitro-L-arginine methyl ester (L-NAME) is a non-selective inhibitor of NOS. We aimed to evaluate whether L-NAME treatment had protective effects against oxidative stress in rats ...
Hafize, Uzun, Gonul, Simsek, Seval, Aydin, Ethem, Unal, Yesari, Karter, Nermin-Karaturan, Yelmen, Suphi, Vehid, Asl, Curgunlu, Safiye, Kaya   +8 more
openaire   +2 more sources