Results 51 to 60 of about 729,292 (310)

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Ambulatory Cardiovascular Activities in L-NAME-Treated Mice [PDF]

The Open Hypertension Journal, 2011
Objective: High blood pressure (BP) is a dominant risk factor in cardiovascular diseases. An experimental model of nitric oxide synthase (NOS) inhibitor induced hypertension was developed to study some etiologic mechanisms in cardiovascular parameters. Methods: Cardiovascular rhythm characteristics were documented in mice following the N-omega-nitro-L ...
openaire   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Индуцирование синтеза NO в корнях проростков пшеницы и развития их теплоустойчивости экзогенными L-аргинином и нитратом [PDF]

, 2017
Показано, что обработка корней интактных проростков пшеницы (Triticum aestivum L.) L-аргинином и нитратом натрия вызывает увеличение в них содержания оксида азота (NO) и повышает устойчивость к повреждающему прогреву.
Дмитриев, А.П., Карпец, Ю.В., Колупаев, Ю.Е.   +2 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Nitric oxide synthase mediates the antioxidant effect of L-Arginine in the brain of mice subjected to chronic restrain stress

SVU-International Journal of Veterinary Sciences, 2022
Chronic restraint stress (CRS) immobilize animal and induces the production of oxidative radicals as a preliminary cause of various health complications.
Abdellah Hassan, Zeinab Al-Amgad, Mohammed Youssef   +2 more
doaj   +1 more source

The effect of hydroalcoholic extract of Achillea eriophora DC. on blood pressure of anaesthetized male rat [PDF]

, 2016
Achillea eriophora (Asteraceae) is a medicinal plant commonly used in Iran. This study was performed to determine the cardiovascular effects of hydroethanolic extract of A. eriophora (HEAE) and the underlying mechanisms in anaesthetized rats.
Anvari, Sohrab, Bahaoddini, Aminollah, Khosravi, Ahmad Reza, Moein, Mahmoodreza   +3 more
core   +1 more source

The role of nitric oxide synthase isoforms in aged porcine oocytes

Czech Journal of Animal Science, 2013
In the sphere of reproductive biotechnologies, the demand for sufficient numbers of high-quality oocytes is still increasing. In some cases, this obstacle is overcome by in vitro prolonged cultivation.
J. Nevoral, T. Krejčová, J. Petr, P. Melicharová, A. Vyskočilová, M. Dvořáková, I. Weingartová, E. Chmelíková, L. Tůmová, K. Hošková, V. Kučerová-Chrpová, M. Sedmíková   +11 more
doaj   +1 more source

Cardioprotective Effect of Whole Body Periodic Acceleration in Dystrophic Phenotype mdx Rodent

Frontiers in Physiology, 2021
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle wasting and the development of a dilated cardiomyopathy (DCM), which is the leading cause of death in DMD patients.
Arkady Uryash, Alfredo Mijares, Eric Esteve, Jose A. Adams, Jose R. Lopez, Jose R. Lopez   +5 more
doaj   +1 more source

An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]

, 2012
Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Agmon Y, Armulik A, Bogle RG, Bratosin D, C. Crawford, C. Sprott, C.M. Peppiatt-Wildman, Crawford C, Cupples WA, Dahlstrom A, Dietrich HH, Dunn KW, Hall AM, Hamilton NB, Holliger C, Horiuchi T, Hughes S, J. Munday, Jans D, Kawamura H, L. Sawbridge, Landis EM, MacPhee PJ, Mattson DL, Mattson DL, O’Connor PM, Pallone TL, Pallone TL, Pallone TL, Pallone TL, Pallone TL, Park F, Patzak A, Peppiatt CM, Praetorius HA, R.J. Unwin, Rhinehart K, Rhinehart KL, Roman RJ, S.S.P. Wildman, Shepro D, Silldorff EP, Silldorff EP, Silldorff EP, Sprague RS, T. Desai, T. Kennedy-Lydon, Thiel G, Whitehouse T, Wu DM, Zhang Z, Zhang Z   +51 more
core   +2 more sources