Results 11 to 20 of about 139,625 (161)

Nanoscale regulation of L-type calcium channels differentiates between ischemic and dilated cardiomyopathies. [PDF]

EBioMedicine, 2020
Sanchez-Alonso JL, Loucks A, Schobesberger S, van Cromvoirt AM, Poulet C, Chowdhury RA, Trayanova N, Gorelik J.   +7 more
europepmc   +2 more sources

Calenduloside E suppresses calcium overload by promoting the interaction between L-type calcium channels and Bcl2-associated athanogene 3 to alleviate myocardial ischemia/reperfusion injury. [PDF]

J Adv Res, 2021
Wang R, Wang M, Zhou J, Dai Z, Sun G, Sun X.   +5 more
europepmc   +2 more sources

Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channels to Vasorelaxant Mechanisms

Frontiers in Pharmacology, 2021
Background: The current study presents the novel angiotensin II receptor blocker fluorophenyl benzimidazole (FPD) as an antihypertensive agent in the SHR model of hypertension.
Hina Iqbal, Amit Kumar Verma, Pankaj Yadav, Sarfaraz Alam, Mohammad Shafiq, Divya Mishra, Feroz Khan, Kashif Hanif, Arvind Singh Negi, Debabrata Chanda   +9 more
doaj   +1 more source

Hydrogen sulfide regulates the colonic motility by inhibiting both L-type calcium channels and BKCa channels in smooth muscle cells of rat colon. [PDF]

PLoS ONE, 2015
To examine the hypothesis that hydrogen sulfide (H2S) regulates the colonic motility by modulating both L-type voltage-dependent calcium channels and large conductance Ca2+-activated K+ (BKCa) channels.Immunohistochemistry was performed on rat colonic ...
Xiaojing Quan, Hesheng Luo, Yin Liu, Hong Xia, Wei Chen, Qincai Tang   +5 more
doaj   +1 more source

Autoregulation of Cardiac l-Type Calcium Channels [PDF]

Trends in Cardiovascular Medicine, 2009
l-Type calcium channels (LTCCs) are major contributors to electrical and contractile function of the heart. They regulate action potential duration, enable calcium entry into cardiac myocytes for contraction, and regulate growth-related signaling in the heart.
Jonathan, Satin, Elizabeth A, Schroder
openaire   +2 more sources

Leukotriene B4 Inhibits L-Type Calcium Channels via p38 Signaling Pathway in Vascular Smooth Muscle Cells

Cellular Physiology and Biochemistry, 2015
Background/Aims: Arachidonic acid (AA) and its metabolites are important endogenous lipid messengers. In this study, we test the effect of Leukotriene B4 (LTB4), a 5-lipoxygenase metabolite of AA, on L-type calcium channels in A7r5 rat aortic vascular ...
Xiaoyu Liu, Tingting Yang, Langxi Miao, Yan-Ai Mei, Changlong Hu   +4 more
doaj   +1 more source

Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells. [PDF]

PLoS ONE, 2013
INTRODUCTION:WE REPORTED THAT RYANODINE RECEPTORS ARE EXPRESSED IN TWO DIFFERENT TYPES OF MAMMALIAN PERIPHERAL TASTE RECEPTOR CELLS: Type II and Type III cells. Type II cells lack voltage-gated calcium channels (VGCCs) and chemical synapses.
Michelle R Rebello, Amanda B Maliphol, Kathryn F Medler   +2 more
doaj   +1 more source

T-type calcium channel: a privileged gate for calcium entry and control of adrenal steroidogenesis

Frontiers in Endocrinology, 2016
Intracellular calcium plays a crucial role in modulating a variety of functions such as muscle contraction, hormone secretion, gene expression or cell growth. Calcium signaling has been however shown to be more complex than initially thought.
Michel Florian Rossier, Michel Florian Rossier   +1 more
doaj   +1 more source

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil

Pharmaceutical Biology, 2022
Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański, Magdalena Winkiel, Monika Szymczak-Cendlak, Paweł Marciniak, Dominika Mańczak, Karolina Walkowiak-Nowicka, Marta Spochacz, Sabino A. Bufo, Laura Scrano, Zbigniew Adamski   +9 more
doaj   +1 more source

L-Type Calcium Channels [PDF]

Circulation Research, 2002
Voltage-gated calcium channels are essential for coupling membrane depolarization to the influx of calcium in all excitable cells. The calcium that flows into excitable cells through voltage-gated calcium channels serves a dual function, generating both electrical and chemical signals. The intracellular events controlled by calcium are diverse and many.
openaire   +1 more source