Results 171 to 180 of about 13,174,260 (209)

Evaluation of Macroalgae Sulfated Polysaccharides on the Leishmania (L.) amazonensis Promastigote [PDF]

open access: yesMarine Drugs, 2013
The sulfated polysaccharides from Solieria filiformis (Sf), Botryocladia occidentalis (Bo), Caulerpa racemosa (Cr) and Gracilaria caudata (Gc) were extracted and extensively purified. These compounds were then subjected to in vitro assays to evaluate the inhibition of these polysaccharides on the growth of Leishmania (L.) amazonensis promastigotes ...
Marcos Hikari Toyama   +2 more
exaly   +6 more sources

Evaluation of Experimental Infection with L. (L.) Amazonensis in X-Linked Immunodeficient Mice

Journal of Parasitology, 2017
B-1 cells are a subtype of B cells with peculiar characteristics. These cells are distinct from B-2 lymphocytes in their morphology, ontogeny, tissue distribution, and phenotypic functional features. B-1 cells can participate in the immune response in several ways, for example, by being recruited to inflammatory foci, producing large amounts of IL-10 ...
Gonzaga, Wagner Francisco Kennerly Marcondes UNIFESP   +6 more
openaire   +3 more sources

In vitro efficacy of isoflavonoids and terpenes against Leishmania (Leishmania) infantum and L. amazonensis

Experimental Parasitology, 2022
The main form of control of leishmaniasis is the treatment, however various side effects and poor efficacy are associated with presently available drugs. The investigation of bioactive natural products for new antileishmanial drugs is a valid approach.
Iasmin Aparecida Cunha, Araújo   +8 more
openaire   +2 more sources

Lipidomic alterations of in vitro macrophage infection by L. infantum and L. amazonensis

Molecular BioSystems, 2017
Abstract Particular lipid profiles have been found in two different protozoa of the Leishmania genus. Leishmania infantum, a visceral leishmaniasis causative agent and Leishmania amazonensis, a cutaneous leishmaniasis, reveal distinctive lipid contents of phosphatidylethanolamine and phosphatidylserine plasmalogens, sphingolipids ...
Fernanda Negrão   +7 more
openaire   +2 more sources

Inhibition of mouse lymphocyte proliferative response by glycosphingolipids from Leishmania (L.) amazonensis

Experimental Parasitology, 1992
The effect of a purified preparation of glycosphingolipids (GSLs) extracted from Leishmania (L.) amazonensis amastigotes on murine lymphocytes was investigated. GSLs inhibited both concanavalin A (Con A)- or lipopolysaccharide-induced [3H]thymidine uptake by normal and immunized BALB/c mouse lymph node cells. The effect of total GSLs was dose dependent.
S, Giorgio   +4 more
openaire   +2 more sources

Infection of retinal epithelial cells with L. amazonensis impacts in extracellular matrix proteins

Parasitology Research, 2011
One of the manifestations of leishmaniases is eye injuries which main characteristics are the injury of the anterior chamber of the eye and the resistance to specific treatments. The retinal pigment epithelial (RPE) cells participate in pathogen-induced intraocular inflammatory processes.
Calabrese, Katia da Silva   +6 more
openaire   +3 more sources

Altered transport properties of pentamidine-resistant Leishmania donovani and L. amazonensis promastigotes

Parasitology Research, 1997
Pentamidine-resistant clones of Leishmania donovani and L. amazonensis promastigotes were developed by increase of the drug pressure in the culture medium and characterized. The resistant clones could grow in 40 and 20 microM pentamidine as determined for L. donovani and L.
M, Basselin, F, Lawrence, M, Robert-Gero
openaire   +2 more sources

ExperimentalLeishmania (L.) amazonensisLeishmaniasis: Characterization and Immunogenicity of Subcellular Fractions

Immunological Investigations, 2007
A technique developed in Trypanosoma cruzi biochemical studies was successfully used to fractionate Leishmania (Leishmania) amazonensis promastigotes. Ultrastructural analyses revealed a membrane fraction (MF) associated to subpellicular microtubules, a ribosomal-rich microsomal fraction (MicF), and a flagellar fraction (FF) free of associated membrane.
T Zaverucha, do Valle   +9 more
openaire   +2 more sources

Co-infection by Leishmania amazonensis and L. infantum/L. chagasi in a case of diffuse cutaneous leishmaniasis in Bolivia.

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002
We present the first report of a co-infection by Leishmania amazonensis and L. infantum/L. chagasi isolated in 1993 from a patient with diffuse cutaneous leishmaniasis (DCL), living in the sub-Andean region of Bolivia. This is the third reported case of DCL in Bolivia, but the first one with isoenzymatic identification of the aetiological agents ...
A L Bañuls, M Torrez, F le Pont
exaly   +3 more sources

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