Results 61 to 70 of about 27,247 (266)

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source

Psycholinguistic determinants of reading comprehension in english as a foreign language

Psicologia Escolar e Educacional
The purpose of this study was to analyze the contribution of linguistic and psychological variables in the explanation of the variance associated with reading comprehension in English (L2).
Javier Vivaldo-Lima, Miguel López-Olivas, Rosa Obdulia González-Robles   +2 more
doaj   +1 more source

COMMENTARY: CAN FREE READING TAKE YOU ALL THE WAY? A RESPONSE TO COBB (2007) [PDF]

Language Learning and Technology, 2008
Cobb (2007) argues that free reading cannot provide L2 readers with sufficient opportunities for acquiring vocabulary in order to reach an adequate level of reading comprehension of English texts.
Jeff McQuillan, Stephen D. Krashen
doaj  

A cross-linguistic evaluation of script-specific effects on fMRI lateralization in late second language readers

Frontiers in Human Neuroscience, 2014
Behavioral and neuroimaging studies have provided evidence that reading is strongly left lateralized, and this pattern of functional lateralization can be indicative of reading competence.
Maki Sophia Koyama, Maki Sophia Koyama, John Frederick Stein, Catherine J Stoodley, Peter C Hansen   +4 more
doaj   +1 more source

CHCHD10 Mitigates Alzheimer's Disease‐Related Phenotypes in Association With Epigenetic Remodeling in Directly Reprogrammed Neurons

Advanced Science, EarlyView.
CHCHD10 loss in Alzheimer's disease is associated with mitochondrial dysfunction, epigenomic disruption, and tau pathology. Restoration of CHCHD10 shifts DNA methylation toward a non‐disease state and reduces tau and amyloid pathology, with KATNAL2 acting as a downstream effector.
Teresa M. Thomas, Ching‐Yao Yang, Kexin Zhang, Liam Wetzel, Dina Bugybayeva, Julia Ferguson, Md Mahmudul Hasan, William Samsa, Nandita Patil, Anshul Dash, Tarini Gowda, Xiongwei Zhu, Feixiong Cheng, Tian Liu   +13 more
wiley   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

An Appraisal Look into Iraqi EFL Students' L2 Motivational Self-System and It's Correlation with Their Reading Ability

Journal of Literature and Education
The aim of this study was to examine the relationship between the Iraqi EFL L2 motivating self-system, reading ability, and gender. In order to find answers to the research questions, a correlational methodology was used, and the study was designed as a ...
Ahmed Abed Ali Kadhim, Methaq Kadhim Kaddam   +1 more
doaj   +1 more source

Effects of Task Complexity on L2 Reading and L2 Learning

English Teaching, 2016
Task-based language teaching (TBLT) has propelled much research into how task type, condition, or demand affects L2 learners’ linguistic performance...
openaire   +1 more source

Radiation Resilient Synthetic Antiferromagnets‐Based Neuromorphic Device for Sea Surface Temperature Reconstruction

Advanced Science, EarlyView.
By leveraging strong antiferromagnetic coupling, radiation‐tolerant synthetic antiferromagnetic synaptic devices are developed. Their intrinsic nonlinearity emulates neuronal activation, while linear and symmetric conductance modulation mimics synaptic plasticity.
Mingxu Song, Jiahao Liu, Ruisheng Hu, Teng Xu, Aihua Tang, Zhihong Zhu   +5 more
wiley   +1 more source