Results 51 to 60 of about 128,431 (240)
Development of a Positive-readout Mouse Model of siRNA Pharmacodynamics
Molecular Therapy: Nucleic Acids, 2013 Development of RNAi-based therapeutics has the potential to revolutionize treatment options for a range of human diseases. However, as with gene therapy, a major barrier to progress is the lack of methods to achieve and measure efficient delivery for ...
Mark Stevenson +9 more
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CourseSource, 2019 The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and appreciate ...
A. Crowther +5 more
semanticscholar +1 more source
MicrobiologyOpen, 2019 Bacteria can utilize diverse sugars as carbon and energy source, but the regulatory mechanisms directing the choice of the preferred substrate are often poorly understood.
Tamara Aleksandrzak‐Piekarczyk +2 more
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A modified consumer inkjet for spatiotemporal control of gene expression.
PLoS ONE, 2009 This paper presents a low-cost inkjet dosing system capable of continuous, two-dimensional spatiotemporal regulation of gene expression via delivery of diffusible regulators to a custom-mounted gel culture of E. coli. A consumer-grade, inkjet printer was
Daniel J Cohen +2 more
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Biomedical and Biotechnology Research Journal, 2022 Background: The repeating elements in the genes or genomes of living organisms are associated with a variety of functions at the molecular level. Mirror repeats (MRs) are unique type of repeat sequences among them, which are found to be linked with H-DNA
Sandeep Yadav +2 more
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Stochastic dynamics of macromolecular-assembly networks [PDF]
, 2006 The formation and regulation of macromolecular complexes provides the backbone of most cellular processes, including gene regulation and signal transduction.
Arkin A +4 more
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Regulation of bistability in the std fimbrial operon of Salmonella enterica by DNA adenine methylation and transcription factors HdfR, StdE and StdF [PDF]
, 2019 Bistable expression of the Salmonella enterica std operon is controlled by an AND logic gate involving three transcriptional activators: the LysR-type factor HdfR and the StdE and StdF regulators encoded by the std operon itself.
Casadesús Pursals, Josep +4 more
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Use of a Role-Playing Activity To Increase Student Understanding of Bacterial Gene Regulation
Journal of Microbiology & Biology Education, 2023 Undergraduate students often struggle to understand the basics of bacterial gene regulation, a key concept in microbiology. They find it hard to visualize the architecture of a bacterial operon or how the gene, RNA, and protein components interact with ...
Vinaya Sampath
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A Type System for a Stochastic CLS [PDF]
, 2009 The Stochastic Calculus of Looping Sequences is suitable to describe the evolution of microbiological systems, taking into account the speed of the described activities.
Angelo Troina +3 more
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The Role of Integration Host Factor in Escherichia coli Persister Formation
mBio, 2022 Persisters represent a small subpopulation of cells that are tolerant of killing by antibiotics and are implicated in the recalcitrance of chronic infections to antibiotic therapy.
Samantha E. Nicolau, Kim Lewis
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