Results 71 to 80 of about 113,489 (230)
Stochastic dynamics of macromolecular-assembly networks [PDF]
Nature/EMBO Molecular Systems Biology 2, art. no. msb4100061, pp.
2006.0024 (2006), 2006 The formation and regulation of macromolecular complexes provides the backbone of most cellular processes, including gene regulation and signal transduction. The inherent complexity of assembling macromolecular structures makes current computational methods strongly limited for understanding how the physical interactions between cellular components ...
arxiv +1 more source
Dual mechanism of repression at a distance in the lac operon. [PDF]
Proceedings of the National Academy of Sciences, 1988 The mechanism by which the internal lacZ gene sequence O2 influences lac repression was investigated by using in vivo footprinting of operon mutants. Quantitative in vivo binding curves show that O2 strengthens by approximately 3-fold repressor binding to O1 that is located 400 base pairs upstream at the transcription start site.
Yehuda Flashner, Jay D. Gralla
openaire +3 more sources
Engineered Living Energy Materials
Interdisciplinary Materials, EarlyView.Engineered living energy materials (ELEMs) are nascent research frontier for enabling sustainable energy conversion and storage. These materials exhibit unique characteristics such as self‐regeneration, biodegradability, environmental response, and evolutionary adaptability. This paper overviews different energy conversion bio‐modules, summarizes their
Xinyi Yuan +14 more
wiley +1 more source
Dynamic model of gene regulation for the lac operon
Journal of Physics: Conference Series, 2011 Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria.
Angelova, Maia
openaire +2 more sources
Mass Spectrometry Reviews, EarlyView.Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu +10 more
wiley +1 more source
LacSwitch® II Regulation of Connexin43 cDNA Expression Enables Gap-Junction Single-Channel Analysis
BioTechniques, 2003 Metabolic and electrical coupling through gap junction channels is implicated in cell differentiation, tissue homeostasis, and electrotonic propagation of signals in excitable tissues.
G. Zhong +6 more
doaj +1 more source
Accurate prediction of gene expression by integration of DNA sequence statistics with detailed modeling of transcription regulation [PDF]
Biophys. J. 99, 2408-2413 (2010), 2010 Gene regulation involves a hierarchy of events that extend from specific protein-DNA interactions to the combinatorial assembly of nucleoprotein complexes. The effects of DNA sequence on these processes have typically been studied based either on its quantitative connection with single-domain binding free energies or on empirical rules that combine ...
arxiv +1 more source
Light‐Activated Gene Expression System Using a Caging‐Group‐Free Photoactivatable Dye
Angewandte Chemie, Volume 137, Issue 4, January 21, 2025.A light‐induced gene expression system was developed using a caging‐group‐free photoactivatable dye with a multidrug‐binding transcriptional regulator, QacR. This system allowed transcriptional activation with mild visible light exposure, large dynamic range, and simultaneous detection of the state of the effector molecule in cell‐free and cellular ...
Tatsuki Nonomura +2 more
wiley +2 more sources
Frontiers in Microbiology, 2019 Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan +5 more
doaj +1 more source
Construction of a RFP-lacZα bicistronic reporter system and its application in lead biosensing.
PLoS ONE, 2020 The combination of a fluorescent reporter and enzymatic reporter provides a flexible and versatile way for the study of diverse biological processes, such as the detection of transcription and translation.
Chang-Ye Hui +5 more
doaj +1 more source