Results 141 to 150 of about 50,722 (240)

Synthesis of bicyclic lactams using novel Schmidt reactions

open access: yesARKIVOC, 2003
Mike Casey   +3 more
doaj   +1 more source

Chiral Potassium Brønsted Base‐Catalyzed Stereoselective Synthesis of 1,3‐Diols via a Tandem Allylic Isomerization/Asymmetric Aldol–Tishchenko Reaction

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.
Chiral potassium base catalysts featuring 1,1´‐bi‐2‐naphthol‐derived chiral crown ethers as ligands promote a tandem allylic isomerization/asymmetric aldol‐Tishchenko reaction of allylic alcohols and aldehydes. This method provides enantioenriched 1,3‐diols with excellent diastereoselectivity and high enantioselectivity, thereby expanding the synthetic
Hiroki Ishikawa, Masahiro Sai
wiley   +1 more source

Triplet Energy Transfer‐Driven Intermolecular [2+2] Photocycloaddition of Acyclic Imines and Indoles: Facile Access to Azetidine‐Fused Indolines

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang   +3 more
wiley   +1 more source

Penicillin allergy de‐labelling in the critical care unit: Simulations to design an intravenous drug provocation test that mirrors the plasma profile of an enteral challenge

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 997-1002, March 2026.
The majority of penicillin allergy labels are incorrect and a label of penicillin allergy is associated with worse outcomes and increased use of healthcare services. Penicillin allergy assessment and de‐labelling may be considered in critically ill patients. An oral penicillin challenge is a common component of most penicillin allergy protocols.
Cleodie Swire   +7 more
wiley   +1 more source

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