Results 11 to 20 of about 74,505 (292)
Visible-Light-Mediated Lewis Acid-Catalyzed Diradical Hydrogen Atom Transfer Reaction of Enamides. [PDF]
The Lewis acid catalysis was crucial for the success of the DHAT reaction of enamides by lowering the energy of the triplet excited state and modulating the reactivity of the formed diradical intermediate in a carbon‐to‐carbon 1,5‐DHAT and consequent cyclization that allows the functionalization of C(sp3)−H bonds to construct a variety of novel β ...
Huang Y +5 more
europepmc +2 more sources
Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Hadfield, Peter S. +4 more
core +5 more sources
Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines [PDF]
This work is supported by a Royal Society for a University Research Fellowship and the EPSRC and GSK (Case Award) as well as by the European Research Council under the European Unionʼs Seventh Framework Programme (FP7/2007-2013) (ERC Grant Agreement No ...
Prevet, Hugues +5 more
core +1 more source
The Versatile Reactivity of Oximes with Vinyl Boronic Acids and Development of 4-Phosphono-β-Lactams [PDF]
The tunable reactivity of oximes with alkenyl boronic acids towards C–O versus C–N bond formation has been explored. O-alkenyl oximes have been evaluated as precursors to α-imino aldehydes by a copper-mediated etherification of benzophenone oxime with ...
Dimitra Kontokosta (1909459)
core +6 more sources
.GAMMA.-Lactam analogues of .BETA.-lactam antibiotics.
In vitro interactions between aztreonam (AZT) and 8 other antibiotics were studied using the agar dilution checkerboard technique against 88 clinical isolates of Escherichia coli, Proteus vulgaris, Serratia marcescens and Pseudomonas aeruginosa. Combinations of AZT with 8 other antibiotics were generally additive or indifferent.
J E, Baldwin, G P, Lynch, J, Pitlik
openaire +3 more sources
A calorimetric study of β-sultams and β-lactams [PDF]
The hydrolytic degradation of a series of β-sultams and β-lactams was investigated using isothermal microcalorimetry (IMC), to determine kinetic and enthalpic data.
Naz, Summia
core +3 more sources
Fast Solvent-free Alkylation of Amides and Lactams under Microwave Irradiation
N-Substituted amides and lactams are rapidly N-alkylated under solvent-free phase-transfer catalytic conditions using microwaves.
Dariusz Bogdal
doaj +1 more source
Fungal Lactamases: Their Occurrence and Function
Fungi are absorptive feeders and thus must colonize and ramify through their substrate to survive. In so doing they are in competition, particularly in the soil, with myriad microbes.
Minglu Gao +3 more
doaj +1 more source
Steroidal lactams are also a class of steroid derivatives that were synthesized and modified to increase the biological activity of steroids. Their synthesis is a stimulating challenge to the scientist, often claiming the development of new and generally useful reactions.
Ibrahim-Ouali, Malika, Dumur, Frédéric
openaire +2 more sources
Direct Access to Substituted 4-CF3 β-Lactams at the C-3 Position
Mono- and disubstituted 4-CF3 β-lactams at the C-3 position have been obtained stereoselectively under basic conditions. A wide range of function such as alcohols, alkyls, aryls, esters, and double and triple bonds have been introduced.
Monika Skibińska +8 more
doaj +1 more source

