Results 21 to 30 of about 52,808 (261)
Frontiers in CatalysisThe CoA ligase from Metallosphaera sedula (MsACL) can be used for the chemoenzymatic synthesis of amides from carboxylic acids. In this CoA-independent conversion, the enzyme catalyzes the adenylation of a carboxylic acid with the help of ATP, followed ...
Nikolas Capra +7 more
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The synthesis of (±)-(1R,6R,7R)-2-azabicyclo[4.2.0]octan-7-ol
Журнал органічної та фармацевтичної хіміїAn approach to the synthesis of (±)-(1R,6R,7R)-2-azabicyclo[4.2.0]octan-7-ol, a promising amino alcohol building block for drug discovery, has been described. The method is based on [2+2] the cycloaddition of tert-butyl vinyl ether and a ketene generated
Danylo A. Nosyk +4 more
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Beilstein Journal of Organic Chemistry, 2018 The synthesis of spiro[indoline-3,2'-pyrrole]-2,5'(1'H)-diones and spiro[indoline-3,2'-pyrrolidine]-2,5'-diones, via a post-Ugi-domino transamidation/cyclization sequential process, has been achieved in three sequential steps utilizing a one-pot reaction
Amarendar Reddy Maddirala +1 more
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Synthesis and Antimicrobial Activity of Some New Sugar-Based Monocyclic β-Lactams
Molecules, 2004 The syntheses of some new sugar-based monocyclic β-lactams possessing several other functionalities in addition to the carbohydrate moiety are described.
A. Taslimi +2 more
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Advanced Functional Materials, EarlyView.Molecular rotors are fluorescent molecules that are sensitive to viscosity and temperature variations in the environment. They exhibit a direct correlation between fluorescence and viscosity within Newtonian fluids. However, this correlation becomes less straightforward in complex systems.
Flavia Di Scala +6 more
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Beilstein Journal of Organic Chemistry, 2013 The cis- and trans-stereoselective radical additions to α-methylene-γ-alkyl- γ-lactams were investigated and the scope and limitation of the reaction were also revealed.
Tomoko Yajima +2 more
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Chemistry of Bridged Lactams: Recent Developments
Molecules, 2019 Bridged lactams represent the most effective and wide-ranging method of constraining the amide bond in a non-planar conformation. A previous comprehensive review on this topic was published in 2013 (Chem. Rev. 2013, 113, 5701–5765).
Roman Szostak, Michal Szostak
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Tailored Diketopyrrolopyrrole Derivatives for Efficient Deep‐Red Organic Lasers
Advanced Functional Materials, EarlyView.Tailored diketopyrrolopyrrole derivatives exhibit high stable amplified spontaneous emission with single or dual bands. Incorporated into distributed‐feedback lasers based on one‐ and two‐dimensional dichromated‐gelatin diffractive gratings, these materials provide a robust, flexible platform for integrated organic deep‐red light sources. ABSTRACT Deep‐
Pablo Pasqués‐Gramage +10 more
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mBio, 2020 Poor penetration through the outer membrane (OM) of Gram-negative bacteria is a major barrier of antibiotic development. While β-lactam antibiotics are commonly used against Klebsiella pneumoniae and Enterobacter cloacae, there are limited data on OM ...
Tae Hwan Kim +19 more
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Trifluoroethanol Promoted Castagnoli–Cushman Cycloadditions of Imines with Homophthalic Anhydride
Molecules, 2022 Lactams are essential compounds in medicinal chemistry and key intermediates in the synthesis of natural products. The Castagnoli–Cushman reaction (CCR) of homophthalic anhydride with imines is an exciting method for accessing cyclic densely substituted ...
Thibault Bayles, Catherine Guillou
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