The Origins of Lactase Persistence in Europe
PLoS Computational Biology, 2009 Lactase persistence (LP) is common among people of European ancestry, but with the exception of some African, Middle Eastern and southern Asian groups, is rare or absent elsewhere in the world.
Yuval Itan, Mark G Thomas
exaly +11 more sources
A worldwide correlation of lactase persistence phenotype and genotypes [PDF]
BMC Evolutionary Biology, 2010 Background The ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that has been a subject of extensive genetic, medical and evolutionary research.
Ingram Catherine JE +4 more
doaj +5 more sources
Immobilization of enzymes for synergy in polymers to produce lactose free milk [PDF]
Scientific ReportsStabilization of the enzyme lactase is of interest in obtaining lactose-free foods. Optimization of the lactase enzyme activity was investigated using various immobilization methods, including encapsulation, and electrospinning.
Gayathri Peta +4 more
doaj +2 more sources
Not by Selection Alone: Expanding the Scope of Gene-Culture Coevolution. [PDF]
Evol AnthropolABSTRACT Gene‐culture coevolution (GCC)—an ambitious synthesis of biological and social sciences is often used to explain the evolution of key human traits. Despite the framework's broad conceptual appeal however, empirical evidence is often perceived as limited to a few key examples like lactase persistence.
Kasser SM +3 more
europepmc +2 more sources
World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection [PDF]
Human Genetics, 2017 The genetic trait of lactase persistence (LP) is associated with at least five independent functional single nucleotide variants in a regulatory region about 14 kb upstream of the lactase gene [-13910*T (rs4988235), -13907*G (rs41525747), -13915*G ...
Anke Liebert, Saioa López, Winston Lau
exaly +4 more sources
Simethicone Medication Should Be Avoided in Infants Receiving Oral Lactase Treatment [PDF]
ChildrenObjective: In this retrospective study, we assessed the efficacy of oral lactase in infants with lactose intolerance in terms of sex, birth weight, and interference by other medications.
Ekin Say Yildirim +5 more
doaj +2 more sources
Characterization of putative mannoprotein in Kluyveromyces lactis for lactase production
Synthetic and Systems Biotechnology, 2023 Lactase is a member of the β-galactosidase family of enzymes that can hydrolyze lactose into galactose and glucose. However, extracellular lactase production was still restricted to the process of cell lysis.
Xiuru Shen +5 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionThis study aimed to investigate the effects of Baohe pill decoction (BPD) on microbial, lactase activity, and lactase-producing bacteria in the intestinal mucosa of mice with diarrhea induced by high-fat and high-protein diet (HFHPD ...
Kang Zhou +4 more
doaj +1 more source
Ancient DNA analysis reveals high frequency of European lactase persistence allele (T-13910) in medieval central europe. [PDF]
PLoS ONE, 2014 Ruminant milk and dairy products are important food resources in many European, African, and Middle Eastern societies. These regions are also associated with derived genetic variants for lactase persistence.
Annina Krüttli +5 more
doaj +1 more source
The lactase persistence genotype is a protective factor for the metabolic syndrome [PDF]
Genetics and Molecular Biology, 2014 The Metabolic Syndrome (MetS) is defined as a pattern of metabolic disturbances, which include central obesity, insulin resistance and hyperglycemia, dyslipidemia, and hypertension.
Deise C. Friedrich +6 more
doaj +3 more sources