Results 31 to 40 of about 24,421 (251)

The pro sequence of lactase-phlorizin hydrolase is required for the enzyme to reach the plasma membrane An intramolecular chaperone? [PDF]

, 1993
Various cDNAs coding for part or all of human pre-pro lactase-phlorizin hydrolase (pre-proLPH) were transfected into COS cells and the subcellular location of the lactase-related proteins assessed.
Mantei, Ned, Oberholzer, Thomas, Semenza, Giorgio   +2 more
core   +1 more source

Lactase Deficiency and Lactose Intolerance: Current Understanding and Future Directions

Journal of Education, Health and Sport
Introduction and purpose: Lactose, the primary carbohydrate in milk, requires the enzyme lactase for digestion. Deficiency in lactase activity leads to lactose intolerance, causing gastrointestinal symptoms.
Krystian RACHWAŁ, Karol Wielgus, Piotr Bator, Wiktor Razik, Grzegorz Łyko, Maria Antos, Julia Furgalska, Maria Pawłowska, Angelika Wawryszuk   +8 more
doaj   +1 more source

Small intestinal development in suckling rats after enteral obestatin administration [PDF]

, 2018
This study investigated the effect of enteral administration of obestatin on the development of small intestine, as well as oxidative stress markers and trancriptomic profile of gastrointestinal genes. Suckling rats were assigned to 3 groups treated with:
Grzesiak, Paulina, Jank, Michał, Kato, Ikuo, Kowalczyk, Paweł, Kuwahara, Atsukazu, Majewska, Alicja, Rak, Agnieszka, Słupecka-Ziemilska, Monika, Woliński, Jarosław   +8 more
core   +1 more source

Lactosuria in the african with lactase deficiency [PDF]

The American Journal of Digestive Diseases, 1968
African subjects in Uganda with isolated lactase deficiency have a significant lactosuria after an oral lactose load. This can be detected by the Clinitest method, and probably has a value in screening African populations for lactase deficiency.
G. R. Howells, G. C. Cook
openaire   +3 more sources

Frequency of adult type-associated lactase persistence LCT-13910C/T genotypes in the Czech/Slav and Czech Roma/Gypsy populations

Genetics and Molecular Biology, 2017
Lactase non-persistence (leading to primary lactose intolerance) is a genetically dependent inability to digest lactose in adulthood. As part of the human adaptation to dairying, the human lactase LCT-13910C/T mutation (which propagates adult expression ...
Jaroslav A. Hubácek, Věra Adámková, Lenka Šedová, Věra Olišarová, Václav Adámek, Valérie Tóthová   +5 more
doaj   +1 more source

Measuring lactase enzymatic activity in the teaching lab [PDF]

, 2018
Understanding how enzymes work, and relating this to real life examples, is critical to a wide range of undergraduate degrees in the biological and biomedical sciences.
Cottrell, Graeme, Leksmono, Cattleya, Lewis, Patrick A, Lucchesi, Walter, Manzoni, Claudia, Tomkins, James   +5 more
core   +2 more sources

Role of High total protein in gallbladder bile in the formation of cholesterol gallstones. [PDF]

, 1991
While it is generally accepted that cholesterol supersaturation of bile is of key importance in the rapid formation of cholesterol crystals, the role of total biliary protein and pH in the pathogenesis of cholesterol gallstones is less well understood ...
Abell, Carey, Castell, Christoph von Ritter, Dieter Jüngst, Fiske, Gallinger, Gallinger, Groen, Groen, Gustav Paumgartner, Harvey, Harvey, Holan, Lanzini, Lee, Lee, Levy, Lowry, Magnuson, O'Donnel, Pearson, Podda, Sackmann, Sackmann, Sahlin, Sauerbruch, Sedaghat, Shiffman, Strasberg, Talalay, Tera, Thistle, Thomas Lang, Villanova, von Ritter, Yamazaki, Yu   +37 more
core   +1 more source

Association of the Lactase Persistence Haplotype Block With Disease Risk in Populations of European Descent

Frontiers in Genetics, 2020
Among people of European descent, the ability to digest lactose into adulthood arose via strong positive selection of a highly advantageous allele encompassing the lactase gene. Lactose-tolerant and intolerant individuals may have different disease risks
Shannon E. K. Joslin, Blythe P. Durbin-Johnson, Blythe P. Durbin-Johnson, Monica Britton, Matthew L. Settles, Ian Korf, Ian Korf, Danielle G. Lemay, Danielle G. Lemay, Danielle G. Lemay   +9 more
doaj   +1 more source

Production of HPMC-films for lactase administration [PDF]

Anais da Academia Brasileira de Ciências, 2020
The present work aimed to develop and characterize HPMC-films (HFs) based on hydroxypropylmethylcellulose (HPMC) with the addition of lactase for later application in the reduction of lactose in whole milk. The HFs were produced by the casting technique,
HELOÍSA R.P. DA SILVA, NATÁLIA STEVANATO, VITOR A.S. GARCIA, CAMILA DA SILVA   +3 more
doaj   +1 more source

World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection [PDF]

, 2017
The genetic trait of lactase persistence (LP) is associated with at least five independent functional single nucleotide variants in a regulatory region about 14 kb upstream of the lactase gene [-13910*T (rs4988235), -13907*G (rs41525747), -13915*G ...
A Kong, A Liebert, A Ranciaro, Anke Liebert, BL Jones, BL Jones, Bryony Leigh Jones, C Holden, CA Edmonds, CJ Ingram, CJ Ingram, CM Schlebusch, Dallas M. Swallow, E Priehodova, EJ Hollox, I Gallego Romero, I Mathieson, JP Didion, JT Troelsen, K Aoki, L Fang, L Odenthal-Hesse, L Segurel, LC Olds, M Coelho, M Poulter, M Stephens, M Stephens, Mark G. Thomas, ME Allentoft, N Maniatis, Neil Bradman, Nicolas Montalva, Nikolas Maniatis, NS Enattah, NS Enattah, OO Sverrisdottir, P Gerbault, P Gerbault, Pascale Gerbault, PC Sabeti, PC Sabeti, R Weston, S Klopfstein, S Myers, S Myles, SA Tishkoff, Saioa López, T Bersaglieri, TG Jensen, TS Plantinga, W Haak, Winston Lau, Y Itan, ZA Szpiech   +54 more
core   +5 more sources