Results 81 to 90 of about 25,062 (266)

Quantification of Information Gained by Linking Claims Data to an Electronic Health Record Cohort of Patients With Metastatic Breast Cancer

Pharmacoepidemiology and Drug Safety, Volume 34, Issue 10, October 2025.
ABSTRACT Purpose Linking claims data to electronic health record (EHR) data can improve completeness, often at a cost of decreased sample size. Quantifying information gained and differences in patient characteristics between EHR and EHR‐claims linked cohorts may inform study design.
Jonah Geddes, Julie Katz, Alex Asiimwe, M. Alan Brookhart, Charlotte Carroll, Lev Eldemir, Vera Mucaj, Kevin Nolan, Ioanna Ntalla, Carrie M. Nielson   +9 more
wiley   +1 more source

Lactase Immobilized on Alumina

Journal of Dairy Science, 1980
Abstract A commercial neutral lactase ( kluyveromyces lactis was immobilized on inexpensive alumina activated with tolylene-2,4-diisocyanate. Heat treatment of the alumina at 500C for 48h was effective in promoting the tolylene-2,4-diisocyanate reaction with its surface.
T. Finocchiaro, T. Richardson, Norman F. Olson   +2 more
openaire   +2 more sources

Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase phlorizin hydrolase [PDF]

FEBS Letters, 2000
Lactase phlorizin hydrolase (LPH; EC 3.2.1.62) is a membrane‐bound, family 1 β‐glycosidase found on the brush border of the mammalian small intestine. LPH, purified from sheep small intestine, was capable of hydrolysing a range of flavonol and isoflavone glycosides.
Andrea J. Day, Gary Williamson, Juan C Dı́az, Craig B. Faulds, F. Javier Cañada, Geoff W. Plumb, Russell Mclauchlan, Paul A. Kroon, Michael R. A. Morgan   +8 more
openaire   +3 more sources

In vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayer

Nutrition Journal, 2005
Background Quercetin and quercetin glycosides are widely consumed flavonoids found in many fruits and vegetables. These compounds have a wide range of potential health benefits, and understanding the bioavailability of flavonoids from foods is becoming ...
Brown Dan, Boyer Jeanelle, Liu Rui
doaj   +1 more source

Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis [PDF]

, 1999
KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K.
CRISA A., FALCONE, Claudio, FLEER R., JUNG G., MAZZONI, Cristina, SALIOLA, Michele, SOLIMANDO N.   +6 more
core  

Safety evaluation of the food enzyme containing β‐fructofuranosidase and β‐glucosidase activities from the non‐genetically modified Aspergillus tubingensis strain IN 319

EFSA Journal, Volume 23, Issue 10, October 2025.
Abstract The food enzyme containing β‐fructofuranosidase (β‐d‐fructofuranoside fructohydrolase; EC 3.2.1.26) and β‐glucosidase (β‐d‐glucoside glucohydrolase; EC 3.2.1.21) activities is produced with the non‐genetically modified Aspergillus tubingensis strain IN 319 by Shin Nihon Chemical Co., Ltd.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Ana Criado, Jaime Aguilera, Magdalena Andryszkiewicz, Daniele Cavanna, Cristina Fernández‐Fraguas, Yi Liu   +18 more
wiley   +1 more source

Bioequivalence of a Donepezil/Memantine 10/20 mg Fixed‐Dose Combination Versus Single‐Component Tablets in Healthy Korean Males

Clinical Pharmacology in Drug Development, Volume 14, Issue 9, Page 710-716, September 2025.
Abstract A fixed‐dose combination (FDC) tablet formulation of donepezil/memantine (10/20 mg) was developed to improve medication compliance in patients with Alzheimer's disease (AD). This study compared the pharmacokinetic (PK) characteristics and safety profiles of an FDC formulation (donepezil/memantine [10/20 mg]) and single components (SCs) of ...
Minkyu Choi, Byung Hak Jin, Do Hoon Keum, Kyoung Hoon Mo, Min Soo Park, Juhwan Lee, Sungjin Park, Choon Ok Kim   +7 more
wiley   +1 more source

LACTASE DEFICIENCY IN CHILDREN

Педиатрическая фармакология, 2011
The topic of the article is the lactase deficiency in children. The most frequent clinical manifestations — diarrhea and flatulence —are not specific to this pathology. Symptoms, typical for the majority of the diseases nosologies of the digestive system,
V.A. Shcherbak, N.M. Shcherbak
doaj   +2 more sources

Genomic Nutritional Profiling:Innovation and Regulation in Nutrigenomics [PDF]

, 2007
Castle, David. (2007). Genomic Nutritional Profiling: Innovation and Regulation in Nutrigenomics.
Castle, David
core   +1 more source

Specific responses in rat small intestinal epithelial mRNA expression and protein levels during chemotherapeutic damage and regeneration [PDF]

, 2002
The rapidly dividing small intestinal epithelium is very sensitive to the cytostatic drug methotrexate. We investigated the regulation of epithelial gene expression in rat jejunum during methotrexate-induced damage and regeneration. Ten
Büller, H.A. (Hans), Dekker, J. (Jan), Einerhand, A.W.C. (Sandra), Ferdinandusse, S., Jorritsma, M., Nispen, D.J. van, Renes, I.B. (Ingrid), Verburg, M. (Melissa)   +7 more
core   +2 more sources