Results 41 to 50 of about 896,464 (230)

Diagnostic possibilities of lactase deficiency in children with cystic fibrosis

Russian Pediatric Journal, 2021
Introduction. Children with cystic fibrosis often have gastrointestinal symptoms despite properly selected primary therapy and pancreatic substitution therapy. A possible reason is lactase deficiency.
E. Roslavtseva, I. Sokolov, O. Simonova, T. Bushueva, T. Borovik, I. E. Smirnov, V. Chernevich, M. M. Lokhmatov   +7 more
semanticscholar   +1 more source

The Incidence of Functional Disorders and Clinical Symptoms that May be Associated with Lactase Deficiency in Infants of Lviv

Zdorovʹe Rebenka, 2016
Today, the violations of the digestive system in children of the first years of life remain the actual problem of practical pediatrics and are the common cause for parents to visit a doctor.
R.V. Tkach, S.L. Nyankovskyy, O.S. Nyankovska, M.S. Yatsula   +3 more
doaj   +1 more source

The use of lactase in the relief of chronic diarrhea syndrome in children

Zdorovʹe Rebenka, 2020
The article deals with one of the most urgent problems of pediatrics — malassimilation syndrome due to lactose intolerance in children at different age periods.
L.G. Voloshyna, O.Yu. Belousova, O.M. Вabadzhanian, N.V. Pavlenko, I.G. Solodovnichenko, O.V. Shutova, K.V. Voloshyn, O.B. Hanzii, K.V. Savytska, A.M. Kaafarani, O.L. Slobodianiuk   +10 more
doaj   +1 more source

Disaccharidase deficiency and functional bowel diseases [PDF]

Терапевтический архив, 2017
Aim. To elucidate the role of intestinal carbohydrases (glucoamylase, maltase, sucrose, and lactase) in the etiology and pathogenesis of functional bowel diseases (FBD). Subjects and methods. 74 patients (36 men and 38 women) aged 18 to 50 years with FBD
A I Parfenov, O V Akhmadullina, E A Sabelnikova, N I Belostotsky, M V Kirova, S G Khomeriki, S V Bykova   +6 more
doaj   +1 more source

Laboratory signs of carbohydrate malabsorption in early age children with rotavirus infection

Patologìâ, 2021
The aim – to determine the laboratory manifestations of carbohydrate malabsorption syndrome in the dynamics of rotavirus infection in early age children and to identify the factors that influence its severity. Materials and methods. The study included
N. V. Vorobiova, O. V. Usachova
doaj   +1 more source

Novel Role of Gut-Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure. [PDF]

Adv Sci (Weinh)
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Zhou L, Wang C, Gao J, Wu X, Li G, Jiang X, Xia Y, Zhang J, Lv B, Zhao F, Zhang H, Pi H, Qiu J, Xu S, Zou Z, Chen C.   +15 more
europepmc   +2 more sources

Molecular and cellular analysis of intestinal lactase‐phlorizin hydrolase gene variants unravel a heterogeneous pathogenic pattern of congenital lactase deficiency

The FASEB Journal, 2020
Congenital lactase deficiency (CLD) is a rare autosomal recessive genetic disorder, leading to a dysfunctional lactase‐phlorizin hydrolase (LPH). LPH is a ß‐galactosidase located in the intestinal brush border membrane and indispensable for lactose ...
Lara M. Marten, D. Wanes, R. Santer, H. Naim   +3 more
semanticscholar   +1 more source

Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited

World Allergy Organization Journal, 2017
Lactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be absorbed.
Ralf G. Heine, Fawaz AlRefaee, Prashant Bachina, Julie C. De Leon, Lanlan Geng, Sitang Gong, José Armando Madrazo, Jarungchit Ngamphaiboon, Christina Ong, Jossie M. Rogacion   +9 more
doaj   +3 more sources

Gastrointestinal disorders in secondary lactase deficiency: diagnostic features, methods of correction

Modern pediatrics. Ukraine
A modern problem of practical pediatrics is secondary lactase deficiency - intolerance to dairy products containing lactose, which develops in response to a decrease in lactase activity due to enterocyte damage in an infectious, allergic, or other ...
Y. Marushko, T. Marushko, O. Dmytryshyn, T. Iovitsa, O.A. Bovkun   +4 more
semanticscholar   +1 more source

PERCC1‐associated enteropathy: Diagnostic challenges and enteral autonomy achieved with teduglutide

JPGN Reports, EarlyView.
Abstract Congenital diarrheas and enteropathies (CODE) are rare inherited disorders characterized by early‐onset intractable diarrhea. Though progress has been made in elucidating the genetic basis of CODE, much remains to be discovered. Another challenge is the lack of curative therapies—treatment is primarily supportive including enteral and ...
Angela Tran, Vivien Nguyen, Phuong Huynh
wiley   +1 more source