The Phenotype/Genotype Correlation of Lactase Persistence among Omani Adults [PDF]
Oman Medical Journal, 2013 Objective: To examine the correlation of lactase persistence phenotype with genotype in Omani adults.Methods: Lactase persistence phenotype was tested by hydrogen breath test in 52 Omani Adults using the Micro H2 analyzer.
Abdulrahim Al-Abri, Riad Bayoumi
doaj +2 more sources
Human Genetics: Lactase Persistence in a Battlefield [PDF]
Current Biology, 2020 Lactase persistence is a common genetic trait in Europeans and other pastoralists. New ancient DNA evidence from a Bronze Age battlefield indicates that selection for lactase persistence was strong and on-going in the last 3,000 ...
Saag, L
core +5 more sources
Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals [PDF]
Scientific Reports, 2018 In humans the expression of lactase changes during post-natal development, leading to phenotypes known as lactase persistence and non-persistence. Polymorphisms within the lactase gene (LCT) enhancer, in particular the −13910C > T, but also others, are ...
Milena N. Leseva +6 more
doaj +6 more sources
Lactase persistence, NOD2 status and
Gut Pathogens, 2012 Background Inflammatory Bowel Disease (IBD), which includes both Crohn’s disease (CD) and ulcerative colitis (UC), is caused by a complex interplay involving genetic predisposition, environmental factors and an infectious agent. Mycobacterium avium subsp.
Elguezabal Natalia +6 more
doaj +2 more sources
Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non‐persistence polymorphism [PDF]
Annals of Human Genetics, 1998 A genetic polymorphism is responsible for determining that some humans express lactase at high levels throughout their lives and are thus lactose tolerant, while others lose lactase expression during childhood and are lactose intolerant. We have previously shown that this polymorphism is controlled by an element or elements which act in cis to the ...
Clare B. Harvey +11 more
openalex +7 more sources
Food & FunctionLactase persistence is a genetically inherited trait that enables continued lactose digestion into adulthood. Lactase non-persistence (LNP) individuals often experience incomplete lactose digestion, allowing undigested lactose to reach the colon, where ...
Yirui Tang +6 more
openalex +2 more sources
New insights into the history of the C-14010 lactase persistence variant in Eastern and Southern Africa. [PDF]
Am J Phys Anthropol, 2015 Macholdt E +3 more
europepmc +3 more sources
Lactase non-persistence and milk consumption in Estonia
World Journal of Gastroenterology, 2006 To define the frequency of the C/T-13910 variant associated with lactase persistence/non-persistence trait and to analyze the milk consumption of lactase non-persistent subjects in Estonia.We genotyped 355 Estonians by polymerase chain reaction and direct sequencing.
Margus Lember
openalex +3 more sources
Cystic Fibrosis: Cystic fibrosis and lactase persistence: a possible correlation [PDF]
European Journal of Human Genetics, 2006 C ystic fibrosis (CF) is the most common lethal genetic disease in Europeans and is transmitted as an autosomal recessive disorder caused by loss of function of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. Since long it has been supposed that its quite high frequency (1/ 2500 implying an allele frequency equal to 0.02) is due to
G. Modiano +2 more
openalex +5 more sources