Results 61 to 70 of about 334,943 (248)

Lactose Intolerance: Common Misunderstandings [PDF]

, 2019
Lactose intolerance primarily refers to a syndrome having different symptoms upon the consumption of foods containing lactose. It is one of the most common form of food intolerance and occurs when lactase activity is reduced in the brush border of the ...
Berni Canani, Roberto, Di Costanzo, Margherita   +1 more
core   +1 more source

Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment [PDF]

, 2010
Clinical manifestations of lactase (LCT) deficiency include intestinal and extra-intestinal symptoms. Lactose hydrogen breath test (H2-BT) is considered the gold standard to evaluate LCT deficiency (LD).
A. v. Eckardstein, B. Stutz, D. Pohl, E. Savarino, Hertzler, Kirschner, Krawczyk, M. Fried, M. Hersberger, Naim, O. Goetze, R. Tutuian, Savaiano, Z. Behlis   +13 more
core   +3 more sources

The human lactase persistence-associated SNP −13910*T enables in vivo functional persistence of lactase promoter–reporter transgene expression [PDF]

Human Genetics, 2012
Lactase is the intestinal enzyme responsible for digestion of the milk sugar lactose. Lactase gene expression declines dramatically upon weaning in mammals and during early childhood in humans (lactase nonpersistence). In various ethnic groups, however, lactase persists in high levels throughout adulthood (lactase persistence).
Lin, Fang, Jong Kun, Ahn, Dariusz, Wodziak, Eric, Sibley   +3 more
openaire   +2 more sources

Laktózintolerancia: a laktázgén C/T-13910 polimorfizmusának és a hidrogénkilégzési teszt pontosságának retrospektív kiértékelése gasztroenterológiai szakrendelésen [PDF]

, 2016
Absztrakt Bevezetés: A felnőtt típusú hypolactasia a leggyakoribb szénhidrát-felszívódási zavar. Célkitűzés: A laktázgén C/T-13910-polimorfizmus eloszlásának és a H2-kilégzési teszt
Buzás, György, Csókay, Béla, Fodor, Flóra   +2 more
core   +1 more source

Differences in DNA Methylation and Functional Expression in Lactase Persistent and Non-persistent Individuals

Scientific Reports, 2018
In humans the expression of lactase changes during post-natal development, leading to phenotypes known as lactase persistence and non-persistence. Polymorphisms within the lactase gene (LCT) enhancer, in particular the −13910C > T, but also others, are ...
Milena N. Leseva, Richard J. Grand, Hagen Klett, Melanie Boerries, Hauke Busch, Alexandra M. Binder, Karin B. Michels   +6 more
doaj   +1 more source

Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited

World Allergy Organization Journal, 2017
Lactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be absorbed.
Ralf G. Heine, Fawaz AlRefaee, Prashant Bachina, Julie C. De Leon, Lanlan Geng, Sitang Gong, José Armando Madrazo, Jarungchit Ngamphaiboon, Christina Ong, Jossie M. Rogacion   +9 more
doaj   +3 more sources

Association between increased plasma levels of homocysteine and depression observed in individuals with primary lactose malabsorption. [PDF]

PLoS ONE, 2018
BACKGROUND:Current literature proposes associations between homocysteine (HCY), folic acid (FA), vitamin B12 metabolism and depression. However, the exact underlying biological mechanisms remain unclear.
Dietmar Enko, Andreas Meinitzer, Wolfgang Brandmayr, Gabriele Halwachs-Baumann, Wolfgang J Schnedl, Gernot Kriegshäuser   +5 more
doaj   +1 more source

Meta-analysis of lactase phenotypes on obesity, metabolic syndrome and milk consumption

BMJ Nutrition, Prevention & Health
Background The variability in lactose digestion ability is categorised into lactase persistence and lactase non-persistence phenotypes, primarily determined by the 13 910 C>T single nucleotide polymorphism (rs4988235).
Pornthep Tanpowpong, Sasivimol Rattanasiri, Karis Phengsalae, Songpon Getsuwan, Sirinapa Siwarom   +4 more
doaj   +1 more source

Evaluation of Milk and Lactose Sensitivity in Lactase Non-Persistence Genotypes

Proceedings, 2019
Background: Lactase non-persistence, a condition affecting 75% of the world’s population, ischaracterized by inactivity of the lactase enzyme, resulting in lactose intolerance. [...]
Aahana Shrestha, Jakob André Martinsson, Helga Josefin Karlström, Nils Jimmy Nilsson, Mathew Philip Greig Barnett, Jo Kate Perry, Amber Marie Milan, David Cameron-Smith   +7 more
doaj   +1 more source

Grappling with Diversity in Livestock-Related, Non-Agriculturist Archaeology in the Light of Genetic Research into the Lactase Persistence Allele, -14010*C, in Southern Africa

Africa, the Cradle of Human Diversity, 2021
The paper by Breton et al. (2014) demonstrating a shared ancestry between an eastern Africa population and the Khoe-speaking Nama of southern Africa has freed archaeologists to consider once again the place of demic diffusion in the spread of the first ...
Thembi Russell, Faye Lander
semanticscholar   +1 more source