Lactose Intolerance: Common Misunderstandings [PDF]
Lactose intolerance primarily refers to a syndrome having different symptoms upon the consumption of foods containing lactose. It is one of the most common form of food intolerance and occurs when lactase activity is reduced in the brush border of the ...
Berni Canani, Roberto +1 more
core +1 more source
The ability to digest milk during adulthood (lactase persistence) is a genetically determined trait present only in humans. Its origin and diffusion are correlated with the development of pastoralism and the consumption of fresh milk.
Michela Leonardi
doaj +1 more source
Genetic diversity of lactase persistence in East African populations. [PDF]
The expression of lactase which digests lactose from milk in humans is generally lost after weaning, but selected mutations influencing the promoter of the lactase gene have spread into the human populations. This is considered a classical example of gene-culture co-evolution, and several studies suggested that the lactase gene has been under strong ...
Hassan HY +6 more
europepmc +7 more sources
Association of the rs4988235 in the lactase gene with obesity and its modulation by dairy products in a Mediterranean population [PDF]
The -13910C>T polymorphism (rs4988235) upstream from the lactase (LCT) gene, strongly associated with lactase persistence (LP) in Europeans, is emerging as a new candidate for obesity. We aimed to analyze the association of this polymorphism with obesity-
Arregui, María +9 more
core +2 more sources
Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. [PDF]
Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans.
Deise C Friedrich +3 more
doaj +1 more source
Evolution of the human fear-circuitry and acute sociogenic pseudoneurological symptoms: The Neolithic balanced-polymorphism hypothesis [PDF]
In light of the increasing threat of large-scale massacres such as terrorism against non-combatants (civilians), more attention is warranted not only to posttraumatic stress disorder (PTSD) but also to acute sociogenic pseudoneurological ("conversion ...
Bracha, Dr. H. Stefan +3 more
core +1 more source
Association of lactase persistence genotype with milk consumption, obesity and blood pressure:a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort with a systematic review and meta-analysis. [PDF]
Background: Milk intake has been associated with lower blood pressure (BP) in observational studies, and randomized controlled trials suggested that milk-derived tripeptides have BP-lowering effects.
Davey Smith, George +4 more
core +1 more source
Measuring lactase enzymatic activity in the teaching lab [PDF]
Understanding how enzymes work, and relating this to real life examples, is critical to a wide range of undergraduate degrees in the biological and biomedical sciences.
Cottrell, Graeme +5 more
core +2 more sources
Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment [PDF]
Clinical manifestations of lactase (LCT) deficiency include intestinal and extra-intestinal symptoms. Lactose hydrogen breath test (H2-BT) is considered the gold standard to evaluate LCT deficiency (LD).
A. v. Eckardstein +13 more
core +3 more sources
Laktózintolerancia: a laktázgén C/T-13910 polimorfizmusának és a hidrogénkilégzési teszt pontosságának retrospektív kiértékelése gasztroenterológiai szakrendelésen [PDF]
Absztrakt Bevezetés: A felnőtt típusú hypolactasia a leggyakoribb szénhidrát-felszívódási zavar. Célkitűzés: A laktázgén C/T-13910-polimorfizmus eloszlásának és a H2-kilégzési teszt
Buzás, György +2 more
core +1 more source

