Results 1 to 10 of about 399,558 (149)

Lactate and intestinal fatty acid binding protein as essential biomarkers in neonates with necrotizing enterocolitis: ultrasonographic and surgical considerations

Pediatrics and Neonatology, 2020
Background: Necrotizing enterocolitis (NEC) is a neonatal disease with its pathogenesis still not well understood, although it is hypothesized to be related to decreased perfusion of the intestinal wall.
Ahmed El-Abd Ahmed, Mohammed H. Hassan, Nezar Abo-Halawa, Ghada M. Abdel-Razik, Fatma A. Moubarak, Hala M. Sakhr   +5 more
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Hydroxycarboxylic Acid Receptor 1 and Neuroprotection in a Mouse Model of Cerebral Ischemia-Reperfusion

Frontiers in Physiology, 2021
Lactate is an intriguing molecule with emerging physiological roles in the brain. It has beneficial effects in animal models of acute brain injuries and traumatic brain injury or subarachnoid hemorrhage patients.
Lara Buscemi, Lara Buscemi, Camille Blochet, Camille Blochet, Pierre J. Magistretti, Lorenz Hirt, Lorenz Hirt   +6 more
doaj   +1 more source

Rewiring of Glucose and Lipid Metabolism Induced by G Protein-Coupled Receptor 17 Silencing Enables the Transition of Oligodendrocyte Progenitors to Myelinating Cells

Cells, 2022
In the mature central nervous system (CNS), oligodendrocytes (OLs) provide support and insulation to axons thanks to the production of a myelin sheath. During their maturation to myelinating cells, OLs require energy and building blocks for lipids, which
Davide Marangon, Matteo Audano, Silvia Pedretti, Marta Fumagalli, Nico Mitro, Davide Lecca, Donatella Caruso, Maria P. Abbracchio   +7 more
doaj   +1 more source

Evaluating the Possibility of Translating Technological Advances in Non-Invasive Continuous Lactate Monitoring into Critical Care

Sensors, 2021
Lactate is widely measured in critically ill patients as a robust indicator of patient deterioration and response to treatment. Plasma concentrations represent a balance between lactate production and clearance. Analysis has typically been performed with
Robert D. Crapnell, Ascanio Tridente, Craig E. Banks, Nina C. Dempsey-Hibbert   +3 more
doaj   +1 more source

Effects of Lactate Administration on Mitochondrial Respiratory Function in Mouse Skeletal Muscle

Frontiers in Physiology, 2022
Recent evidence has shown that mitochondrial respiratory function contributes to exercise performance and metabolic health. Given that lactate is considered a potential signaling molecule that induces mitochondrial adaptations, we tested the hypothesis ...
Kenya Takahashi, Yuki Tamura, Yuki Tamura, Yu Kitaoka, Yutaka Matsunaga, Hideo Hatta   +5 more
doaj   +1 more source

Effect of fish oil and canola oil supplementation on immunological parameters, feed intake, and growth of Holstein calves

Journal of Dairy Science, 2022
: Supplemental n-3 fatty acids (FA) may support better immune responses than n-6 and n-9 FA in dairy calves. The objective was to evaluate the effect of n-3 FA, supplemented as a fish oil product (FO) in the milk replacer (MR), in comparison to n-6 and n-
P. Melendez, C.F. Roeschmann, A. Baudo, S. Tao, P. Pinedo, A. Kalantari, M. Coarsey, J.K. Bernard, H. Naikare   +8 more
doaj   +1 more source

Insulin gene expression and functional activity of insulin signaling pathway in Alzheimer's disease

Фундаментальная и клиническая медицина, 2021
Aim. To study the insulin (INS) gene expression, insulin and lactate levels, expression of Fe65 adapter protein, and level of oxidative DNA damage marker γH2AX in different brain areas in the experimental model of Alzheimer's disease.Materials and ...
Y. V. Gorina, E. D. Khilazheva, Yu. K. Komleva, O. L. Lopatina, A. B. Salmina   +4 more
doaj   +1 more source

Role of Lactate in Inflammatory Processes: Friend or Foe

Frontiers in Immunology, 2022
During an inflammatory process, shift in the cellular metabolism associated with an increase in extracellular acidification are well-known features. This pH drop in the inflamed tissue is largely attributed to the presence of lactate by an increase in ...
Carolina Manosalva, John Quiroga, John Quiroga, Alejandra I. Hidalgo, Pablo Alarcón, Nicolás Ansoleaga, Nicolás Ansoleaga, María Angélica Hidalgo, Rafael Agustín Burgos   +8 more
doaj   +1 more source

Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window [PDF]

Journal of Exercise & Organ Cross Talk
Dear Editor-in-ChiefWith the alarming rise in cancer cases, which is now recognized as the leading cause of death, the importance of exercise in cancer management is gaining significant recognition (Ahmadi Hekmatikar et al., 2023).
Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani   +2 more
doaj   +1 more source

The effects of acute exercise applied to the lower extremity with blood flow restriction on perceived exertion, blood lactate level and cardiovascular responses

ROL Spor Bilimleri Dergisi, 2023
This study, it was aimed to compare the effects of acute squat exercise applied to the lower extremities with and without blood flow restriction (BFR) on post-exercise cardiovascular responses, blood lactate level and perceived exercise intensity.
Seda Yalcin
doaj   +1 more source