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Recent evidence from cancer research indicates that lactate exerts a suppressive effect on innate immune responses in cancer. This study investigated the mechanisms by which lactate suppresses macrophage pro-inflammatory responses. Macrophages [Raw 264.7
Min Fan, Tuanzhu Ha, Chuanfu Li
exaly +3 more sources
BackgroundCentral venous pressure (CVP) monitoring is widely used in the intensive care unit (ICU). However, the formal utility of CVP measurement to altering patient outcomes among ICU patients with or at risk for acute respiratory distress syndrome ...
Rui Tang, Junnan Peng, Daoxin Wang
doaj +1 more source
Analysis of lactation shapes in extended lactations [PDF]
In order to describe the temporal evolution of milk yield (MY) and composition in extended lactations, 21 658 lactations of Italian Holstein cows were analyzed. Six empirical mathematical models currently used to fit 305 standard lactations (Wood, Wilmink, Legendre, Ali and Schaeffer, quadratic and cubic splines) and one function developed specifically
Roberto Steri+4 more
openaire +4 more sources
Brewers’ spent grains (BSG) are a by-product of the brewing industry that is mainly used as feedstock; otherwise, it has to be disposed according to regulations.
Blanka Didak Ljubas+9 more
doaj +1 more source
Lactate can be produced by many gut bacteria, but in adults its accumulation in the colon is often an indicator of microbiota perturbation. Using continuous culture anaerobic fermentor systems, we found that lactate concentrations remained low in ...
Shui Ping Wang+11 more
doaj +1 more source
Risk factors for persistent elevation of perioperative lactate levels in gastric cancer surgery
Background: The impact of high-risk surgery on tissue perfusion can be indirectly assessed by measuring lactate levels during surgery and intensive care unit (ICU) stay.
Selcuk Gulmez +9 more
doaj +1 more source
Clinical observations of Leber hereditary optic neuropathy with and without neurological symptoms [PDF]
Three case studies of adults with Leber hereditary optic neuropathy with and without neurological symptoms are presented. An elevated blood lactate level and changes in the activity of the mitochondrial enzymes in peripheral blood lymphocytes were noted.
Sergey V. Kotov+4 more
doaj +1 more source
Crosstalk Between Staphylococcus aureus and Innate Immunity: Focus on Immunometabolism
Staphylococcus aureus is a leading cause of bacterial infections globally in both healthcare and community settings. The success of this bacterium is the product of an expansive repertoire of virulence factors in combination with acquired antibiotic ...
Christopher M. Horn, Tammy Kielian
doaj +1 more source
Objectives: Ewing sarcoma (EWS) is an aggressive tumor of bone and soft tissue. Growing evidence indicated lactate as a pivotal mediator of crosstalk between tumor energy metabolism and microenvironmental regulation.
Zhao Zhang+8 more
doaj +1 more source