Results 51 to 60 of about 708,087 (381)

Tetracycline and Lactation

open access: yesThe Journal of the American Dental Association, 1983
The Journal of the American Dental Association 107 (1983) 12,14-12,14.
UNIVERSITY OF FLORIDA, GAINESVILLE, FLAUNIVERSITY OF FLORIDAGAINESVILLEFLA ( host institution )   +2 more
openaire   +4 more sources

TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer. [PDF]

open access: yes, 2016
A subgroup of breast cancers has several metabolic compartments. The mechanisms by which metabolic compartmentalization develop in tumors are poorly characterized. TP53 inducible glycolysis and apoptosis regulator (TIGAR) is a bisphosphatase that reduces
Bartrons, Ramon   +15 more
core   +2 more sources

Biochemical scenario behind initiation of diabetic retinopathy in type 2 diabetes mellitus

open access: yesIndian Journal of Ophthalmology, 2018
Purpose: Despite the disease having similar glycemic status and duration microangiopathy in some patients develop within few years whereas it doesn't appear as a health complication in some diabetics for a considerable period. This study is undertaken to
Lakshmi Kanta Mondal   +2 more
doaj   +1 more source

Acute metabolic effects of tonic‐clonic seizures

open access: yesEpilepsia Open, 2019
Objective Tonic‐clonic seizures (TCS) lead to metabolic stress and changes in related blood markers. Such markers may indicate harmful conditions but can also help to identify TCS as a cause of transient loss of consciousness.
Robert D. Nass   +4 more
doaj   +1 more source

Mutual regulation of lactate dehydrogenase and redox robustness

open access: yesFrontiers in Physiology, 2022
The nature of redox is electron transfer; in this way, energy metabolism brings redox stress. Lactate production is associated with NAD regeneration, which is now recognized to play a role in maintaining redox homeostasis.
Yijun Lin, Yan Wang, Pei-feng Li
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective [PDF]

open access: yesBMC Systems Biology 7:103 (2013), 2013
The energetics of cerebral activity critically relies on the functional and metabolic interactions between neurons and astrocytes. Important open questions include the relation between neuronal versus astrocytic energy demand, glucose uptake and intercellular lactate transfer, as well as their dependence on the level of activity.
arxiv   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A heuristic approach for lactate threshold estimation for training decision-making: An accessible and easy to use solution for recreational runners [PDF]

open access: yes, 2019
In this work, a heuristic as operational tool to estimate the lactate threshold and to facilitate its integration into the training process of recreational runners is proposed. To do so, we formalize the principles for the lactate threshold estimation from empirical data and an iterative methodology that enables experience based learning. This strategy
arxiv   +1 more source

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