Results 81 to 90 of about 708,087 (381)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

The Particularities of Nonspecific Stress Resistance Mechanism Activation in Baikalian Endemic Amphipod Gmelinoides fasciatus (Stebb, 1899) under Thermal Stress [PDF]

Journal of Stress Physiology & Biochemistry, 2014
The aim of the current study was to determine the characteristics of the stress response in endemic species Gmelinoides fasciatus (Stebb., 1899) in comparison with other Baikal amphipods under short term thermal stress.
Vereshchagina K.P., Lubyaga Y.A., Axenov-Gribanov D.V., Gurkov A.N., Kondratieva E.S., Shchapova E.P., Prokosov S.O., Shatilina Z.M.   +7 more
doaj  

Biochemical Effects of Carbohydrate Supplementation in a Simulated Competition of Short Terrestrial Duathlon

Journal of the International Society of Sports Nutrition, 2006
The purpose of the present study was to investigate the biochemical effects of carbohydrate supplementation in a simulated competition of short terrestrial duathlon.
Campbell Bill, Kreider Richard, dos Santos Maria, Mamus Renata   +3 more
doaj   +1 more source

Lactate Oxidation in Endothelial Cells: A Feature of All Endothelial Cells? [PDF]

, 2019
Resumen de la comunicaciónMetabolism of endothelial cells is a topic that has gained an increasing interest in the last years. This is due to their role in the angiogenic process, which is pathologically upregulated in several diseases, such as ...
Martínez-Poveda, Beatriz, Medina, Miguel Ángel, Ocaña-Ocaña, Maria del Carmen, Quesada, Ana R.   +3 more
core  

Investigation of nanofiltration as a purification step for lactic acid production processes based on conventional and bipolar electrodialysis operations [PDF]

, 2006
Nanofiltration was investigated for usability in a specific lactic acid production process based on conventional and bipolar electrodialysis operations.
Bouchoux, Antoine, Lutin, Florence, Roux-de Balmann, Hélène   +2 more
core   +2 more sources

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

A Novel Metabolic Reprogramming Strategy for the Treatment of Diabetes‐Associated Breast Cancer

Advanced Science, 2022
Diabetes is directly related to the risk of breast cancer (BC) occurrence and worsened BC prognosis. Currently, there are no specific treatments for diabetes‐associated BC.
Qiongyu Hao, Zhimin Huang, Qun Li, Dingxie Liu, Piwen Wang, Kun Wang, Jieqing Li, Wei Cao, Wenhong Deng, Ke Wu, Rui Su, Zhongmin Liu, Jay Vadgama, Yong Wu   +13 more
doaj   +1 more source

Production processes of fermented organic acids targeted around membrane operations: design of the concentration step by conventional electrodialysis [PDF]

, 2001
Organic acids are increasingly used for various industrial applications. Their production is mainly achieved by fermentation. Precipitation or extraction stages, which generate big amount of effluents, are then traditionally used to get the acid in a ...
Aimar, Pierre, Bailly, Mathieu, Cheryan, Munir, Lutin, Florence, Roux-de Balmann, Hélène   +4 more
core   +2 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Use of an audio-paced incremental swimming test in young national-level swimmers [PDF]

, 2008
Purpose:To evaluate the reliability and sensitivity to training of an audio-paced incremental swimming test.Methods:Eight young national-level male swimmers (age 15 ± 1 year) performed a 7 × 200-m incremental swimming test (velocities 1.19, 1.24, 1.28, 1.
Coleman, Simon G S, Smith, Taylor, Turner, Anthony P   +2 more
core   +1 more source