Results 11 to 20 of about 209,396 (337)
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
wiley +1 more source
Effects of brake wear nanoparticles on the protection and repair functions of the airway epithelium [PDF]
Environmental pollution 327, 121554 (2023), 2023 Long term exposure to particulate air pollution is known to increase respiratory morbidity and mortality. In urban areas with dense traffic most of these particles are generated by vehicles, via engine exhaust or wear processes. Non-exhaust particles come from wear processes such as those concerning brakes and their toxicity is little studied.
arxiv +1 more source
Microbiome, 2022 Background Intestinal inflammation disrupts the microbiota composition leading to an expansion of Enterobacteriaceae family members (dysbiosis). Associated with this shift in microbiota composition is a profound change in the metabolic landscape of the ...
Savannah J. Taylor +14 more
doaj +1 more source
Prediction of Blood Lactate Values in Critically Ill Patients: A Retrospective Multi-center Cohort Study [PDF]
J Clin Monit Comput. 2021 PMID: 34224051, 2021 Purpose. Elevations in initially obtained serum lactate levels are strong predictors of mortality in critically ill patients. Identifying patients whose serum lactate levels are more likely to increase can alert physicians to intensify care and guide them in the frequency of tending the blood test.
arxiv +1 more source
Expression of lactate dehydrogenase C correlates with poor prognosis in renal cell carcinoma
Tumor Biology, 2017 Lactate dehydrogenase C is an isoenzyme of lactate dehydrogenase and a member of the cancer–testis antigens family. In this study, we aimed to investigate the expression and functional role of lactate dehydrogenase C and its basic mechanisms in renal ...
Yibo Hua +12 more
doaj +1 more source
Incorporating expression data in metabolic modeling: a case study of lactate dehydrogenase [PDF]
J Theor Biol 240: 464-474 (2006), 2005 Integrating biological information from different sources to understand cellular processes is an important problem in systems biology. We use data from mRNA expression arrays and chemical kinetics to formulate a metabolic model relevant to K562 erythroleukemia cells. MAP kinase pathway activation alters the expression of metabolic enzymes in K562 cells.
arxiv +1 more source
The utility of lactate dehydrogenase in the follow up of patients with diffuse large B-cell lymphoma
Revista Brasileira de Hematologia e Hemoterapia, 2013 Background: Serum lactate dehydrogenase is a non-specific marker for lymphoma whose prognostic significance is well established for both indolent and aggressive lymphomas at the time of diagnosis.
Basem Magdy William +6 more
doaj +1 more source
Бюллетень сибирской медицины, 2020 The aim of this work was to study the conformational changes of lactate dehydrogenase under the influence of different concentrations of intermediates (pyruvate, oxaloacetate) in the temperature gradient with the subsequent building of a mathematical ...
F. N. Gilmiyarova +7 more
doaj +1 more source
Pakistan Armed Forces Medical Journal, 2021 Objective: To study the diagnostic utility of lactate dehydrogenase levels in differentiating megaloblastic anemia from myelodysplastic anemia in Pakistan. Study Design: Comparative cross-sectional study.
Faraz Ali Rana +5 more
doaj
PLoS ONE, 2015 Female and male adult Wistar rats were fed standard chow or a simplified cafeteria diet for one month. Then, the rats were killed and the white adipose tissue (WAT) in four sites: perigonadal, retroperitoneal, mesenteric and subcutaneous (inguinal) were ...
Sofía Arriarán +5 more
doaj +1 more source