Results 61 to 70 of about 379,267 (388)

Correlation between Persistent Serum Lactate Elevation and Brain Magnetic Resonance Imaging Abnormalities in Children with Status Epilepticus [PDF]

Annals of Child Neurology
Purpose This study was conducted to evaluate the correlation between persistent serum lactate elevation and brain magnetic resonance imaging (MRI) in children with status epilepticus (SE).
Prastiya Indra Gunawan, Riza Noviandi, Sunny Mariana Samosir   +2 more
doaj   +1 more source

“Lactate Shift,” Rather Than “Lactate Clearance,” for Serial Blood Lactate Monitoring?

Critical Care Medicine, 2015
To the Editor:We read with interest the letter to the editor by Dr. Vincent (1) citing our work (2) on blood lactate in patients with sepsis admitted to intensive care, and we broadly agree with the points he raised.
Walker, Craig, Griffith, David, Gray, Alasdair, Datta, Deepankar, Hay, Alastair   +4 more
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Lactation Curves for First Lactation Egyptian Buffalo

Journal of Dairy Science, 1994
First lactation records of 1538 buffalo maintained at the Animal Production Research Institute farms in 1967 to 1990 were used to determine lactation curves for three lactation lengths: > 28 and < 150 d, > 149 d, and > or = 308 d, as well as all records. Daily milk yields were summed by 14-d intervals for analyses.
G H, Metry, K A, Mourad, J C, Wilk, B T, McDaniel   +3 more
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Association of Postoperative Serum Lactate Levels with Acute Kidney Injury in Mexican Patients Undergoing Cardiac Surgery

Clinics and Practice
Acute kidney injury (AKI) is a highly prevalent and a critical complication of cardiac surgery (CS). Serum lactate (sLac) levels have consistently shown an association with morbimortality after CS. We performed a cross-sectional study including 264 adult
Héctor-Enrique Flores-Salinas, Anahí de Jesús Zambada-Gamboa, Texali-Candelaria Garcia-Garduño, Guillermo Rodríguez-Zavala, Yeminia Valle, Juan-Carlos Chávez-Herrera, Porfirio-Eduardo Martinez-Gutierrez, Arturo Godinez-Flores, Salvador Jiménez-Limón, Jorge-Ramón Padilla-Gutiérrez   +9 more
doaj   +1 more source

Comparison of d and l-lactate content in cow and camel milk [PDF]

, 2015
Lactate is the product of fermentation of lactose in the digestive tract of milk consumers. The lactate has benef icial effect on health for the regulation of the milk protein digestion and calcium absorption. However, lactate has two stereoisomere named
Akhmetsadykova, Shynar, Baubekova, Almagul, Faye, Bernard, Kalimbetova, A., Konuspayeva, Gaukhar, Sandugash,   +5 more
core  

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development [PDF]

, 2012
It has been hypothesized that respiration defects caused by accumulation of pathogenic mitochondrial DNA (mtDNA) mutations and the resultant overproduction of reactive oxygen species (ROS) or lactates are responsible for aging and age-associated ...
Hashizume Osamu, Hayashi Jun-Ichi, Itami Makiko, Miyoshi Hiroyuki, Nagase Hiroki, Nakada Kazuto, Ohira Miki, Shimizu Akinori, Sugiyama Atsuko, Takenaga Keizo, Yokota Mutsumi, 中田 和人, 林 純一, 橋爪 脩   +13 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source