Metformin Intoxication, Lactic Acidosis and Death: Case Report
Journal of Basic and Applied Research in Biomedicine, 2022 Metformin is an oral antidiabetic agent used as in the treatment of T2DM. A fearsome complication of the use of metformin is lactic acidosis. A nineteen-year-old woman was unconscious and cyanotic in her home.
Zafer Pekkolay +4 more
doaj
The American Journal of Cardiology, 1963 Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/32231/1/0000292 ...
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A Rare Case of Severe Lactic Acidosis in a Patient With Mantle Cell Lymphoma
Journal of Investigative Medicine High Impact Case Reports, 2021 Lactic acidosis is an extremely rare paraneoplastic manifestation of hematological malignancies, and often carries an extremely poor prognosis. Mantle cell lymphoma is an aggressive and rare form of non-Hodgkin lymphoma.
Kok Hoe Chan MD +5 more
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Assessment of severe malaria in a multicenter, phase III, RTS, S/AS01 malaria candidate vaccine trial: case definition, standardization of data collection and patient care. [PDF]
, 2011 BACKGROUND\ud \ud An effective malaria vaccine, deployed in conjunction with other malaria interventions, is likely to substantially reduce the malaria burden. Efficacy against severe malaria will be a key driver for decisions on implementation.
Amanda Leach +18 more
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Drug-induced metabolic acidosis [PDF]
, 2017 Summary: Drug causes of metabolic acidosis are numerous and their mechanisms are diverse. Broadly, they can cause metabolic acidosis with either a normal anion gap (e.g. drug-induced renal tubular acidosis) or an elevated anion gap (e.g.
Boton +33 more
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Endocrinology, Diabetes & Metabolism Case Reports, 2018 Metformin is recommended as the first-line agent for the treatment of type 2 diabetes. Although this drug has a generally good safety profile, rare but potentially serious adverse effects may occur.
Tess Jacob +2 more
doaj +1 more source
Risk Factors for Symptomatic Hyperlactatemia and Lactic Acidosis Among Combination Antiretroviral Therapy-Treated Adults in Botswana: Results from a Clinical Trial [PDF]
, 2014 Nucleoside analogue reverse transcriptase inhibitors are an integral component of combination antiretroviral treatment regimens. However, their ability to inhibit polymerase-γ has been associated with several mitochondrial toxicities, including ...
Bussmann, Hermann +12 more
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Near infrared spectrometric investigation of lactate in a varying pH buffer [PDF]
, 2020 Lactic acidosis is commonly observed in various disease states in critical care and can be adopted as a hemodynamic biomarker, as well as a target for therapy.
Baishya, N. +5 more
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Severe Metabolic Acidemia in a Patient with Aleukemic Leukemia
Case Reports in Nephrology, 2018 Malignancy associated lactic acidosis is a rare metabolic complication that may accompany various types of malignancies. To date, most cases that have been reported are associated with hematologic malignancies (lymphoma and leukemia).
Moutaz Ghrewati +4 more
doaj +1 more source
Implementing a tenofovir-based first-line regimen in rural Lesotho: clinical outcomes and toxicities after two years. [PDF]
, 2011 The latest World Health Organization guidelines recommend replacing stavudine with tenofovir or zidovudine in first-line antiretroviral therapy in resource-limited settings.
Birkus +12 more
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