Results 61 to 70 of about 2,685,653 (178)

Novel Enzymatic Synthesis of 3-hydroxybutyric Acid Oligomerswith Inserted Lactobionic Acid Moieties [PDF]

, 2011
3-Hydroxybutyric acid and lactobionic acid yielded linear and cyclic oligomers in a lipase-catalyzedcondensation polymerization reaction, performed at 80°C in bulk and organic solvent systems. Novozyme435 was the most efficient biocatalyst, and a mixture
Paul, C., Davidescu, C.M., Kakasi-Zsurka, S., Peter, F., Boeriu, C.G., But, A., Todea, A., Nagv, A.   +7 more
core  

Plastic and adaptive mitochondrial responses help face hypoxia events in a freshwater fish

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Hypoxic events (i.e. reduction of dissolved oxygen in water) are natural events, which intensity and frequency have been amplified by human activities. As oxygen fuels aerobic metabolism, species unable to avoid those events must maintain their functions through ...
Eugénie Dereuder, Tiphaine Menguy, Antoine Stier, Katja Anttila, Amélie Crespel   +4 more
wiley   +1 more source

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Hepatic HIF2α Modulates Extra‐Hepatic Disease‐Associated Phenotypes During Metabolic Dysfunction‐Associated Steatotic Liver Disease

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
High fat, high fructose, high cholesterol “GAN” diet feeding in mice induces MASLD, cardiac dysfunction, loss of lean mass, and hyperinsulinaemia. Hepatocyte‐specific deletion of HIF2α also causes cardiac dysfunction and loss of lean mass but prevents GAN induced hyperinsulinaemia and cardiac sympathetic dominance without preventing MASLD.
Lorenz M. W. Holzner, Rosa M. Korpershoek, Youguo Niu, Anna Cochrane, Paula M. Darwin, Julia Babuta, Areesha Nazeer, Cecilia Castro, Alice P. Sowton, Alice E. Knapton, Benjamin D. Thackray, Julian L. Griffin, Zoe Hall, Dino A. Giussani, Rob C. I. Wüst, Andrew J. Murray   +15 more
wiley   +1 more source

Determination of α-hydroxy acids in cosmetics by UHPLC-MS/MS

Shanghai yufang yixue
ObjectiveTo establish a UHPLC-MS/MS quantitative method for the determination of glucuronic acid， tartaric acid， glycolic acid， malic acid， lactic acid， citric acid， DL-2-hydroxybutyric acid sodium， mandelic acid， benzilic acid， hydroxycaprylic acid ...
RU Ge, XU Yong, HAN Jing, ZHANG Kai, PENG Xingsheng, ZHENG Rong   +5 more
doaj   +1 more source

Consumer Perceptions of Glycation‐Induced Facial Skin Aging and the Role of Skincare Products

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Glycation is a biological process known to exacerbate undesirable skin aging parameters such as yellowing, dullness, wrinkles and reduced elasticity. This study aimed to better understand consumer perceptions of glycation on facial skin and consumer expectations of anti‐glycation skincare. Methods Focus group discussions (FGDs) with
Sharon Shi, Kelly Chua, Bee Leng Lua
wiley   +1 more source

Synthesis of Lactobionic Acid-Grafted-Pegylated-Chitosan with Enhanced Hepg2 Cells Transfection

, 2012
The aim of this study was to develop a functional nanoparticulate carrier with an enhanced transfection in asialoglycoprotein receptor overexpressed HepG2 cells A series of chemical modifications of chitosan were conducted by grafting a hydrophilic ...
林文貞;陳姿丹;張富雄, Lin, Wen Jen; Chen, Tze Dan; Liu, Chia Wen; Chen, Jiin Long; Chang, Fu Hsiung   +1 more
core   +1 more source

Preparation of Betulinic Acid Galactosylated Chitosan Nanoparticles and Their Effect on Liver Fibrosis

International Journal of Nanomedicine, 2022
Zi Chao Wu,1,2,* Xin Yu Liu,1,* Jia Yan Liu,1 Jing Shu Piao,1 Ming Guan Piao1,3 1School of Pharmacy, Yanbian University, Yanji, 133002, People’s Republic of China; 2Research Institute, Shijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang ...
Wu ZC, Liu XY, Liu JY, Piao JS, Piao MG
doaj  

Lactobionic Acid-Navigated Gold Nanorods With Light-Triggered “on-Demand” Drug Release for Synergistic Photothermal-Chemotherapy

Frontiers in Materials, 2022
The rational design of the nanocarriers with active tumor targeting and specific chemotherapy for heat shock protein 90 (Hsp90) inhibition is attractive for combined chemo-photothermal therapy (PTT).
Zhang Zhang, Chunyang Sun
doaj   +1 more source

Magnetic Nanomedicine for Cancer: Mechanisms, Modalities, and Translation

Nano Select, Volume 7, Issue 9, September 2026.
At the convergence of nanotechnology, precision oncology and intelligent therapeutics, magnetic nanoparticles (MNPs) are redefining how cancer is detected, targeted and treated. This review critically examines the mechanisms enabling their integration in imaging, targeted drug delivery and magnetic hyperthermia, while exploring how intelligent design ...
Shivani Kadam, Rahul M. Sonavale, Ratnesh Das, Jayant Pawar, Nutan Shukla, Zhengyou Li, Girish R. Pathade, Nishabh Kushwaha, Asha Patel, Sushilkumar A. Jadhav, Samuel B. Adeloju   +10 more
wiley   +1 more source