Results 51 to 60 of about 2,685,653 (178)
, 2023 Lactobionic acid (LBA) has diverse number of applications in pharmaceutical, food, chemical and nanotechnology fields. Bioproduction of LBA by bi-enzymatic cellobiose dehydrogenase (CDH)/laccase (LAC) is a system where CDH catalyses oxidation of lactose ...
Radivoje Prodanović (15186129) +3 more
core +1 more source
Nanoparticle-Mediated Dual Targeting: An Approach for Enhanced Baicalin Delivery to the Liver
Pharmaceutics, 2020 In this study, water-soluble chitosan lactate (CL) was reacted with lactobionic acid (LA), a disaccharide with remarkable affinity to hepatic asialoglycoprotein (ASGP) receptors, to form dual liver-targeting LA-modified-CL polymer for site-specific drug ...
Iman Saad Ahmed +4 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Cancer cells are under oxidative stress associated with the increased generation of reactive oxygen species (ROS). Therefore, increasing the oxidative stress of tumor cells by delivering ROS generators is an effective strategy to induce apoptosis of ...
Zuoqin Zhou +7 more
doaj +1 more source
Acid Whey Valorization for Biotechnological Lactobionic Acid Bio-production
Journal of Human, Earth, and Future, 2022 The dairy industry is facing a problem associated with 1.6 billion tons of acid whey per year as a waste stream. The extended amount of acid whey has encouraged studies for novel approaches of acid whey utilization. The production of lactobionic acid (LBA) using dairy waste has been in rapid demand as an economically feasible and environmentally ...
Vikram R. Narala +4 more
openaire +2 more sources
Mass Spectrometry Reviews, EarlyView.ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Synthesis of a gadolinium based-macrocyclic MRI contrast agent for effective cancer diagnosis
Biomaterials Research, 2018 Background Gadolinium-based contrast agents are widely used as a contrast agent for magnetic resonance imaging. Since gadolinium ions are toxic, many chelators are developed to bind gadolinium ions to prevent free gadolinium-associated disease.
Yohan Jeong, Kun Na
doaj +1 more source
Redox-Sensitive Nanocomplex for Targeted Delivery of Melittin
Toxins, 2020 Although peptide therapeutics have been explored for decades, the successful delivery of potent peptides in vitro and in vivo remains challenging due to the poor stability, low cell permeability, and off-target effects.
Bei Cheng, Peisheng Xu
doaj +1 more source
Hepatocellular-Targeted mRNA Delivery Using Functionalized Selenium Nanoparticles In Vitro
Pharmaceutics, 2021 Selenium’s (Se) chemopreventative and therapeutic properties have attracted attention in nanomedicine. Se nanoparticles (SeNPs) retain these properties of Se while possessing lower toxicity and higher bioavailability, potentiating their use in gene ...
Dhireshan Singh, Moganavelli Singh
doaj +1 more source
, 2009 A series of chemical modifications of chitosan were conducted by grafting a hydrophilic methoxy poly(ethylene glycol) (MPEG) and a target sugar molecule lactobionic acid( LA).
林文貞;陳姿丹 +4 more
core +1 more source
Smart Molecules, EarlyView.Smart mesoporous silica nanoparticles integrate tunable pore structures, molecular gates, targeting ligands, and stimuli‐responsive components to achieve controlled drug release for precision cancer therapy. This review highlights design principles, therapeutic applications, and future directions in immunotherapy, biodegradability, biosafety, and ...
Majdi Al‐Amili, Lei Lei, Zhu Jin
wiley +1 more source