Results 1 to 10 of about 55,553 (270)

Engineered Lactococcus lactis secreting Flt3L and OX40 ligand for in situ vaccination-based cancer immunotherapy

Nature Communications, 2022
The probiotic Lactococcus lactis has been used for the delivery of therapeutic molecules. Here the authors engineer Lactococcus lactis to express a fusion protein of Flt3L and OX40 ligand, eliciting anti-tumor immune response in preclinical cancer models.
Junmeng Zhu, Yaohua Ke, Qin Liu, Ju Yang, Fangcen Liu, Ruihan Xu, Hang Zhou, Aoxing Chen, Jie Xiao, Fanyan Meng, Lixia Yu, Rutian Li, Jia Wei, Baorui Liu   +13 more
doaj   +2 more sources

Whole-genome sequence analysis and probiotic characteristics of Lactococcus lactis Subsp. lactis strain Lac3 isolated from traditional fermented buffalo milk (Dadih)

Journal of Genetic Engineering and Biotechnology, 2023
Background Probiotics are live microorganisms that provide beneficial effects on the host’s health when exploited in adequate amounts. This study aimed at carrying out whole-genome sequence analysis and in vitro potential probiotic characteristics of ...
Nshimiyimana Sylvere, Apon Zaenal Mustopa, Sri Budiarti, Lita Meilina, Ai Hertati, Ira Handayani   +5 more
doaj   +2 more sources

Physical and Antibacterial Properties of Sodium Alginate—Sodium Carboxymethylcellulose Films Containing Lactococcus lactis

Molecules, 2018
Edible films have gradually become a research focus for food packaging materials due to a variety of benefits, including environmental friendliness, good barrier properties, and good carrying capacity.
Jingsong Ye, Donghui Ma, Wen Qin, Yaowen Liu   +3 more
doaj   +2 more sources

From Genome to Phenotype: An Integrative Approach to Evaluate the Biodiversity of Lactococcus lactis

Microorganisms, 2017
Lactococcus lactis is one of the most extensively used lactic acid bacteria for the manufacture of dairy products. Exploring the biodiversity of L. lactis is extremely promising both to acquire new knowledge and for food and health-driven applications. L.
Valérie Laroute, Hélène Tormo, Christel Couderc, Muriel Mercier-Bonin, Pascal Le Bourgeois, Muriel Cocaign-Bousquet, Marie-Line Daveran-Mingot   +6 more
doaj   +2 more sources

Metabiotics - development of probiotic concept [PDF]

Технологія виробництва і переробки продуктів тваринництва, 2022
The urgency of development of technology of synbiotic dairy products with metabolites on the basis of microbial consortia of probiotic bacteria is substantiated in the article.
Kryzhak L., Kalinina H.
doaj   +1 more source

Effect of Lactobacteria on Bioactive Peptides and Their Sequence Identification in Mature Cheese

Microorganisms, 2022
An in silico study that featured the effect of starter cultures on the bioactivity and other health benefits of peptides in semi-hard cheese is presented in this contribution.
Marina Kurbanova, Roman Voroshilin, Oksana Kozlova, Victor Atuchin   +3 more
doaj   +1 more source

Microbiota composition and intestinal barrier function modulated by tamsulosin and <i>Lactococcus lactis</i> in a cirrhosis rat model. [PDF]

Front Cell Infect Microbiol
Padilla-García SV, Loera-Muro A, Muñoz-Ortega MH, Hernández-Marín DA, Ventura-Juárez J, Martínez-Hernández SL.   +5 more
europepmc   +3 more sources

Immunoregulatory effects of Lactococcus lactis‐derived extracellular vesicles in allergic asthma

Clinical and Translational Allergy, 2022
Background Probiotics have been shown to prevent various allergic diseases by producing extracellular vesicles (EVs). However, the role of EVs in allergic asthma has not yet been completely determined.
Dong-Hyun Lee, H. Park, Hee-Ra Lee, Hyeukjun Sohn, Soyoon Sim, H. Park, Y. Shin, Yoon-Keun Kim, Youngwoo Choi, Hae‐Sim Park   +9 more
semanticscholar   +1 more source

Health-Promoting Nature of Lactococcus lactis IBB109 and Lactococcus lactis IBB417 Strains Exhibiting Proliferation Inhibition and Stimulation of Interleukin-18 Expression in Colorectal Cancer Cells

Frontiers in Microbiology, 2022
Lactic acid bacteria (LAB) are Gram-positive bacteria which are considered for use as adjuvant therapeutics in management of various disease ailments, including obesity, irritable bowel syndrome, lactose intolerance and cancer.
Przemysław Sałański, M. Kowalczyk, J. Bardowski, A. Szczepankowska   +3 more
semanticscholar   +1 more source

Live Biotherapeutic Lactococcus lactis GEN3013 Enhances Antitumor Efficacy of Cancer Treatment via Modulation of Cancer Progression and Immune System

Cancers, 2022
Simple Summary Recent studies, which have revealed the strong relationship between gut microbiota and tumor progression, have driven the clinical application of microbiome-based treatments to increase the efficacy of anticancer therapies.
Sujeong Kim, Yunjae Kim, Suro Lee, Y. Kim, B. Jeon, Hyerim Kim, H. Park   +6 more
semanticscholar   +1 more source