Leishmanicidal Activity of Aliphatic and Aromatic Lactones: Correlation Structure-Activity
Several aliphatic and aromatic lactones and two dimers were synthesized using the sequence: allylation - esterification - metathesis. These compounds were active in vitro against intracellular amastigotes of Leishmania panamensis.
Fernando Echeverri +4 more
doaj +1 more source
Modulation of Cox-1, 5-, 12- and 15-Lox by popular herbal remedies used in southern Italy against psoriasis and other skin diseases. [PDF]
Acanthus mollis (Acanthaceae), Achillea ligustica, Artemisia arborescens and Inula viscosa (Asteraceae) are used in Southern Italy against psoriasis and other skin diseases that occur with an imbalanced production of eicosanoids.
Amenta +26 more
core +1 more source
Sesquiterpene lactones (STLs) are a prominent group of plant secondary metabolites predominantly found in the Asteraceae family and have multiple ecological roles and medicinal applications. This review describes the evolutionary and ecological significance of STLs, highlighting their roles in plant defence mechanisms against herbivory and as ...
Olivia Agatha +3 more
openaire +4 more sources
Sulfur‐Directed Construction of Vinyl Cyclopropanes from 1,3‐Dienes
Sulfur takes control. A pending thioether acts as a molecular compass, directing carbene addition to the 1,3‐diene scaffold with exceptional regio‑ and diastereocontrol to forge sulfur‐substituted vinyl cyclopropanes (S‐VCPs) — molecular architectures inaccessible via conventional cyclopropanation strategies.
Anna Keimer +6 more
wiley +1 more source
Bicyclic chloro-, bromo- and iodo-γ-lactones with dimethylcyclohexane rings were used as substrates for bioconversion by several fungal strains (<em>Fusarium</em>, <em>Botrytis</em> and <em>Beauveria</em>). Most of the
Małgorzata Grabarczyk
doaj +1 more source
Identification of a novel ß-adrenergic octopamine receptor-like gene (ßAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks [PDF]
Background: The cattle tick Rhipicephalus (Boophilus) microplus is an economically important parasite of livestock. Effective control of ticks using acaricides is threatened by the emergence of resistance to many existing compounds. Several continuous R.
Bell-Sakyi, Lesley +4 more
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Synthesis of (+)-Marmelo Lacton A and (+)-Marmelo Lactone B [PDF]
NISHIDA, Yoshihiro +2 more
openaire +2 more sources
Cycloaddition Reactions of C,N-Diphenylnitrone to Methylene-γ-butyrolactones
Cycloaddition of C,N-diphenylnitrone to α-methylene-γ-butyrolactone afforded two diastereomeric 5-spirosubstituted isoxazolidines with high selectivity.
Andrea Goti +3 more
doaj +1 more source
ABSTRACT Saturated fatty acids (SFAs) are generally regarded simply as being resistant to oxidation compared with unsaturated fatty acids. However, it has long been reported that SFAs can undergo oxidation when heated at high temperatures, leading to the formation of unique degradation products such as 2‐alkanones and lactones.
Kanji Aoyagi +2 more
wiley +1 more source

