Results 91 to 100 of about 7,301 (235)
Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.Key Lentinula edodes (Shiitake) metabolites and their therapeutic roles. Lentinic acid, shiitakeols A/B, and lanostanoids show anti‐inflammatory activity; lentinan and latcripin derivatives possess anticancer effects; sterols, β‐glucans, and eritadenine are hepatoprotective.
Bikash Baral
wiley +1 more source
Abnormalities of glycosphingolipid, sulfatide, and ceramide in the polycystic (cpk/cpk) mouse.
Journal of Lipid Research, 1994 Polycystic kidney disease is a disorder marked by aberrant renal tubular epithelial cell proliferation and transport abnormalities. Sphingolipids are ubiquitous membrane components implicated in several cellular functions including cell membrane sorting,
G D Deshmukh +3 more
doaj +1 more source
alpha -Lactalbumin (LA) Stimulates Milk beta-1,4-Galactosyltransferase I (beta 4Gal-T1) to Transfer Glucose from UDP-glucose to N-Acetylglucosamine: CRYSTAL STRUCTURE OF beta 4Gal-T1·LA COMPLEX WITH UDP-Glc* [PDF]
, 2001 beta-1,4-Galactosyltransferase 1 (Gal-T1) transfers galactose (Gal) from UDP-Gal to N-acetylglucosamine (GlcNAc), which constitutes its normal galactosyltransferase (Gal-T) activity.
Qasba, Pradman K. +2 more
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Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]
, 2018 Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn +2 more
core +1 more source
Proteomic analysis of lactosylceramide-enriched membrane microdomains
Trends in Glycoscience and Glycotechnology, 2008 生体膜マイクロドメイン（リピドラフト）はコレステロールとスフィンゴ糖脂質に富む膜上の微小領域で，細胞の内外をつなぐさまざまな細胞反応に関与している。我々はラクトシルセラミドの集積する細胞膜マイクロドメインに焦点を当て，好中球の機能を研究している。好中球の生体膜マイクロドメインは貪食などの機能に関与することが知られているが，その分子メカニズムはまだ十分には明らかにされていない。この総説では生体膜マイクロドメインが機能する際の分子メカニズムを明らかにするために，その構成タンパク質を網羅的に調べる戦略について概説する。
Mitsuaki Yanagida, Kazuhisa Iwabuchi
openaire +2 more sources
Lactosylceramide-enriched glycosphingolipid signaling domain mediates superoxide generation from human neutrophils [PDF]
Blood, 2002 This study is focused on the functional significance of neutrophil lactosylceramide (LacCer)–enriched microdomains, which are involved in the initiation of a signal transduction pathway leading to superoxide generation. Treatment of neutrophils with anti-LacCer antibody, T5A7 or Huly-m13, induced superoxide generation from the cells, which was blocked ...
Kazuhisa, Iwabuchi, Isao, Nagaoka
openaire +2 more sources
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
Glia, Volume 73, Issue 12, Page 2338-2352, December 2025.Main Points Sensory neurons depend on Schwann cells for survival. Schwann cells provide energy for axons dunng rapid firing or after injury. Dysregulated metabolism in Schwann cells can lead to the production of neurotoxic and axon degeneration. ABSTRACT Schwann cells are the glial cells in the peripheral nervous system responsible for the production ...
Rose Follis +2 more
wiley +1 more source
Journal of Lipid Research, 1988 CMP-N-acetylneuraminate:lactosylceramide alpha-2,3-sialyltransferase is tightly associated with the luminal side of the Golgi membrane as is its lipid substrate, lactosylceramide.
H Kadowaki, L A Symanski, R S Koff
doaj +1 more source
Metabolomics study of fibroblasts damaged by UVB and BaP
Scientific Reports, 2021 We have recently shown that both UVB and BaP can induce the production of ROS, apoptosis and even cancer. However, the differences in the metabolic profiles of skin damaged by UVB, BaP or UVB combined with BaP have not been studied.
Xiaoyu Yang +5 more
doaj +1 more source
P-selectin mediates metastatic progression through binding to sulfatides on tumor cells [PDF]
, 2017 Hematogenous carcinoma metastasis is associated with tumor cell emboli formation, which is now known to be facilitated by selectins. P-selectin-mediated interactions of platelets with cancer cells are based mostly on mucin- and glycosaminoglycan-type ...
Borsig, L., Callewaert, N., Garcia, J.
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