Results 41 to 50 of about 3,664 (121)

Lambert-Eaton Myasthenic Syndrome Caused by Nivolumab in a Patient with Squamous Cell Lung Cancer

Case Reports in Neurology, 2018
Lambert-Eaton myasthenic syndrome (LEMS) is a representative paraneoplastic neurological syndrome. Recently, nivolumab, an anti-programmed cell death 1 inhibitor, has been approved for advanced non-small-cell lung cancer. Careful attention should be paid
Yuki Nakatani, Natsuki Tanaka, Tomomi Enami, Seigo Minami, Tomoko Okazaki, Kiyoshi Komuta   +5 more
doaj   +1 more source

Paraneoplastic neurological syndromes

Orphanet Journal of Rare Diseases, 2007
Paraneoplastic neurological syndromes (PNS) can be defined as remote effects of cancer that are not caused by the tumor and its metastasis, or by infection, ischemia or metabolic disruptions.
Antoine Jean-Christophe, Honnorat Jérôme   +1 more
doaj   +1 more source

Relapse of both small cell lung cancer and Lambert–Eaton myasthenic syndrome after a 13-year disease-free survival period

Chinese Journal of Cancer, 2016
Lambert–Eaton myasthenic syndrome (LEMS) is a paraneoplastic syndrome and only 3% of small cell lung carcinoma (SCLC) patients have LEMS. Moreover, the recurrence of SCLC after a disease-free survival (DFS) of more than 10 years is rare.
Fumio Asano, Keisuke Watanabe, Masaharu Shinkai, Yoshitaka Tei, Kei Mishina, Mikiko Tanabe, Hiroshi Ishii, Masahiro Shinoda, Tadasuke Shimokawaji, Makoto Kudo, Takeshi Kaneko   +10 more
doaj   +1 more source

Electrophysiological and muscle pathological characteristics of Lambert - Eaton myasthenic syndrome

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To summarize the electrophysiological and muscle pathological characteristics of Lambert - Eaton myasthenic syndrome (LEMS). Methods and Results Twelve LEMS patients referred to China - Japan Friendship Hospital between January 2010 and ...
SUN Qing, JIAO Jin-song, SUN Shao-jie, WANG Wei, PENG Dan-tao, WANG Ren-bin   +5 more
doaj   +1 more source

Autoantibodies in neuromuscular disorders: a review of their utility in clinical practice

Frontiers in Neurology
A great proportion of neuromuscular diseases are immune-mediated, included myasthenia gravis, Lambert-Eaton myasthenic syndrome, acute- and chronic-onset autoimmune neuropathies (anti-MAG neuropathy, multifocal motor neuropathy, Guillain-Barré syndromes,
Valentin Loser, Alex Vicino, Marie Théaudin   +2 more
doaj   +1 more source

Non-paraneoplastic Lambert-Eaton myasthenic syndrome: a brief review of 10 cases

Arquivos de Neuro-Psiquiatria, 2010
Lambert-Eaton myasthenic syndrome (LEMS) is an immune-mediated disorder of the presynaptic neuromuscular transmission, which more frequently occurs as the remote effect of a neoplasm, in the paraneoplastic form (P-LEMS), or in a non-paraneoplastic form ...
Paulo J. Lorenzoni, Rosana H. Scola, Cláudia S. Kamoi Kay, Sérgio F. Parolin, Lineu C. Werneck   +4 more
doaj   +1 more source

Immunoglobulins to mitigate paraneoplastic Lambert Eaton Myasthenic Syndrome under checkpoint inhibition in Merkel cell carcinoma

Neurological Research and Practice, 2020
Lambert-Eaton myasthenic syndrome (LEMS) is a rare, autoimmune or paraneoplastic condition characterized by muscle weakness and fatigability. In cancer therapy, immune checkpoint inhibitors (ICI) sensitize the immune system for tumor antigens.
Maike F. Dohrn, Ulrike Schöne, Charlotte Küppers, Deborah Christen, Jörg B. Schulz, Burkhard Gess, Simone Tauber   +6 more
doaj   +1 more source

Clinical features of neuromuscular disorders in patients with N-type voltage-gated calcium channel antibodies

European Journal of Translational Myology, 2016
Neuromuscular junction disorders affect the pre- or postsynaptic nerve to muscle transmission due to autoimmune antibodies. Members of the group like myasthenia gravis and Lambert-Eaton syndrome have pathophysiologically distinct characteristics. However,
Andreas Totzeck, Petra Mummel, Oliver Kastrup, Tim Hagenacker   +3 more
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The association between Lambert–Eaton myasthenic syndrome and small cell lung carcinoma

ImmunoTargets and Therapy, 2013
Sarah EW Briggs,1 Paul Gozzard,2 Denis C Talbot31Department of Oncology, Oxford University Hospitals Trust, Churchill Hospital, Oxford, UK; 2Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford UK ...
Briggs SEW, Gozzard P, Talbot DC
doaj  

Electrophysiological study in neuromuscular junction disorders

Annals of Indian Academy of Neurology, 2013
This review is on ultrastructure and subcellular physiology at normal and abnormal neuromuscular junctions. The clinical and electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS), congenital myasthenic syndromes ...
Ajith Cherian, Neeraj N Baheti, Thomas Iype   +2 more
doaj   +1 more source