Síndromes paraneoplásicas neurológicas.
Acta Médica Portuguesa, 1995 Some neurologic syndromes are often associated with neoplasm, as a paraneoplastic disorder. Among them, namely, subacute cerebellar degeneration, sensory neuronopathy, dermatomyositis/polymyositis, Lambert-Eaton myasthenic syndrome and subacute motor ...
A N Morganho +3 more
doaj +1 more source
Facilitatory actions of guanidine on synaptic transmission in mammalian brain slices [PDF]
, 1979 Guanidine administration may be beneficial in the treatment of amyotrophic lateral sclerosis and related diseases; however, the actions of guanidine on the mammalian central nervous system have not been investigated.
Galvan, Martin +2 more
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Ion channels: structural basis for function and disease. [PDF]
, 1996 Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
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Partial Response in an RRx-001-Primed Patient with Refractory Small-Cell Lung Cancer after a Third Introduction of Platinum Doublets. [PDF]
, 2016 Small-cell lung cancer (SCLC), initially exquisitely sensitive to first-line cisplatin/etoposide, invariably relapses and acquires a multidrug chemoresistant phenotype that generally renders retreatment with first-line therapy both futile and ...
Brzezniak, Christina +7 more
core +3 more sources
The Relationship Between Immune Semaphorins and Myasthenia Gravis
Brain and Behavior, Volume 16, Issue 3, March 2026.Serum alterations of immune‐related semaphorins in myasthenia gravis. Patients exhibited decreased semaphorin 4A and increased semaphorin 7A levels compared with healthy controls. These changes highlight disturbed immune regulation in myasthenia gravis and support the involvement of semaphorin‐mediated pathways in autoimmune neuromuscular junction ...
Dilcan Kotan +2 more
wiley +1 more source
Paraneoplastic Motor Neuropathy in Nodular Sclerosis Hodgkin’s Lymphoma: Case Report
Case Reports in Hematology, Volume 2026, Issue 1, 2026.Paraneoplastic neurological syndromes (PNS) are an uncommon complication of malignancy, characterized by autoantibody generation against neuronal structures, causing a spectrum of neurological syndromes affecting the central, peripheral, and/or autonomic nervous systems. PNS in lymphoma is exceedingly rare and there is limited evidence on the features,
Jayesh Menon +4 more
wiley +1 more source
The Active and Periactive Zone Organization and the Functional Properties of Small and Large Synapses [PDF]
, 2016 The arrival of an action potential (AP) at a synaptic terminal elicits highly synchronized quanta release. Repetitive APs produce successive synaptic vesicle (SV) fusions that require management of spent synaptic vesicle components in the presynaptic ...
Lucia Tabares, Raquel Cano
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A Case of Voltage‐Gated Calcium Channel and TG6 Antibody–Positive Cerebellar Ataxia
Case Reports in Neurological Medicine, Volume 2026, Issue 1, 2026.We present the case of a lady in her early 20s who developed over a few weeks progressive appendicular and limb ataxia and dysarthria. She was found to have a high titer of voltage‐gated calcium channel antibodies (VGCCAs) and was started on immunosuppressive and immunomodulating therapy with no further worsening of her neurological status.
Alberto Cifelli +4 more
wiley +1 more source
MGBase: A Global, Observational Registry for Collaborative Research in Myasthenia Gravis
Muscle &Nerve, Volume 72, Issue 3, Page 424-432, September 2025.ABSTRACT Introduction/Aims Patient registries are valuable tools for outcomes research in rare diseases such as myasthenia gravis (MG). Existing MG registries are limited by factors including a lack of geographical scope. MGBase has been designed as a global, observational registry aimed at studying clinical practice outcomes in MG.
Katherine A. Buzzard +28 more
wiley +1 more source
‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII [PDF]
, 2015 Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis.
Jarius, Sven, Wildemann, Brigitte
core +3 more sources