Síndrome de Lambert-Eaton paraneoplásico en carcinoma de células pequeñas de pulmón [PDF]
Lambert Eaton myasthenic syndrome is a paraneoplastic autoimmune pathology mostly associated with lung cancer, which manifests itself with involvement of the neuromuscular junction and autonomic dysfunctions.
Barrantes Astorga, Gerald Josué +2 more
core +2 more sources
Anti-glial nuclear antibody (AGNA) is an onconeuroal antibody targeting the nuclei of Bergmann glia in the cerebellum and Anti-SRY-related HMG-box 1 (SOX1).
Jonas Feldheim +4 more
doaj +1 more source
Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner +19 more
core +1 more source
Episodic neurologic disorders: syndromes, genes, and mechanisms. [PDF]
Many neurologic diseases cause discrete episodic impairment in contrast with progressive deterioration. The symptoms of these episodic disorders exhibit striking variety.
Fu, Ying-Hui +2 more
core +2 more sources
Lambert-Eaton Syndrome in Children
Investigators from Boston Children's Hospital; the Lahey Clinic, Burlington, MA; and Ohio State University, report 3 children presenting between ages 9 and 10 years with proximal lower extremity weakness with areflexia and low-amplitude compound muscle ...
J Gordon Millichap, John J Millichap
doaj +1 more source
Clinical applications of immunoglobulin in neuromuscular diseases: focus on inflammatory myopathies [PDF]
During recent years, an increasing number of neuromuscular diseases have been recognized either to be caused primarily by autoimmune mechanisms, or to have important autoimmune components.
Oliveira, Acary Souza Bulle +2 more
core +3 more sources
Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation. [PDF]
BackgroundCongenital myasthenic syndromes (CMSs) are a group of inherited disorders of neuromuscular transmission that may be presynaptic, synaptic, or postsynaptic.
Anderson, Kendall J +11 more
core
Lowering the cutoff value for increment increases the sensitivity for the diagnosis of Lambert-Eaton myasthenic syndrome [PDF]
Background: Increment of compound muscle action potential amplitude is a diagnostic hallmark of Lambert-Eaton myasthenic syndrome (LEMS). Making a diagnosis can be challenging, therefore, a proper cutoff for abnormal increment is highly relevant for ...
Lipka, A.F. (Alexander F.) +3 more
core +4 more sources
Stimulated single-fiber electromyography (sSFEMG) in Lambert-Eaton syndrome
Objective: To report the clinical features and the neurophysiological approach of a patient with Lambert-Eaton myasthenic syndrome (LEMS), highlighting the diagnostic role of the stimulated single fiber electromyography (sSFEMG).
Vincenzo Todisco +5 more
doaj +1 more source
‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 2: Anti-PKC-gamma, anti-GluR-delta2, anti-Ca/ARHGAP26 and anti-VGCC [PDF]
Serological testing for anti-neural autoantibodies is important in patients presenting with idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict prognosis.
Jarius, Sven, Wildemann, Brigitte
core +1 more source

