Results 71 to 80 of about 6,688 (239)

Long-term follow-up, quality of life, and survival of patients with Lambert-Eaton myasthenic syndrome [PDF]

, 2020
ObjectiveTo study survival and to characterize long-term functional impairments and health-related quality of life (HRQOL) of patients with Lambert-Eaton myasthenic syndrome (LEMS).MethodsIn this observational study, survival of patients with LEMS ...
Boldingh, Marion I., Kuks, Jan B. M., Lipka, Alexander F., Schreurs, Marco W. J., Tallaksen, Chantal M., Titulaer, Maarten J., van Zwet, Erik W., Verschuuren, Jan J. G. M.   +7 more
core   +2 more sources

Efficacy and Safety of Efgartigimod for Patients With Myasthenia Gravis in a Real‐World Cohort of 77 Patients

CNS Neuroscience &Therapeutics, Volume 31, Issue 4, April 2025.
This real‐world study of 77 myasthenia gravis (MG) patients treated with efgartigimod showed rapid symptom improvement across disease severities. Sustained efficacy was achieved with repeated cycles, positioning efgartigimod as a promising MG therapy combining swift response and durable maintenance benefits. ABSTRACT Aims Efgartigimod, a first‐in‐class
Sijia Hao, Zhe Ruan, Rongjing Guo, Qingqing Wang, Xiaoxi Huang, Chao Sun, Huanhuan Li, Ting Gao, Yonglan Tang, Xiangqi Cao, Yu Liu, Zhuyi Li, Ting Chang   +12 more
wiley   +1 more source

Update on treatment options for Lambert–Eaton myasthenic syndrome: focus on use of amifampridine

Neuropsychiatric Disease and Treatment, 2011
Sabine Lindquist, Martin StangelSection Clinical Neuroimmunology and Neurochemistry, Department of Neurology, Hannover Medical School, Hannover, GermanyAbstract: In Lambert–Eaton myasthenic syndrome (LEMS), antibodies against presynaptic ...
Lindquist S, Stangel M
doaj  

Gender issues of antibody-mediated diseases in neurology: (NMOSD/autoimmune encephalitis/MG)

Therapeutic Advances in Neurological Disorders, 2020
Neuromyelitis optica spectrum disorder (NMOSD), autoimmune encephalitis (AE), myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are antibody-mediated neurological diseases.
Ayse Altintas, Justina Dargvainiene, Christiane Schneider-Gold, Nasrin Asgari, Ilya Ayzenberg, Andrea I. Ciplea, Ralf Junker, Frank Leypoldt, Klaus-Peter Wandinger, Kerstin Hellwig   +9 more
doaj   +1 more source

A 47-Year Old Female with Muscular Rigidity, New-Onset Diabetes and Hypothyroidism [PDF]

, 2013
Background This case highlights a rare but devastating neurologic condition, Stiff Person Syndrome (SPS). While symptoms of muscular rigidity andspasms areassocia ted with numerous neuromuscular conditions, the association between SPS, autoimmune ...
Valentino, MD, PhD, Michael A.
core   +2 more sources

Clinical Features of Glutamic Acid Decarboxylase‐65 Neurological Autoimmunity: A Case Series From China

CNS Neuroscience &Therapeutics, Volume 31, Issue 2, February 2025.
The clinical spectrum of GAD65 autoimmune neurological diseases appeared highly diverse. Immunotherapy can benefit the majority of patients, and early treatment appeared to be associated with good prognosis. RTX may be more effective than MMF; however, this requires more rigorous prospective studies to explore.
Zhandong Qiu, Fang Xu, Mengyao Zhang, Xixi Yang, Yan Han, Dawei Li, Liang Liu, Jia Chen, Lehong Gao, Qing Xue, Yue Hou, Ying Sun, Li Di, Chunqiu Fan, Junhua Liang, Yue Han, Huiqing Dong, Junwei Hao, Zheng Liu   +18 more
wiley   +1 more source

Adenocarcinoma of Lung Presenting as Lambert-Eaton Myasthenic Syndrome

Journal of Investigative Medicine High Impact Case Reports, 2017
Lambert-Eaton myasthenic syndrome (LEMS) is a paraneoplastic neuromuscular junction disorder. LEMS presents with muscular weakness and fatigability, mainly involving the proximal lower limbs.
Sumera Bukhari MD, Rabia Soomro MD, Shaikh Fawwad MD, Chikezie Alvarez MD, Sara Wallach MD   +4 more
doaj   +1 more source

Myasthenia gravis and Lambert-Eaton myasthenic syndrome: treatment options and guidance for management during COVID-19 pandemic

Neurologijos seminarai, 2020
Myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are immune-mediated neurologic disorders characterized by muscle weakness and fatigue. MG is the most common neuromuscular junction disorder while LEMS is an extraordinary rare disease.
A. Klimašauskienė , R. Bunevičiūtė
doaj   +1 more source

Intramuscular Pressure of Tibialis Anterior Reflects Ankle Torque but Does Not Follow Joint Angle-Torque Relationship [PDF]

, 2018
Intramuscular pressure (IMP) is the hydrostatic fluid pressure that is directly related to muscle force production. Electromechanical delay (EMD) provides a link between mechanical and electrophysiological quantities and IMP has potential to detect local
Aquilonius, Aratow, Ates, Ateş, Ateş, Baumann, Blackburn, Cavanagh, Chiou-Tan, Crenshaw, Davis, De Luca, Di Fabio, Dick, Erdemir, Garfin, Gershuni, Go, Granata, Holtermann, Hopkins, Hug, Hug, Jensen, Karakuzu, Kaufman, Kendall, Klein, Komi, Lacourpaille, Lawrence, Le Mansec, Libardi, Maganaris, Maganaris, Marsh, Merletti, Nordez, Nordez, Norman, Pasquet, Perry, Reinhardt, Röhrle, Sejersted, Sejersted, Solomonow, Solomonow, Tsintzas, van Schaik, Wickiewicz, Yammine   +51 more
core   +2 more sources

Nanoflowers Templated CuO/Cu Hybrid Metasurface for Sensitive THz‐TDS Detection of Acetylcholine

Advanced Sensor Research, Volume 3, Issue 12, December 2024.
This research focuses on sensitively detecting acetylcholine in the terahertz range through the integration of CuO nanoflowers with Cu nanoslots. The terahertz transmittance measurements are recalibrated by incorporating acidic components hydrolyzed from acetylcholine.
Soo Hyun Lee, Taeyeon Kim, Minah Seo
wiley   +1 more source