Results 191 to 200 of about 52,713 (325)
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés+19 more
wiley +1 more source
Lamin A/C promotes HBV transcription by modulating histone modification associated with cccDNA minichromosome in an HBx-dependent manner. [PDF]
Jiang L+9 more
europepmc +1 more source
Arrhythmogenic Cardiomyopathy: Towards Genotype Based Diagnoses and Management
To improve arrhythmogenic cardiomyopathy (ACM) patient care four pillars of ACM research are necessary. The first pillar to improve ACM is cohort studies in which the genotype‐specific natural history of disease is described, and subsequently genotype‐specific risk calculators can be developed, such as the DSP and PLN risk calculators.
Steven A. Muller+13 more
wiley +1 more source
SMCHD1 maintains heterochromatin, genome compartments and epigenome landscape in human myoblasts. [PDF]
Huang Z+6 more
europepmc +1 more source
DNase I hypersensitive sites and transcriptional activation of the lamin A/C gene [PDF]
Kazuhiko Nakamachi, Noboru Nakajima
openalex +1 more source
ABSTRACT Background Bipolar radiofrequency ablation has been increasingly used in cases with deep intramyocardial circuits refractory to unipolar ablation. Patients with Lamin A/C cardiomyopathy frequently exhibit VT arrhythmia originating from deep in the interventricular septum. Methods and Results We describe our use of bipolar ablation in a patient
Alaa A. Shalaby+9 more
wiley +1 more source
The interaction between lamin A and the cytoplasmic skeleton plays a key role in maintaining nuclear mechanical properties. However, the effect of destruction of the cytoplasmic skeleton on the 3D submicroscopic structure of lamin A has not been ...
Zhenyu Yang+6 more
doaj
Store-operated calcium entry facilitates LPS-induced superoxide anion-dependent macrophage extracellular traps. [PDF]
Nguyen TN+7 more
europepmc +1 more source