Results 181 to 190 of about 54,589 (273)

Nuclear Wrinkles Result From Geometric Adaptations to Cellular and Nuclear Morphological Changes in Epithelial Cells

Genes to Cells, Volume 31, Issue 6, November 2026.
Changes in cell geometry caused by increased cell density, F‐actin disruption, or trypsinization promote nuclear rounding and nuclear wrinkle (NW) formation. NWs arise through passive redistribution of excess nuclear surface area and are reversible, without detectable DNA damage, stress‐associated histone H3 Ser10 phosphorylation, or global nuclear ...
Le Minh Khoa, Yohei Kono, Takeshi Shimi, Hiroshi Kimura   +3 more
wiley   +1 more source

Progerin cross-linking stiffens the nucleus and impairs mechanosensation in Hutchinson-Gilford progeria syndrome. [PDF]

J Cell Sci
Srivastava LK, Ghagre A, Duchastel-Vassaramva I, Ehrlicher AJ.   +3 more
europepmc   +1 more source

The Role of Actin‐Filament Bundling Protein, Fimbrin Sac6, and Type‐V Myosin Myo2, in the Motion of the SUN‐Domain Protein, Mps3, During Yeast Meiosis

Genes to Cells, Volume 31, Issue 6, November 2026.
Type‐V myosin (Myo2) promotes the motion of Mps3 patches on the nuclear membrane during yeast meiosis. On the other hand, Sac6 fimbrin, which bundles actin filaments, is not critical for the motion of Mps3, suggesting the role of a few actin filaments in the Mps3 motion.
Shuangping Cheng, Tadasu Nozaki, Yurika Fujita, Masaru Ito, Akira Shinohara   +4 more
wiley   +1 more source

The Lamin Proteins in Nuclear Structure, Functions, and Laminopathies. [PDF]

Cells
Zhao G, Chen Z, Yang C, Liu M, Wang W, Zhang C.   +5 more
europepmc   +1 more source

Hepatic Steatosis in People With Chronic Hepatitis B in Africa: Prevalence, Correlates, and Clinical Significance

Journal of Viral Hepatitis, Volume 33, Issue 11, November 2026.
ABSTRACT To address data gaps around metabolic liver disease in Africa, within the Hepatitis B in Africa Collaborative Network (HEPSANET), we evaluated participants with chronic hepatitis B virus infection (CHB) for steatotic liver disease (SLD) using transient elastography with controlled attenuation parameter (CAP).
Freeman W. Chabala, Edford Sinkala, Alana T. Brennan, Amy Miskimon Goss, Lamin Bojang, Yusupha Samateh, Alexander J. Stockdale, Roger Sombie, Arouna Sessouma, Alice Nanelin Guingane, Juste Aristide Goungounga, Mohamed El‐Kassas, Eman Marwan, Ibrahima Diallo, Abdoul Sow, Edith Okeke, Attah Okwute, Hans Prozesky, Zahiera Ismail, Mark Sonderup, C. Wendy Spearman, Philippa C. Matthews, Judicaël Malick Tine, Maud Lemoine, Hailemichael Desalegn Mekonnen, Asgeir Johnannessen, Michael J. Vinikoor, on behalf of Hepatitis B in Africa Collaborative Network (HEPSANET), Alice Guingane, Roger Sombie, Asgeir Johannessen, Edith Okeke, Mohamed El‐Kassas, Gilles Wandeler, Ibrahima Diallo, Joan Rugemalila, Wendy Spearman, Hans Prozesky, Alex Stockdale, Maud Lemoine, Babatunde Duduyemi, Mary Afihene, Edford Sinkala, Asgeir Johannessen, Roger Sombie, Alex Stockdale, Alice Guingane, Michael Vinikoor, Edith Okeke, Maud Lemoine, Philippa Matthews, Wendy Spearman, Adria Ramirez   +52 more
wiley   +1 more source

An Unbiased Drug Screen in a Drosophila Model of <i>LMNA</i>-Muscular Dystrophy Identifies Calcium Channel Blockers as Potential Treatments. [PDF]

Int J Mol Sci
Mohar NP, Powers BA, Hinz BE, Bock AR, McCoy-Munger H, Darr Z, Shumaker MW, Wemmie AT, Saxena A, Wallrath LL.   +9 more
europepmc   +1 more source

Coordination of drought‐adaptive root growth plasticity through auxin homeostasis by the ZmSPL12–ZmYUC5 module in maize

New Phytologist, Volume 252, Issue 4, Page 1526-1544, November 2026.
Proposed model of ZmSPL12‐mediated drought resistance through auxin regulation. Summary Climate change‐induced drought increasingly threatens global maize production. Drought‐adaptive root plasticity in maize depends on auxin signaling, yet how auxin homeostasis is dynamically tuned in response to water deficit remains unclear.
Hua Xu, Lei Ma, Qingyun Zhang, Zhigang Zheng, Jiajing Li, Sen Yang, Yanfeng Zhao, Lian Jin, Binbin Zhao, Zhijing Bai, Jiyuan Cao, Youpeng Tao, Junjie Zou, Baobao Wang, Shujing Cheng, Jinfang Chu, Jiafan Liu, Haiyang Wang, Miaoyun Xu   +18 more
wiley   +1 more source

Emerging roles of α/β hydrolase domain (ABHD) proteins in S-palmitoylation modification: molecular mechanisms, structural features, and pathological implications. [PDF]

Cell Mol Biol Lett
Wen X, Liu M, Quan Y, Xu Y, Xu J, Shi X.
europepmc   +1 more source

AKT Phosphorylation of FOXK2 at Ser398 Impacts Breast Cancer Cell Growth and Viability

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Higher FOXK2 protein levels are associated with increased AKT phosphorylation and chemoresistance in breast cancer cells. AKT modulates FOXK2 protein levels, with no such regulation in FOXK2 mRNA levels. GSK3β, a known substrate of AKT (dotted arrow), does not regulate FOXK2 in our cellular model.
L. T. Carneiro, J. M. R. C. Nunes, G. De Gregoriis, B. S. Mendonça, W. M. Araújo, R. C. Maia, E. W. F. Lam, R. S. Carvalho, M. A. Carvalho, A. D. Sharrocks, G. Nestal de Moraes   +10 more
wiley   +1 more source

Telomeres in mitosis: organization and dynamics. [PDF]

Nucleus
La Torre M, Fabiano S, Burla R, Saggio I.   +3 more
europepmc   +1 more source