Results 51 to 60 of about 53,083 (269)
Altered stability of nuclear lamin-B marks the onset of aging in male Drosophila.
PLoS ONE, 2022 Epigenetic alterations occur during aging, but it remains unclear what epigenetic features are associated with the onset of physiological decline in animals.
Wei-Qi Lin +3 more
doaj +1 more source
Altered protein dynamics of disease-associated lamin A mutants
BMC Cell Biology, 2004 Background Recent interest in the function of the nuclear lamina has been provoked by the discovery of lamin A/C mutations in the laminopathy diseases. However, it is not understood why mutations in lamin A give such a range of tissue-specific phenotypes.
Worman Howard J +5 more
doaj +1 more source
Unicritical and Maximally Critical Laminations [PDF]
arXiv, 2023 We study the correspondence between unicritical laminations and maximally critical laminations with rotational and identity return polygons. Laminations are a combinatorial and topological way to study Julia sets. Laminations give information about the structure of parameter space of degree $d$ polynomials with connected Julia sets.
arxiv
Leafwise smoothing laminations [PDF]
Algebr. Geom. Topol. 1 (2001) 579-587, 2001 We show that every topological surface lamination of a 3-manifold M is isotopic to one with smoothly immersed leaves. This carries out a project proposed by Gabai in [Problems in foliations and laminations, AMS/IP Stud. Adv. Math. 2.2 1--33]. Consequently any such lamination admits the structure of a Riemann surface lamination, and therefore useful ...
arxiv +1 more source
Journal of Translational Medicine, 2023 Background Dilated cardiomyopathy (DCM) is a severe, non-ischemic heart disease which ultimately results in heart failure (HF). Decades of research on DCM have revealed diverse aetiologies.
Chia Yee Tan +12 more
doaj +1 more source
arXiv, 2023 Laminations are a combinatorial and topological way to study Julia sets. Laminations give information about the structure of parameter space of degree $d$ polynomials with connected Julia sets. We first study fixed point portraits in laminations and their respective global count.
arxiv
Frontiers in Cell and Developmental Biology, 2019 We recently identified lamin A/C as a docking molecule for human histone deacetylase 2 (HDAC2) and showed involvement of HDAC2-lamin A/C complexes in the DNA damage response.
Elisabetta Mattioli +11 more
doaj +1 more source
$\R$-trees and laminations for free groups III: Currents and dual $\R$-tree metrics [PDF]
Proc. of the London Math. Soc. 78 (2008) 755-766, 2007 This is the third of a series of three articles where we introduce laminations for the free-groups. We explore here the link between currents and laminations and prove that the situation is more complicated than in the surface case of real tree dual to a measured geodesic lamination.
arxiv +1 more source
Nature Communications, 2019 Mutations in LMNA, which encodes the nuclear proteins Lamin A/C, can cause cardiomyopathy and conduction disorders. Here, we employ induced pluripotent stem cells (iPSCs) generated from human cells carrying heterozygous K219T mutation on LMNA to develop ...
semanticscholar +1 more source
Structural basis for lamin assembly at the molecular level
Nature Communications, 2019 Nuclear structure and function are governed by lamins, which are intermediate filaments that mostly consist of α-helices. Different lamin assembly models have been proposed based on low resolution and fragmented structures.
Jinsook Ahn +8 more
semanticscholar +1 more source