Results 11 to 20 of about 41,627 (225)
A novel role of lamins from genetic disease to cancer biomarkers
Oncology Reviews, 2016 Lamins are the key components of the nuclear lamina and by virtue of their interactions with chromatin and binding partners act as regulators of cell proliferation and differentiation.
Kunnathur Murugesan Sakthivel +1 more
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Lamin C is required to establish genome organization after mitosis
Genome Biology, 2021 Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery.
Xianrong Wong +5 more
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PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
Cells, 2020 Lamin A/C has been implicated in the epigenetic regulation of muscle gene expression through dynamic interaction with chromatin domains and epigenetic enzymes. We previously showed that lamin A/C interacts with histone deacetylase 2 (HDAC2).
Spartaco Santi +4 more
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GENDER FEATURES OF LAMINA CONTENT IN HUMAN SKIN FIBROBLASTS IN A PROCESS OF CHRONOLOGICAL AGING
Сибирский научный медицинский журнал, 2019 The purpose of the study was to investigate gender peculiarities of the content of fibroblasts immunopositive to lamins A, B1 and B2 in skin samples in a process of chronological aging. Material and methods.
N. N. Golubtsova +2 more
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Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells. [PDF]
PLoS ONE, 2017 Nuclear lamins support the nuclear envelope and provide anchorage sites for chromatin. They are involved in DNA synthesis, transcription, and replication.
Ines Rauschert +7 more
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Regulation of Lipid Metabolism by Lamin in Mutation-Related Diseases
Frontiers in Pharmacology, 2022 Nuclear lamins, known as type 5 intermediate fibers, are composed of lamin A, lamin C, lamin B1, and lamin B2, which are encoded by LMNA and LMNB genes, respectively.
Yue Peng +4 more
doaj +1 more source
The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence [PDF]
Open Biology, 2016 AKTIP is a shelterin-interacting protein required for replication of telomeric DNA. Here, we show that AKTIP biochemically interacts with A- and B-type lamins and affects lamin A, but not lamin C or B, expression.
Romina Burla +14 more
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Nucleus, 2019 Lamin A, a product of the LMNA gene, is an essential nuclear envelope component in most differentiated cells. Mutations in LMNA have been linked to premature aging disorders, including Hutchinson-Gilford progeria syndrome (HGPS).
Magda R. Hamczyk, Vicente Andrés
doaj +1 more source
Expression of Lamin A gene in periodontitis: A cross-sectional study [PDF]
Journal of Advanced Periodontology and Implant DentistryBackground. The host defense process against invading bacteria leads to the destruction of the periodontium. Lamin A is an important protein for protecting DNA and preventing premature cell aging.
Naser Sargolzaie +5 more
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Annually laminated speleothems: a review
International Journal of Speleology, 2008 This review of annually laminated speleothems firstly considers the four types of annual laminae found within speleothems: fluorescentlaminae formed by annual variations in organic matter flux; visible or petrographic laminae, formed by annual variations in calcitetexture or fabric; calcite-aragonite couplets; and finally trace element laminae.
Baker, Andy +5 more
openaire +4 more sources