Results 191 to 200 of about 21,188,703 (341)

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

Cell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen, Shuo Liu, Le‐Yi Tu, Ming‐Mei Yang, Cong‐Wang Xu, Yue Jiang, Hui Yang, Chen‐Xu Tai, Yan‐Ning Wang, Yuan‐Yuan Xie, Ping‐Ping Shen, Bin Wang   +11 more
wiley   +1 more source

High matrix stiffness promotes senescence of type II alveolar epithelial cells by lysosomal degradation of lamin A/C in pulmonary fibrosis

Respiratory Research
Background Cellular senescence is one of the key steps in the progression of pulmonary fibrosis, and the senescence of type II alveolar epithelial cells (AEC IIs) may potentially accelerate the progression of pulmonary fibrosis.
Junhui Ba, Changyu Zheng, Yimei Lai, Xin He, Yuxi Pan, Yanqiu Zhao, Huihui Xie, Benquan Wu, Xiao Deng, Nan Wang   +9 more
doaj   +1 more source

Internal iamin structures within G1 nuclei of human dermal fibroblasts [PDF]

, 1993
The nuclear lamina is a mesh-like network of fibres subjacent to the inner nuclear membrane that is believed to be involved in the specific spatial reorganisation of chromatin after mitosis.
Bridger, JM, Hutchison, CJ, Kill, IR, O’Farrell, M   +3 more
core  

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

111 Single cell RNA seq revealed altered cytoskeletal dynamics and the formation of cytoplasmic RNA-Lamin A bodies during keratinocyte terminal differentiation [PDF]

, 2021
Duncan Wotherspoon, Clare Rogerson, R. O’Shaughnessy   +2 more
openalex   +1 more source

Lamin-A/C [PDF]

, 2020
openaire   +1 more source

Overloading Laminitis - A Comparison to other systemic laminities

Pferdeheilkunde Equine Medicine, 1999
K-D Budras, B Huskamp
openaire   +2 more sources

Unveiling Propriety, Validity and Consensus: A Multi‐level Examination of Legitimacy Following the Global Financial Crisis

Journal of Management Studies, EarlyView.
Abstract Previous work on legitimacy has conceptualized its multi‐level nature, encompassing individual‐level propriety and collective‐level validity. Recently, scholars have introduced the construct of consensus, the degree to which evaluators agree in terms of their propriety beliefs.
Patrick Haack, Jost Sieweke, Michael D. Pfarrer   +2 more
wiley   +1 more source

Mandibuloacral Dysplasia Is Caused by a Mutation in LMNA-Encoding Lamin A/C [PDF]

, 2002
Giuseppe Novelli, Antoine Muchir, Federica Sangiuolo, A. Leclerc, Maria Rosaria D’Apice, Catherine Massart, Francesca Capon, Paolo Sbraccia, Massimo Federici, Renato Lauro, Cosimo Tudisco, R Pallotta, Gioacchino Scarano, Bruno Dallapiccola, Luciano Merlini, Gisèle Bonne   +15 more
openalex   +1 more source