Results 41 to 50 of about 28,276 (143)
Journal of Infection in Developing Countries, 2011 Introduction: Perinatal transmission - from mother to fetus - is one of the main transmission routes of chronic hepatitis B (CHB) infection. Lamivudine therapy has been reported to prevent the replication of hepatitis B virus (HBV) in pregnant women ...
Sükran Köse +3 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 7, Page 945-954, April 2026.Current first‐line NUCs show comparable renal safety profiles in CHB patients with no or mild kidney dysfunction, with growing evidence that favours TAF. Future prospective studies are needed to validate these findings, and more research should focus on CHB patients with diabetes mellitus who are at risk of CKD.
Lung‐Yi Mak +2 more
wiley +1 more source
Journal of Viral Hepatitis, Volume 33, Issue 4, April 2026.ABSTRACT Since there are currently few antiviral drugs that can effectively reduce hepatitis B surface antigen levels, the recurrence rate remains high in patients with chronic hepatitis B (CHB) after discontinuing nucleoside analogues (NAs) treatment.
Dong‐Hui Wang +8 more
wiley +1 more source
Tenofovir as Rescue Therapy Following Clinical Failure to Lamivudine in Severe Acute Hepatitis B
Mediterranean Journal of Hematology and Infectious Diseases, 2013 Acute hepatitis B (AHB) is a self-limiting condition in more than 95% of cases. Treatment is however recommended in patients with severe AHB (
Jurgen Gerada +4 more
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Self‐Immolative Systems in Diagnostic and Therapeutic Applications
ChemMedChem, Volume 21, Issue 5, 13 March 2026.Self‐Immolative Systems enable the precise, residue‐free release of active molecules, drugs, probes, or sensors, via cyclization or elimination, triggered by specific stimuli. Their versatility drives advances in drug delivery, diagnostics, nanotechnology, materials chemistry, and biosensing, offering chemists control over molecular activation and ...
Windbedema Prisca Ouédraogo +2 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 3, March 2026.ABSTRACT Background Palliative care is essential to manage symptoms and end‐of‐life (EOL) quality, yet its utilisation in liver cancer remains poorly understood. This study examined sociodemographic and clinical characteristics associated with palliative care admission in the last 5 years of life for people with a death from liver cancer.
Rebecca J. Mitchell +5 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 3, March 2026.ABSTRACT In HIV‐positive patients, a blunted inflammatory response can mask retrorenal appendicitis, leading to atypical flank or abdominal pain. We report a case of dual pathology on CT scan involving retrorenal appendicitis and a large renal mass with a central scar suggesting oncocytoma.
Mohammed Salah E. Khalifa Salem +4 more
wiley +1 more source
Clinical &Translational Immunology, Volume 15, Issue 3, 2026.Depicts the pathways and mechanisms of the drug. Abstract Objectives Aicardi–Goutières syndrome (AGS) is a rare genetic interferonopathy because of aberrant DNA or RNA metabolism that lacks effective disease modifying therapies. Methods Single‐cell RNA sequencing was performed on peripheral blood mononuclear cells (PBMCs) obtained from a patient with ...
Velda X Han +12 more
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Química Nova, 2007 An HPLC method was validated to assay lamivudine and zidovudine combined in tablets. The chromatographic separation was carried out using methanol and acetate buffer pH 6.5 (50:50 v/v) and a RP-18 column, as mobile and stationary phase, respectively. The
Ruy Carlos Ruver Beck +5 more
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