Results 41 to 50 of about 252,737 (261)

Classification of Automated Lane-Change Styles by Modeling and Analyzing Truck Driver Behavior: A Driving Simulator Study

IEEE Open Journal of Intelligent Transportation Systems, 2022
Lane change is a highly demanding driving task. A number of traffic accidents are induced by erroneous maneuvers. An automated lane-change system has the potential to reduce the driver workload and improve driving safety.
Zheng Wang, Muhua Guan, Jin Lan, Bo Yang, Tsutomu Kaizuka, Junichi Taki, Kimihiko Nakano   +6 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Discretionary Lane-Change Decision and Control via Parameterized Soft Actor–Critic for Hybrid Action Space

Machines
This study focuses on a crucial task in the field of autonomous driving, autonomous lane change. Autonomous lane change plays a pivotal role in improving traffic flow, alleviating driver burden, and reducing the risk of traffic accidents. However, due to
Yuan Lin, Xiao Liu, Zishun Zheng
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Study on Lane-Change Replanning and Trajectory Tracking for Intelligent Vehicles Based on Model Predictive Control

World Electric Vehicle Journal, 2023
When an intelligent vehicle changes lanes, the state of other vehicles may change, which increases the risk of collision. Therefore, real-time local path replanning is needed at this time. Based on model predictive control (MPC), a lane-change trajectory
Yaohua Li, Dengwang Zhai, Jikang Fan, Guoqing Dong   +3 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Research on Safety Lane Change Warning Method Based on Potential Angle Collision Point

Journal of Advanced Transportation, 2019
In order to ensure safe lane change and avoid traffic accidents, an effective lane change assist system is required. In a lane change assist system, it is very important to obtain the following elements in time, such as actual distance between vehicles ...
Tongqiang Ding, Xiaorong Li, Lili Zheng, Zhiguo Hao   +3 more
doaj   +1 more source

Pay to change lanes: A cooperative lane-changing strategy for connected/automated driving [PDF]

Transportation Research Part C: Emerging Technologies, 2019
This paper proposes a cooperative lane changing strategy using a transferable utility games framework. This allows vehicles to engage in transactions where gaps in traffic are created in exchange for monetary compensation. The proposed approach is best suited to discretionary lane change maneuvers. We formulate gains in travel time, referred to as time
Dianchao Lin, Li Li, Saif Eddin Jabari
openaire   +2 more sources