Results 31 to 40 of about 54,165 (256)

Capturing Drivers’ Lane Changing Behaviors on Operational Level by Data Driven Methods

IEEE Access, 2018
With the development of autonomous vehicles, advanced driver-assistance systems, and vehicular social networks, the requirement for vehicle trajectory prediction in lane changing is higher.
Ling Huang, Hengcong Guo, Ronghui Zhang, Haiwei Wang, Jianping Wu   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Mathematical Modeling and Parameter Estimation of Lane-Changing Vehicle Behavior Decisions

Mathematics
Lane changing is a crucial scenario in traffic environments, and accurately recognizing and predicting lane-changing behavior is essential for ensuring the safety of both autonomous vehicles and drivers.
Jianghui Wen, Yebei Xu, Min Dai, Nengchao Lyu   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Active Lane-Changing Control of Intelligent Vehicle on Curved Section of Expressway

Modelling and Simulation in Engineering, 2022
In order to improve the intelligent vehicle lane-changing performance, an active lane-changing control algorithm is proposed considering the changes of road curvature and vehicle speed.
Pengfei Feng, Huiqing Jin, Linfeng Zhao, Mingyu Lu   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Target Vehicle Selection Algorithm for Adaptive Cruise Control Based on Lane-changing Intention of Preceding Vehicle

Chinese Journal of Mechanical Engineering, 2021
To improve the ride comfort and safety of a traditional adaptive cruise control (ACC) system when the preceding vehicle changes lanes, it proposes a target vehicle selection algorithm based on the prediction of the lane-changing intention for the ...
Jun Yao, Guoying Chen, Zhenhai Gao
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Influencing Factors of the Length of Lane-Changing Buffer Zone for Autonomous Driving Dedicated Lanes

Applied Sciences, 2022
With the development of intelligent transportation, dedicated highway lanes for autonomous vehicles (AVs), necessary for ensuring their right of way, have emerged as critical issues in intelligent transportation research, which makes it necessary to set ...
Fujin Hou, Ying Zhang, Shujian Wang, Zhengxi Shen, Peipei Mao, Xu Qu   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source