Results 51 to 60 of about 1,897,464 (299)

Lane County Public Health Authority Comprehensive Plan [PDF]

open access: yes, 2010
71 pp. Charts, tables.The Comprehensive Plan submitted for FY 2010-2011 for Lane County includes the following narrative sections: an assessment which provides demographic and public health indicators for Lane County; a description of the delivery of ...
Lane County (Or.)
core   +1 more source

A state dependent mandatory lane-changing model for urban arterials with hidden markov model method

open access: yesInternational Journal of Transportation Science and Technology, 2019
The inherent intention and decision process of lane changes are complex. Though the external environment and traffic conditions are changing along the traveling direction, the drivers’ characteristics and preferences may lead to persistence of preferable
Xiduo Wang, Yunlong Zhang, Jian Jiao
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

Exploring Sustainable Lane-Change Behaviours – Integrated Approach to Modelling Mixed Traffic with Intelligent-Connected Vehicles

open access: yesPromet (Zagreb)
This paper proposes two sustainable lane-changing (LC) decision-making models for application in intelligent-connected (I-C) and mixed-traffic environments.
Xushan FANG   +6 more
doaj   +1 more source

Research on Decision-Making Behavior of Discretionary Lane-Changing Based on Cumulative Prospect Theory

open access: yesJournal of Advanced Transportation, 2020
In this paper, the decision-making model of discretionary lane-changing is established using cumulative prospect theory (CPT). Through analyzing the vehicles’ dynamic running states, safety spacing calculating approaches for discretionary lane-changing ...
Xueqin Long   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Modeling collision risk for unsafe lane-changing behavior: A lane-changing risk index approach

open access: yesAlexandria Engineering Journal
The lane-changing maneuvers are challenging and contributes to traffic accidents and crashes. They are complicated task that often lead to an increased risk of vehicle collisions and deteriorates traffic flow. This paper proposes a vehicle collision risk
Muhammad Sameer Sheikh, Yinqiao Peng
doaj   +1 more source

A Novel Dynamic Lane-Changing Trajectory Planning Model for Automated Vehicles Based on Reinforcement Learning

open access: yesJournal of Advanced Transportation, 2022
Lane changing behavior has a significant impact on traffic efficiency and may lead to traffic delays or even accidents. It is important to plan a safe and efficient lane-changing trajectory that coordinates with the surrounding environment.
Cenxin Yu   +6 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

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