Results 121 to 130 of about 10,482,646 (332)

Langerhans cell histiocytosis

open access: yes, 2013
Definition: A histiocytary proliferation of granuloma-like aspect with unknown etiology that may involve bone marrow, internal organs, skin, and mucosae.
openaire   +4 more sources

Recurrent adult-onset hypophyseal Langerhans cell histiocytosis after radiotherapy: A case report [PDF]

open access: yes, 2012
INTRODUCTION: Langerhans cell histiocytosis is a rare disease within the adult population, with very few cases reported as solitary hypophyseal lesions in adults.
Chicoine, Michael R   +8 more
core   +2 more sources

Recurrent BRAF mutations in Langerhans cell histiocytosis.

open access: yesBlood, 2010
Langerhans cell histiocytosis (LCH) has a broad spectrum of clinical behaviors; some cases are self-limited, whereas others involve multiple organs and cause significant mortality.
G. Badalian‐Very   +14 more
semanticscholar   +1 more source

Skin‐Derived PGD2 Promotes Antigen‐Specific IgE Production via CRTH2 Signaling

open access: yes
Allergy, EarlyView.
Misato Kida   +5 more
wiley   +1 more source

Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation.

open access: yesBlood, 2013
Histiocytoses are rare disorders of unknown origin with highly heterogeneous prognosis. BRAFV600E gain-of-function mutations have been observed in 57% of cases of Langerhans cell histiocytosis (LCH) and 54% of cases of Erdheim-Chester disease (ECD), but ...
J. Haroche   +12 more
semanticscholar   +1 more source

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio   +1 more
wiley   +1 more source

Implication of Perifollicular Clusters and Folliculotropic Distribution of Dendritic Cells in the Pathogenesis of Seborrhoeic Dermatitis

open access: yesActa Dermato-Venereologica, 2020
The pathogenesis of seborrhoeic dermatitis is controversial and remains unclear. Malassezia is considered to be a commensal fungi and is found not only in the stratum corneum but also in hair follicles. It is an important pathogenic factor in seborrhoeic
Ayako Ito   +3 more
doaj   +1 more source

Resting respiratory tract dendritic cells preferentially stimulate T helper cell Type 2(Th2) responses and require obligatory cytokine signals for induction of Th1 immunity [PDF]

open access: yes, 1998
Consistent with their role in host defense, mature dendritic cells (DCs) from central lymphoid organs preferentially prime for T helper cell type 1 (Th1)-polarized immunity.
Holt, P.G.   +6 more
core   +2 more sources

Therapy prolongation improves outcome in multisystem Langerhans cell histiocytosis.

open access: yesBlood, 2013
Langerhans cell histiocytosis (LCH)-III tested risk-adjusted, intensified, longer treatment of multisystem LCH (MS-LCH), for which optimal therapy has been elusive.
H. Gadner   +14 more
semanticscholar   +1 more source

Aural plaques: Considerations on autohaemotherapy treatment in four Mangalarga Marchador crossbred horses

open access: yesEquine Veterinary Education, EarlyView.
Summary The occurrence of Aural Plaques (AP) in horses, attributed to infection with Equus caballus Papillomavirus (EcPV), has become increasingly prevalent in equine breeding populations. Major challenges in managing this condition include genetic susceptibility to the virus, significant variability in individual immune responses among horses and the ...
E. Bastianetto   +6 more
wiley   +1 more source

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