Results 121 to 130 of about 10,554,839 (372)

CD1a on Langerhans cells controls inflammatory skin diseases

open access: yesNature Immunology, 2016
CD1a is a lipid-presenting molecule that is abundantly expressed on Langerhans cells. However, the in vivo role of CD1a has remained unclear, principally because CD1a is lacking in mice.
Ji Hyung Kim   +11 more
semanticscholar   +1 more source

Microneedle delivery systems for vaccines and immunotherapy

open access: yesSmart Molecules, EarlyView.
This paper reviews the preparation methods and materials of microneedles for drug delivery, summarizes the structures and types of microneedle systems, analyzes the influence of antigens and adjuvants on the efficacy of microneedle vaccines, and reviews the current application status of microneedles in the fields of vaccines and immunotherapy by ...
Haiyao Jia   +5 more
wiley   +1 more source

Skull Base Langerhans Cell Histiocytosis with Diabetes Insipidus and Panhypopituitarism- A Rare Clinical Entity

open access: yesBengal Journal of Otolaryngology and Head Neck Surgery, 2017
Introduction A case of Langerhans cell histiocytosis (LGH) involving extensive area of base of skull resulting in panhypopituitarism and diabetes insipidus (DI) is reported.
Anirban Ghosh   +2 more
doaj   +1 more source

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas [PDF]

open access: yes, 2000
Differentiation of early gut endoderm cells into the endocrine cells forming the pancreatic islets of Langerhans depends on a cascade of gene activation events controlled by transcription factors including the basic helix-loop-helix (bHLH) proteins.
Anderson, David J.   +8 more
core  

Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]

open access: yes, 1993
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry   +19 more
core   +1 more source

Langerhans Cell Histiocytosis

open access: yesSurvey of Ophthalmology, 2008
The clinical manifestations of Langerhans cell histiocytosis have been recognized for more than a century. For most of that time, physicians have viewed the disease from different perspectives, interpreting portions of its clinical spectrum as if they were distinct and unrelated entities.
Department of Ophthalmology and Pathology, University of South Florida, College of Medicine, and Section of Ophthalmology James A. Haley Veterans Hospital, Tampa, Florida, USA ( host institution )   +2 more
openaire   +4 more sources

Otic Langerhans' Cell Histiocytosis in an Adult: A Case Report and Review of the Literature

open access: yesCase Reports in Otolaryngology, 2013
Objective. To present a case of otic Langerhans' cell histiocytosis in an adult. Also included the diagnosis and management of the condition and a review of the relevant literature. Case Report.
Anil Gungadeen   +2 more
doaj   +1 more source

Langerhans Cell Modulation in Atopic Dermatitis Is TLR2/SOCS1‐Dependent and JAK Inhibitor‐Sensitive

open access: yesAllergy, EarlyView.
Constitutive exposure to TLR2 ligands can modify Langerhans cell (LC) activation capacity and outcome, being similar to LC in atopic dermatitis skin. While maturation marker and migration are impaired, the cytokine profile switches and favors atopic dermatitis‐related IL‐1β and IL‐18.
Yuxuan Deng   +6 more
wiley   +1 more source

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

open access: yesAndrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch   +6 more
wiley   +1 more source

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