Results 11 to 20 of about 10,482,646 (332)
Langerhans cell histiocytosis [PDF]
Blood, 2020 Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
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Indian Journal of Medical Research, 2018 Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
Anil S Menon, Manish Kumar
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Journal of Medical Case Reports, 2021 Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
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Langerhans cell histiocytosis developing acute lymphoblastic leukemia
SAGE Open Medical Case Reports, 2022 The sequential occurrence of Langerhans cell histiocytosis and acute leukemia in only one individual has been reported previously; however, it is rarely observed that Langerhans cell histiocytosis can transform into acute lymphoblastic leukemia, and the ...
JinFang Zhang, Sa Zong, Bing Liao
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Definitions, 2020 Dendritic clear cells in the epidermis, containing distinctive granules that appear rodor racket-shaped in section, but lacking tonofilaments, melanosomes, and desmosomes; they carry surface receptors for immunoglobulin (Fc) and complement (C3), and are ...
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Journal of Contemporary Medicine, 2022 Scabies is an infestation caused by the Sarcoptes scabiei burrowing into the epidermis. Histopathologically scabies infestation may reveal Langerhans cell hyperplasia which might cause misdiagnosis of Langerhans cell histiocytosis in some cases.
Ayşe Esra Koku Aksu +5 more
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Activation Pattern of Langerhans Cells in the Afferent and Efferent Phases of Contact Hypersensitivity [PDF]
, 1999 Langerhans cells are MHC class II (Ia) positive antigen- presenting cells that play a crucial role in the induction of contact hypersensitivity (CHS).
Araki, Mikio +4 more
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Rare Tumors, 2017 Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis.
Alejandro Peralta Soler +2 more
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Lymphangiogenesis and angiogenesis during human fetal pancreas development [PDF]
, 2014 Background: The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in the physiology of the pancreas and
Carlotti, Françoise +6 more
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Langerhans cell histiocytosis in adults: Advances in pathophysiology and treatment
Cancer Science, 2018 Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the accumulation of CD1a+/Langerin+ LCH cells and wide‐ranging organ involvement.
Masayuki Kobayashi, A. Tojo
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