Results 61 to 70 of about 149,549 (315)
A Case of Multisystemic Langerhans Cell Histiocytosis in an Adult
Proceedings of Singapore Healthcare, 2011 Langerhans cell histiocytosis is a rare disease in adults with a myriad of clinical presentations. A case of multisystemic Langerhans cell histiocytosis with involvement of bone, skin, lungs, and the hypothalamic-pituitary-axis is reported.
Chiaw Ling Chng MBBS, MRCP
doaj +1 more source
The role of Microenvironment in tumorigenesis. Focus on dendritic cells in human papillomavirus E6, E7-transformed keratinocytes [PDF]
, 2015 The inception of tumor microenvironment (TME), a complex and dynamic system constituted by different types of cells engaged by tumor and extracellular matrix surrounding cancer cells, is a way for them to elude the immune surveillance.
Accardi, Rosita +6 more
core +1 more source
Pathophysiology of Langerhans cells
Journal of Oral and Maxillofacial Pathology, 2012 Langerhans cells (LCs) were first described by Paul Langerhans, in 1868, as dendritically shaped cells, which were located in the squamous epithelia of epidermis. Later on, these cells were identified in all stratified squamous epithelium of mammals. Dendritic cells (DCs) play an important role in local defense mechanisms in the epithelium.
Shweta Jaitley, TR Saraswathi
openaire +4 more sources
On the coherent behavior of pancreatic beta cell clusters [PDF]
, 2014 Beta cells in pancreas represent an example of coupled biological oscillators which via communication pathways, are able to synchronize their electrical activity, giving rise to pulsatile insulin release. In this work we numerically analyze scale free self-similarity features of membrane voltage signal power density spectrum, through a stochastic ...
arxiv +1 more source
Revista Brasileira de Ginecologia e Obstetrícia, 2004 OBJETIVOS: estudar a relação dos fatores biocomportamentais (idade, menarca, número de gestações e precocidade sexual) com alterações das células de Langerhans em mulheres com captura híbrida negativa para HPV.
Nelson Shozo Uchimura +4 more
doaj +1 more source
Solitary Langerhans cell histiocytosis of liver with sclerosing cholangitis in an adult female [PDF]
, 2017 Liver is affected as a late complication of high risk cases of Langerhans cell histiocytosis. Sclerosing cholangitis is a rare pattern associated with Langerhans cell histiocytosis of liver, which is even rarer in the adult population and has high ...
Kader, Nazneen A. +2 more
core +2 more sources
FEBS Open Bio, EarlyView.T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang +5 more
wiley +1 more source
Development of extrahepatic bile ducts and mechanisms of tumorigenesis: Lessons from mouse models
Pathology International, Volume 72, Issue 12, Page 589-605, December 2022., 2022 Abstract The biliary system is a highly branched tubular network consisting of intrahepatic bile ducts (IHBDs) and extrahepatic bile ducts (EHBDs). IHBDs are derived from hepatic progenitor cells, while EHBDs originate directly from the endoderm through a separate branching morphogenetic process.
Hiroyuki Tomita, Akira Hara
wiley +1 more source
Surface activity of cancer cells: the fusion of two cell aggregates [PDF]
arXiv, 2021 Although a good comprehension of how cancer cells collectively migrate by following molecular rules which influence the state of cell-cell adhesion contacts has been generated, the impact of collective migration on cellular rearrangement from subcellular to supracellular level remains less understood.
arxiv
Cell-to-cell variation sets a tissue-rheology-dependent bound on collective gradient sensing [PDF]
PNAS (2017), 2017 When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding to gradients, however, there is a critical difference: even genetically identical cells have differing responses to chemical signals.
arxiv +1 more source