Results 61 to 70 of about 10,554,839 (372)

Langerhans Cell Histiocytosis: An Unusual Presentation

Philippine Journal of Otolaryngology Head and Neck Surgery, 2008
Objective:  To describe an unusual presentation of Langerhans cell histiocytosis in the craniofacial skeleton in a patient previously diagnosed with Pott’s disease. Methods: Design: Case report. Setting:  Tertiary care center.  Patient: One
Kathleen R. Fellizar, Charlotte M. Chiong   +1 more
doaj   +1 more source

Ontogeny of Langerhans Cells

Journal of Investigative Dermatology, 1980
Results of transplantation and chimera studies indicate that epidermal Langerhans cells are derived from precursor cells originating bone marrow.
Kunihiko Tamaki, Stephen I. Katz
openaire   +3 more sources

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

A Case of Orbital Langerhans Cell Histiocytosis in an Adult

Acta Médica Portuguesa, 2019
Langerhans cell histiocytosis remains an enigmatic disease with a very heterogeneous presentation. We describe a rare case of orbital Langerhans cell histiocytosis in a 39-year-old female patient who presented right orbital pain and edema of the upper ...
Inês Carneiro, António Friande, Maria Araújo   +2 more
doaj   +1 more source

METTL3/ALKBH5‐Mediated N6‐Methyladenosine Modification Drives Macrophage M1 Polarization via the SLC15A3‐TASL‐IRF5 Signaling Axis in Psoriasis

Advanced Science, EarlyView.
m6A modification stabilizes Slc15a3 mRNA in macrophages, activating the SLC15A3‐TASL‐IRF5 axis and promoting psoriatic inflammation. Abstract Impaired N6‐methyladenosine (m6A) modification has been implicated in regulating various inflammatory diseases, but its role in psoriasis remains unclear.
Tao Huang, Shijun Chen, Ke Ding, Liyan Yuan, Weiqi Lv, Kechen Chen, Yuchen Liu, Dongzhao Ma, Xin Zhang, Xiaobo Wang, Guanzheng Luo, Bin Yang, Ying Lin, Zhili Rong   +13 more
wiley   +1 more source

In Vivo Imaging of Transplanted Islets with ^(64)Cu-DO3A-VS-Cys^(40)-Exendin-4 by Targeting GLP-1 Receptor [PDF]

, 2011
Glucagon-like peptide 1 receptor (GLP-1R) is highly expressed in pancreatic islets, especially on β-cells. Therefore, a properly labeled ligand that binds to GLP-1R could be used for in vivo pancreatic islet imaging.
Bading, James R., Colcher, David, Conti, Peter E., Fraser, Scott E., Ishiyama, Kohei, Kandeel, Fouad, Li, Lin, Li, Zibo, Nair, Indu, Shively, John E., Todorov, Ivan, Wu, Zhanhong   +11 more
core   +2 more sources

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

PULMONARY AND INTRACRANIAL RADIOGRAPHIC PRESENTATIONS OF LANGERHANS CELL HISTIOCYTOSIS

International Journal of Medicine and Medical Research, 2019
Background. Langerhans Cell Histiocytosis is a rare disease that affects 1 to 2 adults per million worldwide and often consists of systemic manifestations including pulmonary, intracranial and osteolytic lesions and endocrinologic abnormalities such as ...
D. Mohammed, S. B. Patel
doaj   +1 more source

Immunological characterization of chromogranins A and B and secretogranin II in the bovine pancreatic islet [PDF]

, 1987
Antisera against chromogranin A and B and secretogranin II were used for analysing the bovine pancreas by immunoblotting and immunohistochemistry. All three antigens were found in extracts of fetal pancreas by one dimensional immunoblotting. A comparison
A Iacangelo, AD Smith, BS Wilson, C Hagn, D Grube, D Grube, D Grube, DT O'Connor, DT O'Connor, DV Cohn, E El-Nady, FU Reiffen, FU Reiffen, G Falkensammer, G Falkensammer, G Rindi, H Blaschko, H Lassmann, H Winkler, HD Mayor, IM Varndell, JA Nolan, JC Hutton, K Tatemoto, KB Helle, KB Helle, L Kilpatrick, LA Sternberger, LE Eiden, M Ehrhart, M Ravazzola, P Rosa, PH O'Farell, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, RV Floyd, S Bonner-Weir, S Lenzen, UK Laemmli, UM Benedum, WB Huttner, WJ Smith, WN Burnette   +44 more
core   +1 more source