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Since Langerhans (1) first described the presence of gold-positive dendritic cells in the epidermis, their nature has been an unsettled question. These cells, which morphologically resemble melanocytes, are free of pigment and are not seen when stained for melanin nor when the dopa stain is used; but they can be demonstrated with gold chloride methods.
Alvin S. Zelickson
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Trauma of Peripheral Innervation Impairs Content of Epidermal Langerhans Cells [PDF]
Langerhans cells represent the first immune cells that sense the entry of external molecules and microorganisms at the epithelial level in the skin. In this pilot case-study, we evaluated Langerhans cells density and progression of epidermal atrophy in ...
Giovanna Albertin+10 more
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Immunohistochemical analysis of S100-positive epidermal Langerhans cells in dermatofibroma, [PDF]
Dermatofibroma is a dermal fibrohistiocytic neoplasm. The Langerhans cells are the immunocompetent cells of the epidermis, and they represent the first defense barrier of the immune system towards the environment.
Mahmoud Rezk Abdelwhaed Hussein
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Langerhans cell histiocytosis [PDF]
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentine, but the diagnosis was done with the demonstration of Birbeck granules with ...
Chauffaille, Maria de Lourdes Lopes Ferrari UNIFESP+10 more
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Langerhans cells are the bone-marrow-derived immune cells of the epidermis; they express Ia antigens and receptors for the Fc portion of IgG and complement components and are required for epidermal-cell-induced antigen-specific, syngeneic and allogeneic T-cell activitation and the generation of epidermal-cell-induced cytotoxic T cells.
Georg Stingl, Klaus Wolff
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Langerhans cells in keratoacanthoma
Yang-Che Wu+3 more
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LANGERHANS CELLS HISTIOCYTOSIS
Langerhans cell histiocytosis (LCH) merupakan salah satu penyakit terbanyak dari histiositosis dengan 2,0–5,4 kasus/100 juta populasi diseluruh dunia ...
Krisna Murti, Maria Ulfa
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We presented a case of diffuse-type tenosynovial giant cell tumour (DTSGCT) of foot masquerading as Langerhans cell histiocytosis. Preliminary diagnosis by needle biopsy was difficult due to the major involvement of bones and the overshadowing effect of ...
Florence M. F. Cheung+3 more
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Langerhans cell sarcoma of the skin is a rare tumor with aggressive behavior. There are reports of Langerhans cell sarcoma involving the skin in patients with underlying systemic Langerhans cell histiocytosis.
Alejandro Peralta Soler+2 more
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The current understanding on langerhans' cells and its role in oral lesions
Objective: Description of Langerhans' cells (LCs) as an important antigen-presenting cells responsible for detecting the antigens, recruiting T-cells, and thereby initiating the immune response.
Vidyadevi Chandavarkar+3 more
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