Trauma of Peripheral Innervation Impairs Content of Epidermal Langerhans Cells [PDF]
Diagnostics, 2022 Langerhans cells represent the first immune cells that sense the entry of external molecules and microorganisms at the epithelial level in the skin. In this pilot case-study, we evaluated Langerhans cells density and progression of epidermal atrophy in ...
Giovanna Albertin +10 more
doaj +2 more sources
Influência do uso de anticoncepcionais hormonais orais sobre o número de células de Langerhans em mulheres com captura híbrida negativa para papilomavírus humano Langerhans' cells: influence of the of oral contraceptives by women with negative hybrid capture for human papillomavirus [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2005 OBJETIVO: estudar a influência do uso de anticoncepcionais orais (AO) sobre o número de células de Langerhans em mulheres sem infecção cervical por papilomavírus humano (HPV).
Nelson Shozo Uchimura +4 more
doaj +5 more sources
Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission [PDF]
Nature CommunicationsArthropods are ancient vectors of infectious disease that alter the immune environment of the skin during feeding. The epidermis and its immune sentinels, including Langerhans cells, are critical for protection against ectoparasitic arthropods such as ...
Johanna Strobl +15 more
doaj +2 more sources
Langerhans cell histiocytosis on the penis: a case report [PDF]
BMC Urology, 2006 Background Langerhans cell histiocytosis affects mainly young children and features an accumulation of CD1a+ dendritic Langerhans cells in the bone, skin, and other organs.
Kuroda Isao +5 more
doaj +2 more sources
Sphingosine 1-phosphate modulates antigen capture by murine langerhans cells via the S1P2 receptor subtype [PDF]
, 2012 Dendritic cells (DCs) play a pivotal role in the development of cutaneous contact hypersensitivity (CHS) and atopic dermatitis as they capture and process antigen and present it to T lymphocytes in the lymphoid organs.
A Kihara +68 more
core +16 more sources
Langerhans cell histiocytosis [PDF]
Indian Journal of Medical Research, 2018 Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and now called Langerhans-cell histiocytosis is characterized by ERK pathway activation (including BRAF V600E ...
Kumar, Manish, Menon, Anil S
openaire +4 more sources
Hepatic Langerhans cell histiocytosis: Report of a rare case
Human Pathology Reports, 2023 Langerhans cell histiocytosis (LCH) is a rare neoplastic disease characterized by abnormal proliferation of Langerhans cells infiltrating various organs, resulting in organ dysfunction.
Renling Yao, Jun Chen, Jie Li
doaj +1 more source
Langerhans cell histiocytosis [PDF]
Blood, 2020 Abstract Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction. The pathogenic cells are defined by constitutive activation of the MAPK signaling pathway.
Carl E. Allen, Carlos Rodriguez-Galindo
openaire +2 more sources
Langerhans Cell Histiocytosis [PDF]
Cancer Control, 2014 Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
Giovannetti, Filippo +7 more
openaire +7 more sources
Case Reports in Medicine, 2022 We presented a case of diffuse-type tenosynovial giant cell tumour (DTSGCT) of foot masquerading as Langerhans cell histiocytosis. Preliminary diagnosis by needle biopsy was difficult due to the major involvement of bones and the overshadowing effect of ...
Florence M. F. Cheung +3 more
doaj +1 more source