Results 21 to 30 of about 101,166 (275)

Enhanced mechanical heterogeneity of cell collectives due to temporal fluctuations in cell elasticity [PDF]

open access: yesPhys. Rev. E 107, 014401 (2023), 2022
Cells are dynamic systems characterized by temporal variations in biophysical properties such as stiffness and contractility. Recent studies show that the recruitment and release of actin filaments into and out of the cell cortex - a network of proteins underneath the cell membrane - leads to cell stiffening prior to division and softening immediately ...
arxiv   +1 more source

Langerhans Cell Sarcoma: A Case Report Demonstrating Morphological and Immunophenotypical Variability within a Single Lesion

open access: yesCase Reports in Pathology, 2017
Langerhans cells are antigen presenting dendritic cells and tumours arising from these are rare. The tumours arising from these dendritic cells are divided into two categories according to a WHO classification: Langerhans cell histiocytosis and ...
Rasika Singh   +3 more
doaj   +1 more source

Microscopical Study of Pancreatic Tissue of Babirusa (Babyrousa babyrussa) Using Conventional and Immunohistochemical Methods

open access: yesJurnal Kedokteran Hewan, 2010
This study utilized conventional and immunohistochemical methods, to describe the morphology and distribution of glucagon and insulin cells in the pancreas of adult male babirusa (Babyrousa babyrussa).
Ketut Mudite Adnyane   +2 more
doaj   +1 more source

The Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells

open access: yesViruses, 2020
Three-dimensional cell culturing to capture a life-like experimental environment has become a versatile tool for basic and clinical research. Mucosal and skin tissues can be grown as “organoids” in a petri dish and serve a wide variety of research ...
Robert Jackson   +2 more
doaj   +1 more source

Fatores biocomportamentais e as alterações no número das células de Langerhans Behavioral factors and changes in the number of Langerhans' cells

open access: yesRevista Brasileira de Ginecologia e Obstetrícia, 2004
OBJETIVOS: estudar a relação dos fatores biocomportamentais (idade, menarca, número de gestações e precocidade sexual) com alterações das células de Langerhans em mulheres com captura híbrida negativa para HPV.
Nelson Shozo Uchimura   +4 more
doaj   +1 more source

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +1 more source

Shaping bursting by electrical coupling and noise [PDF]

open access: yesBiological Cybernetics Volume 106, Number 2 (2012), 67-88, 2011
Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations generated by an electrically coupled network may differ qualitatively from the oscillations produced by uncoupled ...
arxiv   +1 more source

Learning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive response [PDF]

open access: yesPLoS ONE 8(8): e70366 (2013), 2013
Cells of almost all solid tissues are connected with gap junctions which permit the direct transfer of ions and small molecules, integral to regulating coordinated function in the tissue. The pancreatic islets of Langerhans are responsible for secreting the hormone insulin in response to glucose stimulation.
arxiv   +1 more source

From simplicity to complexity in current melanoma models

open access: yesExperimental Dermatology, Volume 31, Issue 12, Page 1818-1836, December 2022., 2022
Abstract Despite the recent impressive clinical success of immunotherapy against melanoma, development of primary and adaptive resistance against immune checkpoint inhibitors remains a major issue in a large number of treated patients. This highlights the need for melanoma models that replicate the tumor's intricate dynamics in the tumor ...
Elisabetta Michielon   +2 more
wiley   +1 more source

The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on $\textrm{Ca}^{2+}$ dynamics [PDF]

open access: yes, 2020
Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of $\beta$-cell mass and alteration of $\beta$-cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in $\beta$-cell mass and function during the hyperglycemia development and T2D ...
arxiv   +1 more source

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