Results 21 to 30 of about 101,166 (275)
Enhanced mechanical heterogeneity of cell collectives due to temporal fluctuations in cell elasticity [PDF]
Cells are dynamic systems characterized by temporal variations in biophysical properties such as stiffness and contractility. Recent studies show that the recruitment and release of actin filaments into and out of the cell cortex - a network of proteins underneath the cell membrane - leads to cell stiffening prior to division and softening immediately ...
arxiv +1 more source
Langerhans cells are antigen presenting dendritic cells and tumours arising from these are rare. The tumours arising from these dendritic cells are divided into two categories according to a WHO classification: Langerhans cell histiocytosis and ...
Rasika Singh+3 more
doaj +1 more source
This study utilized conventional and immunohistochemical methods, to describe the morphology and distribution of glucagon and insulin cells in the pancreas of adult male babirusa (Babyrousa babyrussa).
Ketut Mudite Adnyane+2 more
doaj +1 more source
The Potentials and Pitfalls of a Human Cervical Organoid Model Including Langerhans Cells
Three-dimensional cell culturing to capture a life-like experimental environment has become a versatile tool for basic and clinical research. Mucosal and skin tissues can be grown as “organoids” in a petri dish and serve a wide variety of research ...
Robert Jackson+2 more
doaj +1 more source
OBJETIVOS: estudar a relação dos fatores biocomportamentais (idade, menarca, número de gestações e precocidade sexual) com alterações das células de Langerhans em mulheres com captura híbrida negativa para HPV.
Nelson Shozo Uchimura+4 more
doaj +1 more source
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj +1 more source
Shaping bursting by electrical coupling and noise [PDF]
Gap-junctional coupling is an important way of communication between neurons and other excitable cells. Strong electrical coupling synchronizes activity across cell ensembles. Surprisingly, in the presence of noise synchronous oscillations generated by an electrically coupled network may differ qualitatively from the oscillations produced by uncoupled ...
arxiv +1 more source
Learning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive response [PDF]
Cells of almost all solid tissues are connected with gap junctions which permit the direct transfer of ions and small molecules, integral to regulating coordinated function in the tissue. The pancreatic islets of Langerhans are responsible for secreting the hormone insulin in response to glucose stimulation.
arxiv +1 more source
From simplicity to complexity in current melanoma models
Abstract Despite the recent impressive clinical success of immunotherapy against melanoma, development of primary and adaptive resistance against immune checkpoint inhibitors remains a major issue in a large number of treated patients. This highlights the need for melanoma models that replicate the tumor's intricate dynamics in the tumor ...
Elisabetta Michielon+2 more
wiley +1 more source
The effects of beta-cell mass and function, intercellular coupling, and islet synchrony on $\textrm{Ca}^{2+}$ dynamics [PDF]
Type 2 diabetes (T2D) is a challenging metabolic disorder characterized by a substantial loss of $\beta$-cell mass and alteration of $\beta$-cell function in the islets of Langerhans, disrupting insulin secretion and glucose homeostasis. The mechanisms for deficiency in $\beta$-cell mass and function during the hyperglycemia development and T2D ...
arxiv +1 more source