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Langerhans Cell Histiocytosis [PDF]

open access: yesCancer Control, 2014
Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone disease to a life-threatening multisystem condition. LCH can occur at any age but is more frequent in the pediatric population. A neoplastic origin of this disease has been suggested
openaire   +3 more sources

Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages

open access: yesBMC Research Notes, 2011
Background Langerhans cells constitute a special subset of immature dendritic cells localized in the epidermis that play a key role in the skin's immune response.
da Silva Jorge P   +4 more
doaj   +1 more source

Langerhans cell histiocytosis

open access: yes, 2013
Definition: A histiocytary proliferation of granuloma-like aspect with unknown etiology that may involve bone marrow, internal organs, skin, and mucosae.
openaire   +4 more sources

Rho-associated kinase regulates Langerhans cell morphology and responsiveness to tissue damage

open access: yesCell Reports
Summary: Skin damage requires efficient immune cell responses to restore organ function. Epidermal-resident immune cells known as Langerhans cells use dendritic protrusions to surveil the skin microenvironment, which contains keratinocytes and peripheral
Eric Peterman   +3 more
doaj  

Assessment of antigen presenting cell infiltration in lung tissues of patients with bronchiectasis

open access: yesIndian Journal of Pathology and Microbiology, 2016
Background: Bronchiectasis is a chronic disease characterized by permanent dilatation of the conducting airways accompanied by sustained inflammation. Aims: To assess whether chronic inflammation of lungs in bronchiectasis is associated with alterations ...
Waseem M Hajjar   +5 more
doaj   +1 more source

Histiocitose de células de Langerhans: doença de Letterer-Siwe - importância do diagnóstico dermatológico em dois casos Langerhans cell histiocytosis: Letterer-Siwe disease - the importance of dermatological diagnosis in two cases

open access: yesAnais Brasileiros de Dermatologia, 2009
A histiocitose de células de Langerhans é proliferação clonal de células fenotipicamente semelhantes às células de Langerhans. Anteriormente denominada Letterer-Siwe, é a forma mais comum e mais grave dessa enfermidade, acometendo sobretudo crianças até ...
Leonardo Mello Ferreira   +4 more
doaj   +1 more source

Interactions of Human Dermal Dendritic Cells and Langerhans Cells Treated with Hyalomma Tick Saliva with Crimean-Congo Hemorrhagic Fever Virus

open access: yesViruses, 2018
Crimean-Congo hemorrhagic fever virus is one the most important and wide spread tick-borne viruses. Very little is known about the transmission from the tick and the early aspects of pathogenesis.
Sergio E. Rodriguez   +3 more
doaj   +1 more source

Langerhans Cell Histiocytosis in a Child with Unifocal Mandibular Lesion and Diabetes Insipidus: A Case Report

open access: yesمجله دانشکده پزشکی اصفهان, 2010
Background: Patients with Langerhans cell histiocytosis are at particularly high risk for central diabetes insipi-dus (CDI) due to hypothalamic-pituitary disease. Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by the
Zahra Alian   +2 more
doaj  

Vaginal Lactobacilli Induce Differentiation of Monocytic Precursors Toward Langerhans-like Cells: in Vitro Evidence

open access: yesFrontiers in Immunology, 2018
Lactobacilli have immunomodulatory mechanisms that affect the host cell immune system, leading to inhibition of HIV-1 transmission. Thus, lactobacilli as mucosal delivery vehicles for developing HIV-1 vaccines have attracted interest in recent years ...
Jie Song   +10 more
doaj   +1 more source

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