Results 111 to 120 of about 8,360 (233)

MicroRNAs regulate Dendritic Cell Development and Function [PDF]

, 2011
Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important.
Schnorfeil, Frauke Marie
core  

Systematic Chemoenzymatic Synthesis of O-Sulfated Sialyl Lewis x Antigens. [PDF]

, 2015
O-Sulfated sialyl Lewis x antigens play important roles in nature. However, due to their structural complexity, they are not readily accessible by either chemical or enzymatic synthetic processes.
Chen, Xi, Kenyond, Nicholas J, Li, Yanhong, Louie, Angelique Y, Muthana, Musleh M, Santra, Abhishek, Tasnima, Nova, Yu, Hai, Zeng, Jie   +8 more
core   +1 more source

Topographical variations in the skin barrier and their role in disease pathogenesis

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 7, Page 1228-1238, July 2025.
Unlike the gut, the skin appears uniform at first glance. However, histological and molecular biological research has revealed significant regional variations in the composition and function of its main barrier elements. In this review, we describe the topographical differences of four barrier elements in healthy skin: microbiome, chemical, physical ...
Z. Dajnoki, A. Kapitány, K. Eyerich, S. Eyerich, D. Törőcsik, A. Szegedi   +5 more
wiley   +1 more source

The Role of Langerin⁺ CD8α⁺ Dendritic Cells in Tumour Immunotherapy [PDF]

, 2021
<p>The immune system has the potential to selectively target and eliminate tumours cells. However, the induction of an immunosuppressive environment by factors released by tumours cells, or by the tumour stroma, in combination with difficulties in differentiating between healthy and malignant cells, contributes to inefficient or disabled anti ...
openaire   +1 more source

Langerhans cell histiocytosis in an adult patient

Vestnik Dermatologii i Venerologii, 2019
Aim: to present a clinical case of a rare dermatosis — Langerhans cell histiocytosis (LCH) in an adult patient.Materials and methods. A clinical and laboratory examination of a 64-year-old woman who had complained of rashes on the skin of the scalp, neck,
A. E. Karamova, V. V. Chikin, L. F. Znamenskaya, M. A. Nefedova, V. A. Mikhina, N. S. Battalova   +5 more
doaj   +1 more source

Lewis‐X‐Containing Triterpenoid Saponins Inhibit DC‐SIGN‐ and L‐SIGN‐Mediated Transfer of HIV‐1 Infection

Chemistry – A European Journal, Volume 31, Issue 32, June 6, 2025.
The convergent synthesis of Lewis‐X‐containing betulinic acid and echinocystic acid saponins (1 and 2) is presented. The synthetic saponins were shown to inhibit, at the low micromolar range, the DC‐SIGN‐ and L‐SIGN‐mediated transfer of HIV‐1 infection to CD4‐positive cells, whereas free Lewis‐X, aglycones, and structurally similar triterpenoid ...
Oscar Javier Gamboa Marin, Kurtis Ng, Nitish Verma, Assi Gérard Flavien Yapi, Ralph Pantophlet, Charles Gauthier   +5 more
wiley   +1 more source

Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells

EBioMedicine, 2018
Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity and ...
Daniela Y. Kitashima, Tetsuro Kobayashi, Therese Woodring, Kacey Idouchi, Thomas Doebel, Benjamin Voisin, Takeya Adachi, Takeshi Ouchi, Hayato Takahashi, Koji Nishifuji, Daniel H. Kaplan, Björn E. Clausen, Masayuki Amagai, Keisuke Nagao   +13 more
doaj   +1 more source

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]

, 2014
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Akula, Akula, Akula, Ambroziak, Armenian, Banchereau, Beltman, Birkmann, Blasig, Boshoff, Brayfield, Cai, Campadelli-Fiume, Carbone, Carbone, Castleman, Cesarman, Cesarman, Cesarman, Chan, Chang, Chehimi, Cheong, Cirone, Cirone, Clark, Coscoy, Cull, Cutler, de Witte, Della Bella, Dupin, Duus, Edelman, El-Daly, Enk, Farah, Frisch, Furio, Geissmann, Gessain, Gill, Granelli-Piperno, Gregory, Hahn, Hassman, Hensler, Hensler, Hislop, Hogg, Holmgren, Huang, Ishido, Iwasaki, Jacobson, Jenner, Jotwani, Kerur, King, Klechevsky, Knowlton, Knowlton, Koelle, Kwun, Lang, Li, Liao, Lin, Lisco, Liu, Mesri, Mesri, Mitterer, Montgomery, Moore, Munthe, Munz, Myoung, Nador, Nador, Neipel, Nickoloff, Oksenhendler, Orsini, Osman, Otsuki, Park, Pica, Qu, Rappocciolo, Rappocciolo, Rappocciolo, Ratzinger, Reed, Relloso, Rettig, Rezaee, Robey, Said, Sallusto, Samols, Santarelli, Sharma-Walia, Simonelli, Soilleux, Soilleux, Soulier, Stebbing, Ueno, Valladeau, Vieira, Walling, Wang, Wang, Wang, Wang, West, Wilkinson, Yan, Yi   +119 more
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Glycobiology of immune responses [PDF]

, 2012
Unlike their protein roommates and their nucleic acid cousins, carbohydrates remain an enigmatic arm of biology. The central reason for the difficulty in fully understanding how carbohydrate structure and biological function are tied is the non-template ...
Aarnoudse, Amith, Amith, Andersson, Angata, Anthony, Avril, Banh, Birkholz, Blasius, Blixt, Boscher, Bozzacco, Bozzacco, Brewer, Brockhausen, Brown, Burgdorf, Buzás, Caminischi, Carlin, Cedeno-Laurent, Comelli, Cooper, Crocker, Dai, Dam, Dardalhon, de Witte, Demetriou, Demotte, Denda-Nagai, Di Lella, Drickamer, Dube, Engering, Figdor, Forsman, Garcia-Vallejo, Garner, Geijtenbeek, Geijtenbeek, Geijtenbeek, Gow, Green, Grigorian, Gringhuis, Gringhuis, Harrison, Hiki, Idoyaga, Ilarregui, Jellusova, Jiang, Ju, Juszczynski, Kaneko, Kawasaki, Kel, Klechevsky, Krinos, Kuo, Lambert, Levine, Li, Liu, Liu, Lowe, Matsushita, Mitoma, Nicoll, Nothaft, Oberg, Ohta, Ohtsubo, Osorio, O’Reilly, O’Reilly, Padler-Karavani, Park, Pashov, Paul, Rabinovich, Rubinstein, Ryan, Saeland, Saeland, Salatino, Sancho, Sato, Singh, Singh, Singh, Soldati, Sperandio, Stanley, Stanley, Streng-Ouwehand, Sánchez-Navarro, Takahashi, Tang, Theodore, Toscano, Tsuboi, Unger, Van Die, Van Geet, van Gisbergen, van Gisbergen, van Kooyk, van Kooyk, van Vliet, van Vliet, Wang, Zelensky, Zhou, Zhu   +116 more
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Kutane Dendritische Zell-Subpopulationen in Pathogenese und Therapie dermatologischer Erkrankungen [PDF]

, 2018
Dendritische Zellen (DCs) sind die wichtigsten antigen-präsentierenden Zellen des Immunsystems. Sie stellen die Verbindung zwischen angeborenem und erworbenem Immunsystem dar und entscheiden über die Art der Immunantwort, über Toleranz oder Immunität ...
Terhorst-Molawi, Dorothea
core   +1 more source