Results 111 to 120 of about 8,574 (229)

The Clinicopathologic Spectrum of Rosai–Dorfman–Destombes Disease in Adults: An Analysis of 16 Cases

open access: yesEuropean Journal of Haematology, Volume 115, Issue 6, Page 555-564, December 2025.
ABSTRACT Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytic proliferation with protean clinical manifestations, resulting from the accumulation of activated histiocytes within nodal and extra‐nodal tissues. The diagnosis can be missed, particularly when biopsies are obtained from extra‐nodal sites, where histological features may be less ...
Mark Trinder   +8 more
wiley   +1 more source

Unraveling cutaneous histiocytosis: insights into histology, pathogenesis, diagnosis, and treatment pitfalls

open access: yesFrontiers in Medicine
Histiocytoses represent a group of diverse rare disorders characterized by the abnormal accumulation of cells derived from the mononuclear phagocyte system in various tissues and organs.
Lucian G. Scurtu   +5 more
doaj   +1 more source

Langerhans cell histiocytosis in an adult patient

open access: yesVestnik Dermatologii i Venerologii, 2019
Aim: to present a clinical case of a rare dermatosis — Langerhans cell histiocytosis (LCH) in an adult patient.Materials and methods. A clinical and laboratory examination of a 64-year-old woman who had complained of rashes on the skin of the scalp, neck,
A. E. Karamova   +5 more
doaj   +1 more source

MicroRNAs regulate Dendritic Cell Development and Function [PDF]

open access: yes, 2011
Dendritic cells (DCs) play a key role in the initiation of adaptive immune responses and the maintenance of self-tolerance. Due to their therapeutic potential, understanding the mechanisms that guide DC differentiation and effector functions is important.
Schnorfeil, Frauke Marie
core  

Targeted delivery of a vaccine protein to Langerhans cells in the human skin via the C‐type lectin receptor Langerin [PDF]

open access: hybrid, 2021
Lydia Bellmann   +19 more
openalex   +1 more source

Beyond Hepatitis: A Rare Case of Multisystem Langerhans Cell Histiocytosis in a Child

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare neoplastic disorder involving abnormal proliferation of dendritic cells, with clinical presentations ranging from isolated lesions to life‐threatening multisystem involvement. This case report describes a 26‐month‐old girl who presented with progressive jaundice, fever, hepatomegaly, pruritic scalp
Dilip Neupane   +4 more
wiley   +1 more source

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]

open access: yes, 2014
Human herpesvirus 8 (HHV-8; Kaposi's sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Akula   +119 more
core   +1 more source

Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells

open access: yesEBioMedicine, 2018
Langerhans cells (LCs) are antigen-presenting cells in the epidermis whose roles in antigen-specific immune regulation remain incompletely understood. Desmoglein 3 (Dsg3) is a keratinocyte cell-cell adhesion molecule critical for epidermal integrity and ...
Daniela Y. Kitashima   +13 more
doaj   +1 more source

Kutane Dendritische Zell-Subpopulationen in Pathogenese und Therapie dermatologischer Erkrankungen [PDF]

open access: yes, 2018
Dendritische Zellen (DCs) sind die wichtigsten antigen-präsentierenden Zellen des Immunsystems. Sie stellen die Verbindung zwischen angeborenem und erworbenem Immunsystem dar und entscheiden über die Art der Immunantwort, über Toleranz oder Immunität ...
Terhorst-Molawi, Dorothea
core   +1 more source

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